Between the 2000 and 2020 seasons, Albert Pujols launched the most homers, with 662 home runs.

Interpreted as:

most home runs by a player from 2000 to 2020

	NAME	HR	G	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Albert Pujols A. Pujols	662	2,862	10,839	1,843	3,236	669	16	2,100	1,331	108	1,304	114	41	12,394	5,923	1,347	1	115	312	399	.299	.377	.546	.924	2141	668.4	.387	142	656.7
2	Alex Rodriguez A. Rodriguez	548	2,142	7,994	1,528	2,324	388	20	1,623	1,128	152	1,792	211	44	9,364	4,396	956	0	90	93	208	.291	.385	.550	.935	1684	554.7	.397	143	508.3
3	David Ortiz D. Ortiz	531	2,297	8,293	1,361	2,379	609	19	1,716	1,273	33	1,647	16	9	9,689	4,619	1,159	2	88	206	225	.287	.380	.557	.937	1706	556	.394	141	483.8
4	Miguel Cabrera M. Cabrera	487	2,457	9,153	1,457	2,866	581	17	1,729	1,159	64	1,812	39	21	10,467	4,942	1,085	5	86	235	321	.313	.391	.540	.931	1845	607.3	.393	145	568.5
5	Adam Dunn A. Dunn	462	2,001	6,883	1,097	1,631	334	10	1,168	1,317	86	2,379	63	25	8,328	3,371	806	2	40	122	100	.237	.364	.490	.854	1285	297.9	.367	123	240
6	Adrian Beltre A. Beltre	455	2,704	10,335	1,422	2,976	600	33	1,618	773	88	1,590	100	34	11,302	5,007	1,088	8	98	100	271	.288	.340	.484	.824	1608	265.5	.352	117	222.6
7	Edwin Encarnacion E. Encarnacion	424	1,960	7,040	1,099	1,832	370	10	1,261	903	105	1,426	61	14	8,114	3,494	804	0	66	54	185	.260	.350	.496	.846	1233	280.2	.362	125	235.4
8	Nelson Cruz N. Cruz	417	1,742	6,397	952	1,777	330	13	1,152	632	73	1,625	76	32	7,151	3,384	760	2	47	66	147	.278	.347	.529	.876	1143	309.1	.371	133	281.2
9	Jim Thome J. Thome	416	1,627	5,345	974	1,445	270	10	1,120	1,101	40	1,666	3	9	6,531	2,983	696	0	45	123	101	.270	.396	.558	.954	1201	402.9	.402	145	365.9
10	Carlos Beltran C. Beltran	413	2,416	9,047	1,458	2,515	533	68	1,472	1,035	46	1,660	282	41	10,245	4,423	1,014	18	99	102	184	.278	.352	.489	.841	1518	296.4	.359	120	251.8
11	Alfonso Soriano A. Soriano	411	1,966	7,742	1,150	2,094	481	31	1,158	496	86	1,800	289	83	8,387	3,870	923	9	54	68	123	.270	.319	.500	.819	1163	162.4	.348	111	113.3
12	Mark Teixeira M. Teixeira	409	1,862	6,936	1,099	1,862	408	18	1,298	918	111	1,441	26	7	8,029	3,533	835	0	64	91	158	.268	.360	.509	.869	1268	317.6	.371	127	262.4
13	Paul Konerko P. Konerko	408	2,126	7,656	1,070	2,141	375	4	1,302	859	99	1,281	8	3	8,694	3,748	787	0	80	80	252	.280	.356	.490	.846	1314	271.1	.363	120	213.3
14	Ryan Howard R. Howard	382	1,572	5,707	848	1,475	277	21	1,194	709	59	1,843	12	5	6,530	2,940	680	0	55	154	116	.258	.343	.515	.859	976	212.1	.361	121	175.3
15	Aramis Ramirez A. Ramirez	380	2,104	7,829	1,073	2,234	484	22	1,386	609	123	1,157	29	17	8,647	3,902	886	1	85	58	230	.285	.343	.498	.841	1283	254.5	.360	117	186.8
16	Lance Berkman L. Berkman	362	1,845	6,398	1,136	1,883	420	30	1,219	1,189	66	1,279	81	47	7,707	3,449	812	1	53	160	145	.294	.407	.539	.946	1412	479.8	.402	144	434.4
17	Vladimir Guerrero V. Guerrero	357	1,729	6,570	1,072	2,092	381	32	1,215	621	82	786	153	74	7,327	3,608	770	0	54	221	232	.318	.381	.549	.931	1271	379.2	.389	136	340.4
18	Manny Ramirez M. Ramirez	357	1,453	5,213	971	1,642	344	11	1,149	874	75	1,150	11	10	6,211	3,079	712	0	49	178	154	.315	.417	.591	1.008	1241	479.2	.421	157	445.5
19	Andruw Jones A. Jones	354	1,691	5,920	947	1,497	290	21	1,032	712	80	1,380	78	32	6,774	2,891	665	0	62	48	158	.253	.338	.488	.826	970	140.2	.353	112	105.8
20	Ryan Braun R. Braun	352	1,766	6,622	1,080	1,963	408	49	1,154	586	77	1,363	216	60	7,329	3,525	809	0	44	56	179	.296	.358	.532	.891	1210	352.7	.379	135	310.8
21	Jose Bautista J. Bautista	344	1,798	6,051	1,022	1,496	312	17	975	1,032	80	1,394	70	32	7,244	2,874	673	23	58	58	170	.247	.361	.475	.836	1085	241.2	.362	126	211.3
22	Curtis Granderson C. Granderson	344	2,057	7,236	1,217	1,800	346	95	937	924	67	1,916	153	50	8,306	3,368	785	30	49	31	64	.249	.337	.465	.803	1149	173.1	.347	115	147.8
23	Torii Hunter T. Hunter	344	2,230	8,456	1,244	2,350	480	37	1,354	633	91	1,663	185	92	9,251	3,936	861	5	66	51	252	.278	.332	.465	.798	1248	151.3	.344	112	129.1
24	Carlos Lee C. Lee	342	1,972	7,491	1,059	2,129	437	17	1,279	642	43	912	121	45	8,269	3,626	796	2	91	60	195	.284	.340	.484	.824	1178	177.1	.352	113	139.4
25	Robinson Cano R. Cano	334	2,234	8,673	1,257	2,624	571	33	1,302	616	85	1,189	51	38	9,446	4,263	938	10	62	112	284	.303	.352	.492	.844	1411	303.4	.360	125	284.7