Between July 30, 1994 and August 22, 2025, Randy Johnson fanned the most hitters, with 3,566 strikeouts.
- Regular season
| NAME | SO | G | W | L | W% | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | H/9 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | R. Johnson | 3,566 | 432 | 224 | 104 | .683 | 419 | 3.11 | 66 | 25 | 1 | 2907.0 | 2,392 | 1,004 | 1,133 | 305 | 811 | 131 | 5 | 29 | 11,814 | 57 | 11.04 | 2.51 | 4.40 | 0.94 | 30.2 | 6.9 | 1.10 | .298 | 3.51 | 7.41 |
| 2 |  | J. Verlander | 3,515 | 548 | 263 | 157 | .626 | 548 | 3.34 | 26 | 9 | 0 | 3526.1 | 3,012 | 1,308 | 1,417 | 367 | 989 | 120 | 0 | 27 | 14,434 | 99 | 8.97 | 2.52 | 3.55 | 0.94 | 24.4 | 6.9 | 1.13 | .280 | 3.62 | 7.69 |
| 3 |  | M. Scherzer | 3,463 | 477 | 219 | 114 | .658 | 468 | 3.17 | 12 | 5 | 0 | 2938.0 | 2,396 | 1,034 | 1,107 | 346 | 771 | 114 | 2 | 20 | 11,869 | 79 | 10.61 | 2.36 | 4.49 | 1.06 | 29.2 | 6.5 | 1.08 | .286 | 3.39 | 7.34 |
| 4 |  | CC Sabathia | 3,093 | 561 | 251 | 161 | .609 | 560 | 3.74 | 38 | 12 | 0 | 3577.1 | 3,404 | 1,485 | 1,623 | 382 | 1,099 | 123 | 0 | 44 | 14,989 | 74 | 7.78 | 2.76 | 2.81 | 0.96 | 20.6 | 7.3 | 1.26 | .294 | 4.08 | 8.56 |
| 5 |  | C. Kershaw | 3,020 | 448 | 220 | 96 | .696 | 445 | 2.52 | 25 | 15 | 0 | 2826.0 | 2,170 | 791 | 868 | 234 | 699 | 46 | 1 | 28 | 11,155 | 107 | 9.62 | 2.23 | 4.32 | 0.75 | 27.1 | 6.3 | 1.02 | .271 | 2.76 | 6.91 |
| 6 |  | Z. Greinke | 2,979 | 586 | 225 | 156 | .591 | 541 | 3.49 | 17 | 5 | 1 | 3389.1 | 3,207 | 1,315 | 1,410 | 367 | 762 | 79 | 8 | 25 | 13,877 | 101 | 7.91 | 2.02 | 3.91 | 0.97 | 21.5 | 5.5 | 1.17 | .293 | 3.74 | 8.52 |
| 7 |  | P. Martinez | 2,903 | 388 | 201 | 89 | .693 | 386 | 2.89 | 45 | 16 | 0 | 2590.1 | 2,037 | 833 | 915 | 223 | 666 | 126 | 1 | 23 | 10,421 | 55 | 10.09 | 2.31 | 4.36 | 0.77 | 27.9 | 6.4 | 1.04 | .279 | 3.18 | 7.08 |
| 8 |  | C. Schilling | 2,621 | 383 | 181 | 110 | .622 | 361 | 3.43 | 66 | 14 | 9 | 2594.1 | 2,383 | 989 | 1,030 | 296 | 502 | 43 | 21 | 22 | 10,498 | 50 | 9.09 | 1.74 | 5.22 | 1.03 | 25.0 | 4.8 | 1.11 | .297 | 3.57 | 8.27 |
| 9 | | C. Hamels | 2,560 | 423 | 163 | 122 | .572 | 422 | 3.43 | 17 | 7 | 0 | 2698.0 | 2,424 | 1,027 | 1,103 | 310 | 767 | 100 | 0 | 43 | 11,115 | 57 | 8.54 | 2.56 | 3.34 | 1.03 | 23.0 | 6.9 | 1.18 | .287 | 3.68 | 8.09 |
| 10 | | J. Vazquez | 2,536 | 450 | 165 | 160 | .508 | 443 | 4.22 | 28 | 8 | 0 | 2840.0 | 2,784 | 1,331 | 1,431 | 373 | 763 | 88 | 5 | 58 | 11,935 | 76 | 8.04 | 2.42 | 3.32 | 1.18 | 21.2 | 6.4 | 1.25 | .295 | 4.53 | 8.82 |
| 11 |  | B. Colon | 2,535 | 565 | 247 | 188 | .568 | 552 | 4.12 | 38 | 13 | 0 | 3461.2 | 3,593 | 1,584 | 1,719 | 439 | 948 | 64 | 2 | 47 | 14,655 | 45 | 6.59 | 2.46 | 2.67 | 1.14 | 17.3 | 6.5 | 1.31 | .296 | 4.47 | 9.34 |
| 12 |  | C. Sale | 2,528 | 387 | 143 | 87 | .622 | 307 | 3.02 | 16 | 3 | 12 | 2047.2 | 1,668 | 686 | 739 | 209 | 481 | 126 | 25 | 15 | 8,249 | 47 | 11.11 | 2.11 | 5.26 | 0.92 | 30.6 | 5.8 | 1.05 | .297 | 3.25 | 7.33 |
| 13 |  | F. Hernandez | 2,524 | 419 | 169 | 136 | .554 | 418 | 3.42 | 25 | 11 | 0 | 2729.2 | 2,487 | 1,037 | 1,157 | 264 | 805 | 105 | 0 | 16 | 11,284 | 156 | 8.32 | 2.65 | 3.14 | 0.87 | 22.4 | 7.1 | 1.21 | .293 | 3.81 | 8.20 |
| 14 | | A.J. Burnett | 2,513 | 435 | 164 | 157 | .511 | 430 | 3.99 | 24 | 10 | 0 | 2731.1 | 2,519 | 1,210 | 1,328 | 263 | 1,100 | 143 | 1 | 35 | 11,665 | 161 | 8.28 | 3.62 | 2.28 | 0.87 | 21.5 | 9.4 | 1.32 | .295 | 4.38 | 8.30 |
| 15 |  | J. Lester | 2,488 | 452 | 200 | 117 | .631 | 451 | 3.66 | 15 | 4 | 0 | 2740.0 | 2,610 | 1,114 | 1,215 | 294 | 892 | 90 | 0 | 13 | 11,487 | 63 | 8.17 | 2.93 | 2.79 | 0.97 | 21.7 | 7.8 | 1.28 | .300 | 3.99 | 8.57 |
| 16 |  | R. Clemens | 2,487 | 386 | 182 | 93 | .662 | 385 | 3.31 | 24 | 10 | 0 | 2545.1 | 2,203 | 935 | 1,024 | 206 | 903 | 92 | 0 | 22 | 10,605 | 88 | 8.79 | 3.19 | 2.75 | 0.73 | 23.5 | 8.5 | 1.22 | .289 | 3.62 | 7.79 |
| 17 | | A. Pettitte | 2,448 | 531 | 256 | 153 | .626 | 521 | 3.85 | 26 | 4 | 0 | 3316.0 | 3,448 | 1,418 | 1,572 | 288 | 1,031 | 55 | 3 | 42 | 14,074 | 69 | 6.64 | 2.80 | 2.37 | 0.78 | 17.4 | 7.3 | 1.35 | .308 | 4.27 | 9.36 |
| 18 | | M. Mussina | 2,424 | 446 | 220 | 132 | .625 | 445 | 3.78 | 41 | 17 | 0 | 2905.0 | 2,855 | 1,221 | 1,313 | 314 | 633 | 53 | 0 | 24 | 11,937 | 57 | 7.51 | 1.96 | 3.83 | 0.97 | 20.3 | 5.3 | 1.20 | .298 | 4.07 | 8.85 |
| 19 | | J. Lackey | 2,294 | 448 | 188 | 147 | .561 | 446 | 3.92 | 18 | 8 | 0 | 2840.1 | 2,862 | 1,237 | 1,347 | 319 | 815 | 133 | 0 | 32 | 12,030 | 125 | 7.27 | 2.58 | 2.81 | 1.01 | 19.1 | 6.8 | 1.29 | .300 | 4.27 | 9.07 |
| 20 |  | G. Cole | 2,251 | 317 | 153 | 80 | .657 | 317 | 3.18 | 8 | 5 | 0 | 1954.0 | 1,627 | 690 | 740 | 217 | 500 | 61 | 0 | 7 | 7,861 | 58 | 10.37 | 2.30 | 4.50 | 1.00 | 28.6 | 6.4 | 1.09 | .292 | 3.41 | 7.49 |
| 21 | | J. Shields | 2,234 | 407 | 145 | 139 | .511 | 405 | 4.01 | 23 | 9 | 0 | 2616.0 | 2,581 | 1,167 | 1,267 | 361 | 746 | 97 | 1 | 22 | 10,993 | 107 | 7.69 | 2.57 | 2.99 | 1.24 | 20.3 | 6.8 | 1.27 | .294 | 4.36 | 8.88 |
| 22 | | J. Peavy | 2,207 | 388 | 152 | 126 | .547 | 377 | 3.63 | 15 | 6 | 0 | 2377.0 | 2,134 | 960 | 1,011 | 259 | 708 | 78 | 3 | 42 | 9,838 | 46 | 8.36 | 2.68 | 3.12 | 0.98 | 22.4 | 7.2 | 1.20 | .285 | 3.83 | 8.08 |
| 23 | | A. Wainwright | 2,202 | 478 | 200 | 128 | .610 | 411 | 3.53 | 28 | 11 | 3 | 2668.1 | 2,577 | 1,047 | 1,117 | 233 | 736 | 81 | 13 | 40 | 11,116 | 51 | 7.43 | 2.48 | 2.99 | 0.79 | 19.8 | 6.6 | 1.24 | .298 | 3.77 | 8.69 |
| 24 |  | C. Morton | 2,177 | 410 | 147 | 133 | .525 | 403 | 4.07 | 3 | 2 | 0 | 2249.1 | 2,117 | 1,018 | 1,117 | 222 | 843 | 198 | 1 | 27 | 9,659 | 70 | 8.71 | 3.37 | 2.58 | 0.89 | 22.5 | 8.7 | 1.32 | .305 | 4.47 | 8.47 |
| 25 | | R. Halladay | 2,117 | 416 | 203 | 105 | .659 | 390 | 3.38 | 67 | 20 | 1 | 2749.1 | 2,646 | 1,034 | 1,135 | 236 | 592 | 81 | 6 | 28 | 11,287 | 56 | 6.93 | 1.94 | 3.58 | 0.77 | 18.8 | 5.2 | 1.18 | .292 | 3.72 | 8.66 |
StatMuse has game-level data for strikeouts going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
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88 | 63 | .583 | ||
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