Between August 4, 1999 and June 19, 2025, Justin Verlander struck out the most batters, with 3,463 strikeouts.
- Regular season
| NAME | SO | G | W | L | W% | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | H/9 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | J. Verlander | 3,463 | 537 | 262 | 151 | .634 | 537 | 3.32 | 26 | 9 | 0 | 3472.1 | 2,950 | 1,280 | 1,385 | 364 | 974 | 116 | 0 | 27 | 14,192 | 97 | 8.98 | 2.52 | 3.56 | 0.94 | 24.4 | 6.9 | 1.13 | .279 | 3.59 | 7.65 |
| 2 |  | M. Scherzer | 3,408 | 467 | 215 | 112 | .657 | 458 | 3.16 | 12 | 5 | 0 | 2881.0 | 2,349 | 1,012 | 1,085 | 337 | 756 | 112 | 2 | 20 | 11,640 | 78 | 10.65 | 2.36 | 4.51 | 1.05 | 29.3 | 6.5 | 1.08 | .286 | 3.39 | 7.34 |
| 3 |  | CC Sabathia | 3,093 | 561 | 251 | 161 | .609 | 560 | 3.74 | 38 | 12 | 0 | 3577.1 | 3,404 | 1,485 | 1,623 | 382 | 1,099 | 123 | 0 | 44 | 14,989 | 74 | 7.78 | 2.76 | 2.81 | 0.96 | 20.6 | 7.3 | 1.26 | .294 | 4.08 | 8.56 |
| 4 |  | C. Kershaw | 2,988 | 438 | 214 | 94 | .695 | 435 | 2.51 | 25 | 15 | 0 | 2770.1 | 2,117 | 772 | 847 | 229 | 688 | 44 | 1 | 28 | 10,931 | 104 | 9.71 | 2.24 | 4.34 | 0.74 | 27.3 | 6.3 | 1.01 | .270 | 2.75 | 6.88 |
| 5 |  | Z. Greinke | 2,979 | 586 | 225 | 156 | .591 | 541 | 3.49 | 17 | 5 | 1 | 3389.1 | 3,207 | 1,315 | 1,410 | 367 | 762 | 79 | 8 | 25 | 13,877 | 101 | 7.91 | 2.02 | 3.91 | 0.97 | 21.5 | 5.5 | 1.17 | .293 | 3.74 | 8.52 |
| 6 |  | C. Hamels | 2,560 | 423 | 163 | 122 | .572 | 422 | 3.43 | 17 | 7 | 0 | 2698.0 | 2,424 | 1,027 | 1,103 | 310 | 767 | 100 | 0 | 43 | 11,115 | 57 | 8.54 | 2.56 | 3.34 | 1.03 | 23.0 | 6.9 | 1.18 | .287 | 3.68 | 8.09 |
| 7 |  | C. Sale | 2,528 | 387 | 143 | 87 | .622 | 307 | 3.02 | 16 | 3 | 12 | 2047.2 | 1,668 | 686 | 739 | 209 | 481 | 126 | 25 | 15 | 8,249 | 47 | 11.11 | 2.11 | 5.26 | 0.92 | 30.6 | 5.8 | 1.05 | .297 | 3.25 | 7.33 |
| 8 |  | F. Hernandez | 2,524 | 419 | 169 | 136 | .554 | 418 | 3.42 | 25 | 11 | 0 | 2729.2 | 2,487 | 1,037 | 1,157 | 264 | 805 | 105 | 0 | 16 | 11,284 | 156 | 8.32 | 2.65 | 3.14 | 0.87 | 22.4 | 7.1 | 1.21 | .293 | 3.81 | 8.20 |
| 9 | | A.J. Burnett | 2,513 | 435 | 164 | 157 | .511 | 430 | 3.99 | 24 | 10 | 0 | 2731.1 | 2,519 | 1,210 | 1,328 | 263 | 1,100 | 143 | 1 | 35 | 11,665 | 161 | 8.28 | 3.62 | 2.28 | 0.87 | 21.5 | 9.4 | 1.32 | .295 | 4.38 | 8.30 |
| 10 |  | J. Lester | 2,488 | 452 | 200 | 117 | .631 | 451 | 3.66 | 15 | 4 | 0 | 2740.0 | 2,610 | 1,114 | 1,215 | 294 | 892 | 90 | 0 | 13 | 11,487 | 63 | 8.17 | 2.93 | 2.79 | 0.97 | 21.7 | 7.8 | 1.28 | .300 | 3.99 | 8.57 |
| 11 | | J. Vazquez | 2,333 | 402 | 155 | 140 | .525 | 396 | 4.05 | 26 | 8 | 0 | 2580.2 | 2,502 | 1,162 | 1,251 | 329 | 668 | 73 | 4 | 54 | 10,798 | 72 | 8.14 | 2.33 | 3.49 | 1.15 | 21.6 | 6.2 | 1.23 | .294 | 4.36 | 8.73 |
| 12 | | J. Lackey | 2,294 | 448 | 188 | 147 | .561 | 446 | 3.92 | 18 | 8 | 0 | 2840.1 | 2,862 | 1,237 | 1,347 | 319 | 815 | 133 | 0 | 32 | 12,030 | 125 | 7.27 | 2.58 | 2.81 | 1.01 | 19.1 | 6.8 | 1.29 | .300 | 4.27 | 9.07 |
| 13 |  | R. Johnson | 2,294 | 298 | 149 | 79 | .654 | 292 | 3.29 | 35 | 12 | 0 | 1971.1 | 1,679 | 720 | 816 | 223 | 506 | 91 | 3 | 23 | 8,029 | 35 | 10.47 | 2.31 | 4.53 | 1.02 | 28.6 | 6.3 | 1.11 | .296 | 3.73 | 7.67 |
| 14 |  | G. Cole | 2,251 | 317 | 153 | 80 | .657 | 317 | 3.18 | 8 | 5 | 0 | 1954.0 | 1,627 | 690 | 740 | 217 | 500 | 61 | 0 | 7 | 7,861 | 58 | 10.37 | 2.30 | 4.50 | 1.00 | 28.6 | 6.4 | 1.09 | .292 | 3.41 | 7.49 |
| 15 | | J. Shields | 2,234 | 407 | 145 | 139 | .511 | 405 | 4.01 | 23 | 9 | 0 | 2616.0 | 2,581 | 1,167 | 1,267 | 361 | 746 | 97 | 1 | 22 | 10,993 | 107 | 7.69 | 2.57 | 2.99 | 1.24 | 20.3 | 6.8 | 1.27 | .294 | 4.36 | 8.88 |
| 16 | | J. Peavy | 2,207 | 388 | 152 | 126 | .547 | 377 | 3.63 | 15 | 6 | 0 | 2377.0 | 2,134 | 960 | 1,011 | 259 | 708 | 78 | 3 | 42 | 9,838 | 46 | 8.36 | 2.68 | 3.12 | 0.98 | 22.4 | 7.2 | 1.20 | .285 | 3.83 | 8.08 |
| 17 |  | B. Colon | 2,203 | 494 | 219 | 169 | .564 | 483 | 4.09 | 31 | 11 | 0 | 3031.2 | 3,156 | 1,377 | 1,494 | 393 | 776 | 52 | 2 | 36 | 12,785 | 33 | 6.54 | 2.30 | 2.84 | 1.17 | 17.2 | 6.1 | 1.30 | .295 | 4.44 | 9.37 |
| 18 | | A. Wainwright | 2,202 | 478 | 200 | 128 | .610 | 411 | 3.53 | 28 | 11 | 3 | 2668.1 | 2,577 | 1,047 | 1,117 | 233 | 736 | 81 | 13 | 40 | 11,116 | 51 | 7.43 | 2.48 | 2.99 | 0.79 | 19.8 | 6.6 | 1.24 | .298 | 3.77 | 8.69 |
| 19 |  | C. Morton | 2,121 | 400 | 142 | 130 | .522 | 393 | 4.06 | 3 | 2 | 0 | 2192.2 | 2,066 | 990 | 1,089 | 213 | 819 | 191 | 1 | 25 | 9,409 | 70 | 8.71 | 3.36 | 2.59 | 0.87 | 22.5 | 8.7 | 1.32 | .306 | 4.47 | 8.48 |
| 20 |  | D. Price | 2,076 | 400 | 157 | 82 | .657 | 322 | 3.32 | 17 | 3 | 3 | 2143.2 | 1,930 | 790 | 865 | 221 | 562 | 63 | 19 | 16 | 8,807 | 40 | 8.72 | 2.36 | 3.69 | 0.93 | 23.6 | 6.4 | 1.16 | .290 | 3.63 | 8.10 |
| 21 |  | M. Bumgarner | 2,070 | 358 | 134 | 124 | .519 | 355 | 3.47 | 16 | 7 | 0 | 2209.1 | 2,007 | 853 | 933 | 258 | 544 | 89 | 1 | 38 | 9,098 | 29 | 8.43 | 2.22 | 3.81 | 1.05 | 22.8 | 6.0 | 1.15 | .285 | 3.80 | 8.18 |
| 22 | | R. Halladay | 2,061 | 388 | 194 | 101 | .658 | 377 | 3.38 | 65 | 19 | 0 | 2638.0 | 2,534 | 991 | 1,083 | 223 | 538 | 79 | 4 | 28 | 10,796 | 52 | 7.03 | 1.84 | 3.83 | 0.76 | 19.1 | 5.0 | 1.16 | .293 | 3.69 | 8.65 |
| 23 | | L. Lynn | 2,015 | 364 | 143 | 99 | .591 | 340 | 3.74 | 4 | 2 | 1 | 2006.1 | 1,856 | 834 | 916 | 231 | 704 | 89 | 4 | 21 | 8,520 | 61 | 9.04 | 3.16 | 2.86 | 1.04 | 23.7 | 8.3 | 1.28 | .296 | 4.11 | 8.33 |
| 24 | | D. Haren | 2,013 | 391 | 153 | 131 | .539 | 380 | 3.75 | 16 | 6 | 1 | 2419.2 | 2,357 | 1,009 | 1,105 | 305 | 500 | 67 | 4 | 39 | 10,022 | 98 | 7.49 | 1.86 | 4.03 | 1.13 | 20.1 | 5.0 | 1.18 | .288 | 4.11 | 8.77 |
| 25 | | T. Hudson | 2,009 | 471 | 216 | 132 | .621 | 468 | 3.52 | 26 | 13 | 0 | 3052.2 | 2,893 | 1,193 | 1,298 | 246 | 885 | 121 | 0 | 84 | 12,698 | 82 | 5.92 | 2.61 | 2.27 | 0.73 | 15.8 | 7.0 | 1.24 | .280 | 3.83 | 8.53 |
StatMuse has game-level data for strikeouts going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
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