most pitching strikeouts vs cubs all-time

Steve Carlton has fanned the most career hitters versus the Cubs, with 421 strikeouts.

Interpreted as:

most pitching strikeouts by a player vs cubs all-time

	NAME	SO	G	W	L	W%	GS	ERA	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	H/9
1	Steve Carlton S. Carlton	421	77	41	20	.672	72	3.11	29	7	0	533.0	487	184	212	49	156	10	2	16	2,207	16	7.11	2.63	2.70	0.83	19.1	7.1	1.21	.279	3.58	8.22
2	Dazzy Vance D. Vance	383	71	34	21	.618	55	3.28	32	4	2	467.0	430	170	192	27	130	7	9		1,924	4	7.38	2.51	2.95	0.52	19.9	6.8	1.20	.293	3.70	8.29
3	Don Drysdale D. Drysdale	376	69	30	19	.612	60	2.67	27	7	2	465.2	400	138	161	35	115	23	7	17	1,892	15	7.27	2.22	3.27	0.68	19.9	6.1	1.11	.272	3.11	7.73
4	Sandy Koufax S. Koufax	368	51	21	12	.636	40	2.44	17	3	1	313.2	197	85	97	27	133	2	5	9	1,262	14	10.56	3.82	2.77	0.77	29.2	10.5	1.05	.232	2.78	5.65
5	Christy Mathewson C. Mathewson	355	96	46	39	.541	87	0.89	75	14	5	749.1	654		283	18	113	4	8			17	4.26	1.36	3.14	0.22		3.8	1.02	.257	3.40	7.85
6	Warren Spahn W. Spahn	342	87	48	19	.716	74	2.85	44	10	4	580.1	529	184	207	50	123	3	10	2	2,344	7	5.30	1.91	2.78	0.78	14.6	5.2	1.12	.262	3.21	8.20
7	Bob Gibson B. Gibson	338	58	28	22	.560	53	2.95	33	11	1	440.0	367	144	154	27	161	6	2	24	1,823	13	6.91	3.29	2.10	0.55	18.5	8.8	1.20	.263	3.15	7.51
8	Tom Seaver T. Seaver	299	53	24	18	.571	52	2.51	17	4	0	387.2	311	108	117	33	126	7	1	12	1,569	8	6.94	2.93	2.37	0.77	19.1	8.0	1.13	.252	2.72	7.22
9	Robin Roberts R. Roberts	284	73	36	24	.600	64	2.98	39	8	3	521.2	475	173	188	50	90	13	7		2,096	2	4.90	1.55	3.16	0.86	13.5	4.3	1.08	.256	3.24	8.19
10	Carl Hubbell C. Hubbell	274	84	33	27	.550	68	3.20	33	4	3	542.2	550	193	224	42	117	11	12		2,262	9	4.54	1.94	2.34	0.70	12.1	5.2	1.23	.279	3.71	9.12
11	Paul Derringer P. Derringer	268	81	38	24	.613	65	2.63	41	5	1	561.1	515	164	197	28	110	4	10		2,288	10	4.30	1.76	2.44	0.45	11.7	4.8	1.11	.259	3.16	8.26
12	Curt Simmons C. Simmons	261	68	25	19	.568	59	3.46	20	5	1	429.0	420	165	195	41	143	7	5		1,825	11	5.48	3.00	1.83	0.86	14.3	7.8	1.31	.276	4.09	8.81
13	Adam Wainwright A. Wainwright	254	59	19	16	.543	50	4.05	0	0	0	311.1	320	140	144	28	93	9	1	7	1,322	5	7.34	2.69	2.73	0.81	19.2	7.0	1.33	.311	4.16	9.25
14	Bob Friend B. Friend	247	72	27	22	.551	59	3.52	22	5	2	449.2	442	176	194	30	101	5	6	19	1,861	8	4.94	2.02	2.45	0.60	13.3	5.4	1.21	.279	3.88	8.85
15	Phil Niekro P. Niekro	241	62	27	17	.614	52	3.19	24	5	2	395.1	375	140	168	38	97	17	7	11	1,641	14	5.49	2.21	2.48	0.87	14.7	5.9	1.19	.270	3.82	8.54
16	Dwight Gooden D. Gooden	235	40	28	4	.875	39	3.32	11	3	1	284.1	264	105	116	18	90	7	1	3	1,190	5	7.44	2.85	2.61	0.57	19.7	7.6	1.25	.293	3.67	8.36
17	Grover Alexander G. Alexander	234	64	30	23	.566	58	2.62	38	10	1	457.1	395		172	26	105	7	3			3	4.60	2.07	2.23	0.51		5.7	1.09	.251	3.38	7.77
18	Harvey Haddix H. Haddix	232	45	20	12	.625	37	3.08	16	5	1	286.2	262	98	109	30	70	3	4		1,172	12	7.28	2.20	3.31	0.94	19.8	6.0	1.16	.277	3.42	8.23
19	Rube Marquard R. Marquard	229	74	25	27	.481	61	2.66	24	4	2	453.2	458		214	14	138	6	9		1,915	14	4.54	2.74	1.66	0.28	12.0	7.2	1.31	.291	4.25	9.09
20	Joe Nuxhall J. Nuxhall	220	70	19	16	.543	36	3.30	11	2	4	316.1	291	116	130	27	103	10	17	5	1,322	7	6.26	2.93	2.14	0.77	16.6	7.8	1.25	.274	3.70	8.28
21	Van Mungo V. Mungo	217	59	19	19	.500	39	3.42	21	2	4	355.2	328	135	157	18	152	8	11		1,503	8	5.49	3.85	1.43	0.46	14.4	10.1	1.35	.280	3.97	8.30
22	Burleigh Grimes B. Grimes	217	83	43	26	.623	68	3.30	46	7	3	600.0	637		272	18	210	14	12		2,585	9	3.26	3.15	1.03	0.27	8.4	8.1	1.41	.291	4.08	9.56
23	Wilbur Cooper W. Cooper	217	79	30	27	.526	58	2.60	38	7	4	509.2	489	147	194	8	123	11	17		2,091	6	3.83	2.17	1.76	0.14	10.4	5.9	1.20	.278	3.43	8.64
24	Don Sutton D. Sutton	215	49	18	20	.474	44	3.52	11	0	1	301.1	272	118	135	23	81	3	2	6	1,246	8	6.42	2.42	2.65	0.69	17.3	6.5	1.17	.269	4.03	8.12
25	Juan Marichal J. Marichal	213	36	23	8	.742	36	2.60	20	4	0	283.1	248	82	98	24	66	2	0	7	1,157	0	6.77	2.10	3.23	0.76	18.4	5.7	1.11	.263	3.11	7.88