Between April 13, 1999 and June 6, 2025, Justin Verlander fanned the most hitters, with 3,457 strikeouts.
- Regular season
| NAME | SO | G | W | L | W% | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | H/9 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | J. Verlander | 3,457 | 536 | 262 | 150 | .636 | 536 | 3.31 | 26 | 9 | 0 | 3467.2 | 2,943 | 1,277 | 1,381 | 363 | 973 | 116 | 0 | 27 | 14,170 | 97 | 8.97 | 2.53 | 3.55 | 0.94 | 24.4 | 6.9 | 1.13 | .279 | 3.58 | 7.64 |
| 2 |  | M. Scherzer | 3,408 | 467 | 215 | 112 | .657 | 458 | 3.16 | 12 | 5 | 0 | 2881.0 | 2,349 | 1,012 | 1,085 | 337 | 756 | 112 | 2 | 20 | 11,640 | 78 | 10.65 | 2.36 | 4.51 | 1.05 | 29.3 | 6.5 | 1.08 | .286 | 3.39 | 7.34 |
| 3 |  | CC Sabathia | 3,093 | 561 | 251 | 161 | .609 | 560 | 3.74 | 38 | 12 | 0 | 3577.1 | 3,404 | 1,485 | 1,623 | 382 | 1,099 | 123 | 0 | 44 | 14,989 | 74 | 7.78 | 2.76 | 2.81 | 0.96 | 20.6 | 7.3 | 1.26 | .294 | 4.08 | 8.56 |
| 4 |  | Z. Greinke | 2,979 | 586 | 225 | 156 | .591 | 541 | 3.49 | 17 | 5 | 1 | 3389.1 | 3,207 | 1,315 | 1,410 | 367 | 762 | 79 | 8 | 25 | 13,877 | 101 | 7.91 | 2.02 | 3.91 | 0.97 | 21.5 | 5.5 | 1.17 | .293 | 3.74 | 8.52 |
| 5 |  | C. Kershaw | 2,976 | 436 | 212 | 94 | .693 | 433 | 2.52 | 25 | 15 | 0 | 2758.1 | 2,108 | 771 | 846 | 229 | 687 | 44 | 1 | 28 | 10,886 | 104 | 9.71 | 2.24 | 4.33 | 0.75 | 27.3 | 6.3 | 1.01 | .270 | 2.76 | 6.88 |
| 6 |  | C. Hamels | 2,560 | 423 | 163 | 122 | .572 | 422 | 3.43 | 17 | 7 | 0 | 2698.0 | 2,424 | 1,027 | 1,103 | 310 | 767 | 100 | 0 | 43 | 11,115 | 57 | 8.54 | 2.56 | 3.34 | 1.03 | 23.0 | 6.9 | 1.18 | .287 | 3.68 | 8.09 |
| 7 |  | F. Hernandez | 2,524 | 419 | 169 | 136 | .554 | 418 | 3.42 | 25 | 11 | 0 | 2729.2 | 2,487 | 1,037 | 1,157 | 264 | 805 | 105 | 0 | 16 | 11,284 | 156 | 8.32 | 2.65 | 3.14 | 0.87 | 22.4 | 7.1 | 1.21 | .293 | 3.81 | 8.20 |
| 8 |  | R. Johnson | 2,522 | 320 | 159 | 87 | .646 | 314 | 3.23 | 43 | 14 | 0 | 2141.0 | 1,812 | 769 | 871 | 239 | 546 | 97 | 3 | 25 | 8,702 | 38 | 10.60 | 2.30 | 4.62 | 1.00 | 29.0 | 6.3 | 1.10 | .297 | 3.66 | 7.62 |
| 9 | | A.J. Burnett | 2,513 | 435 | 164 | 157 | .511 | 430 | 3.99 | 24 | 10 | 0 | 2731.1 | 2,519 | 1,210 | 1,328 | 263 | 1,100 | 143 | 1 | 35 | 11,665 | 161 | 8.28 | 3.62 | 2.28 | 0.87 | 21.5 | 9.4 | 1.32 | .295 | 4.38 | 8.30 |
| 10 |  | C. Sale | 2,510 | 385 | 141 | 87 | .618 | 305 | 3.03 | 16 | 3 | 12 | 2032.0 | 1,658 | 685 | 738 | 209 | 478 | 126 | 25 | 15 | 8,190 | 47 | 11.12 | 2.12 | 5.25 | 0.93 | 30.6 | 5.8 | 1.05 | .298 | 3.27 | 7.34 |
| 11 |  | J. Lester | 2,488 | 452 | 200 | 117 | .631 | 451 | 3.66 | 15 | 4 | 0 | 2740.0 | 2,610 | 1,114 | 1,215 | 294 | 892 | 90 | 0 | 13 | 11,487 | 63 | 8.17 | 2.93 | 2.79 | 0.97 | 21.7 | 7.8 | 1.28 | .300 | 3.99 | 8.57 |
| 12 | | J. Vazquez | 2,392 | 416 | 160 | 145 | .525 | 410 | 4.10 | 28 | 8 | 0 | 2662.2 | 2,582 | 1,213 | 1,307 | 342 | 694 | 77 | 4 | 56 | 11,148 | 73 | 8.09 | 2.35 | 3.45 | 1.16 | 21.5 | 6.2 | 1.23 | .293 | 4.42 | 8.73 |
| 13 |  | B. Colon | 2,309 | 514 | 228 | 172 | .570 | 503 | 4.10 | 31 | 11 | 0 | 3158.2 | 3,279 | 1,440 | 1,561 | 411 | 823 | 58 | 2 | 41 | 13,327 | 36 | 6.58 | 2.34 | 2.81 | 1.17 | 17.3 | 6.2 | 1.30 | .295 | 4.45 | 9.34 |
| 14 | | J. Lackey | 2,294 | 448 | 188 | 147 | .561 | 446 | 3.92 | 18 | 8 | 0 | 2840.1 | 2,862 | 1,237 | 1,347 | 319 | 815 | 133 | 0 | 32 | 12,030 | 125 | 7.27 | 2.58 | 2.81 | 1.01 | 19.1 | 6.8 | 1.29 | .300 | 4.27 | 9.07 |
| 15 |  | G. Cole | 2,251 | 317 | 153 | 80 | .657 | 317 | 3.18 | 8 | 5 | 0 | 1954.0 | 1,627 | 690 | 740 | 217 | 500 | 61 | 0 | 7 | 7,861 | 58 | 10.37 | 2.30 | 4.50 | 1.00 | 28.6 | 6.4 | 1.09 | .292 | 3.41 | 7.49 |
| 16 | | J. Shields | 2,234 | 407 | 145 | 139 | .511 | 405 | 4.01 | 23 | 9 | 0 | 2616.0 | 2,581 | 1,167 | 1,267 | 361 | 746 | 97 | 1 | 22 | 10,993 | 107 | 7.69 | 2.57 | 2.99 | 1.24 | 20.3 | 6.8 | 1.27 | .294 | 4.36 | 8.88 |
| 17 | | J. Peavy | 2,207 | 388 | 152 | 126 | .547 | 377 | 3.63 | 15 | 6 | 0 | 2377.0 | 2,134 | 960 | 1,011 | 259 | 708 | 78 | 3 | 42 | 9,838 | 46 | 8.36 | 2.68 | 3.12 | 0.98 | 22.4 | 7.2 | 1.20 | .285 | 3.83 | 8.08 |
| 18 | | A. Wainwright | 2,202 | 478 | 200 | 128 | .610 | 411 | 3.53 | 28 | 11 | 3 | 2668.1 | 2,577 | 1,047 | 1,117 | 233 | 736 | 81 | 13 | 40 | 11,116 | 51 | 7.43 | 2.48 | 2.99 | 0.79 | 19.8 | 6.6 | 1.24 | .298 | 3.77 | 8.69 |
| 19 | | R. Halladay | 2,101 | 412 | 201 | 105 | .657 | 388 | 3.40 | 66 | 20 | 0 | 2730.2 | 2,636 | 1,031 | 1,131 | 234 | 586 | 81 | 5 | 28 | 11,215 | 56 | 6.92 | 1.93 | 3.59 | 0.77 | 18.7 | 5.2 | 1.18 | .292 | 3.73 | 8.69 |
| 20 |  | C. Morton | 2,099 | 397 | 140 | 130 | .519 | 390 | 4.07 | 3 | 2 | 0 | 2179.1 | 2,049 | 985 | 1,084 | 213 | 814 | 189 | 1 | 25 | 9,348 | 70 | 8.67 | 3.36 | 2.58 | 0.88 | 22.5 | 8.7 | 1.31 | .304 | 4.48 | 8.46 |
| 21 | | T. Hudson | 2,080 | 482 | 222 | 133 | .625 | 479 | 3.49 | 26 | 13 | 0 | 3126.2 | 2,957 | 1,213 | 1,319 | 248 | 917 | 124 | 0 | 84 | 13,005 | 84 | 5.99 | 2.64 | 2.27 | 0.71 | 16.0 | 7.1 | 1.24 | .281 | 3.80 | 8.51 |
| 22 |  | D. Price | 2,076 | 400 | 157 | 82 | .657 | 322 | 3.32 | 17 | 3 | 3 | 2143.2 | 1,930 | 790 | 865 | 221 | 562 | 63 | 19 | 16 | 8,807 | 40 | 8.72 | 2.36 | 3.69 | 0.93 | 23.6 | 6.4 | 1.16 | .290 | 3.63 | 8.10 |
| 23 |  | M. Bumgarner | 2,070 | 358 | 134 | 124 | .519 | 355 | 3.47 | 16 | 7 | 0 | 2209.1 | 2,007 | 853 | 933 | 258 | 544 | 89 | 1 | 38 | 9,098 | 29 | 8.43 | 2.22 | 3.81 | 1.05 | 22.8 | 6.0 | 1.15 | .285 | 3.80 | 8.18 |
| 24 | | R. Dempster | 2,040 | 565 | 131 | 128 | .506 | 340 | 4.29 | 11 | 3 | 87 | 2332.1 | 2,275 | 1,111 | 1,203 | 261 | 1,033 | 82 | 185 | 46 | 10,140 | 75 | 7.87 | 3.99 | 1.97 | 1.01 | 20.1 | 10.2 | 1.42 | .300 | 4.64 | 8.78 |
| 25 | | L. Lynn | 2,015 | 364 | 143 | 99 | .591 | 340 | 3.74 | 4 | 2 | 1 | 2006.1 | 1,856 | 834 | 916 | 231 | 704 | 89 | 4 | 21 | 8,520 | 61 | 9.04 | 3.16 | 2.86 | 1.04 | 23.7 | 8.3 | 1.28 | .296 | 4.11 | 8.33 |
StatMuse has game-level data for strikeouts going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
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