17 players are tied for the most strikeouts + home runs in a game, with 6. The first three are Mike Tauchman on June 23, 2021, Dexter Fowler on September 24, 2019 and Austin Hays on September 23, 2019.

Interpreted as:

most strikeouts+home runs by a player in a regular-season game

	NAME	SO+HR	SO	HR	DATE	TM		OPP	AB	R	H	2B	3B	RBI	BB	HBP	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP
1	Mike Tauchman M. Tauchman	6	5	1	6/23/2021	SFG	@	LAA	6	1	1	0	0	3	0	0	0	0	6	4	1	0	0	0	0
2	Dexter Fowler D. Fowler	6	5	1	9/24/2019	STL	@	ARI	8	1	1	0	0	1	1	0	0	0	9	4	1	0	0	0	0
3	Austin Hays A. Hays	6	4	2	9/23/2019	BAL	@	TOR	8	2	3	0	0	5	0	0	1	0	8	9	2	0	0	0	0
4	Yasmani Grandal Y. Grandal	6	4	2	7/24/2018	LAD	@	PHI	7	2	3	0	0	2	0	0	0	0	7	9	2	0	0	0	0
5	Brian Dozier B. Dozier	6	5	1	7/30/2017	MIN	@	OAK	6	1	1	0	0	1	0	0	0	0	6	4	1	0	0	0	0
6	Brandon Moss B. Moss	6	4	2	4/29/2013	OAK	vs	LAA	8	3	3	0	0	3	1	0	1	0	9	9	2	0	0	0	0
7	Evan Longoria E. Longoria	6	4	2	8/4/2009	TBR	vs	BOS	6	2	2	0	0	3	1	0	0	0	7	8	2	0	0	1	0
8	Geoff Jenkins G. Jenkins	6	6	0	6/8/2004	MIL	@	ANA	7	0	0	0	0	0	0	0	0	0	7	0	0	0	0	0	0
9	Sammy Sosa S. Sosa	6	5	1	6/9/2000	CHC	@	CWS	6	1	1	0	0	2	0	0	0	0	6	4	1	0	0	0	0
10	Alex Gonzalez A. Gonzalez	6	6	0	9/9/1998	TOR	vs	CLE	6	0	0	0	0	0	0	0	0	0	6	0	0	0	0	0	0
11	Ray Lankford R. Lankford	6	5	1	8/8/1998	STL	vs	CHC	7	1	2	0	0	3	0	0	0	0	7	5	1	0	0	0	0
12	Sam Horn S. Horn	6	6	0	7/17/1991	BAL	@	KCR	7	2	1	1	0	0	1	0	0	0	8	2	1	0	0	0	0
13	Cecil Cooper C. Cooper	6	6	0	6/14/1974	BOS	@	CAL	8	0	0	0	0	0	0	0	0	0	8	0	0	0	0	0	0
14	Billy Cowan B. Cowan	6	6	0	7/9/1971	CAL	@	OAK	8	0	0	0	0	0	0	0	0	0	8	0	0	0	0	0	0
15	Rick Reichardt R. Reichardt	6	6	0	5/31/1966	CAL	vs	CLE	8	0	0	0	0	0	0	0	0	0	8	0	0	0	0	0	0
16	Don Hoak D. Hoak	6	6	0	5/2/1956	CHC	vs	NYG	7	0	1	0	0	0	1	0	0	0	9	1	0	1	0	0	0
17	Carl Weilman C. Weilman	6	6	0	7/25/1913	SLA	@	WSH	6	0	0	0	0		0	0	0		6	0	0	0
18	Liover Peguero L. Peguero	5	2	3	8/2/2025	PIT	@	COL	5	3	3	0	0	5	0	0	0	0	5	12	3	0	0	0	0
19	Cal Raleigh C. Raleigh	5	5	0	8/2/2025	SEA	vs	TEX	5	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
20	Matt Chapman M. Chapman	5	3	2	7/27/2025	SFG	vs	NYM	5	2	2	0	0	3	0	0	0	0	5	8	2	0	0	0	0
21	Corbin Carroll C. Carroll	5	4	1	7/9/2025	AZ	@	SDP	5	1	1	0	0	1	0	0	0	0	5	4	1	0	0	0	0
22	Ryan McMahon R. McMahon	5	4	1	6/20/2025	COL	vs	AZ	5	1	1	0	0	1	0	0	0	0	5	4	1	0	0	0	0
23	Austin Slater A. Slater	5	5	0	6/12/2025	CWS	@	HOU	5	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
24	Trevor Story T. Story	5	4	1	5/10/2025	BOS	@	KCR	5	1	1	0	0	3	0	0	0	0	5	4	1	0	0	0	0
25	Tyler Stephenson T. Stephenson	5	5	0	5/6/2025	CIN	@	ATL	5	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0