Between June 21, 1968 and August 31, 2005, Nolan Ryan fanned the most hitters, with 5,611 strikeouts.
| NAME | SO | G | W | L | W% | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | H/9 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | N. Ryan | 5,611 | 793 | 319 | 286 | .527 | 760 | 3.20 | 219 | 61 | 3 | 5296.2 | 3,861 | 1,886 | 2,149 | 315 | 2,745 | 155 | 13 | 75 | 22,200 | 271 | 9.53 | 4.66 | 2.04 | 0.54 | 25.3 | 12.4 | 1.25 | .265 | 3.65 | 6.56 |
| 2 |  | R. Clemens | 4,484 | 667 | 339 | 170 | .666 | 666 | 3.12 | 118 | 46 | 0 | 4677.1 | 3,966 | 1,619 | 1,784 | 344 | 1,507 | 149 | 0 | 59 | 19,244 | 131 | 8.63 | 2.90 | 2.98 | 0.66 | 23.3 | 7.8 | 1.17 | .284 | 3.43 | 7.63 |
| 3 |  | R. Johnson | 4,341 | 517 | 259 | 136 | .656 | 507 | 3.12 | 96 | 37 | 2 | 3557.1 | 2,797 | 1,233 | 1,395 | 330 | 1,338 | 166 | 5 | 25 | 14,642 | 98 | 10.98 | 3.39 | 3.24 | 0.83 | 29.6 | 9.1 | 1.16 | .291 | 3.53 | 7.08 |
| 4 |  | S. Carlton | 3,842 | 672 | 304 | 230 | .569 | 656 | 3.25 | 234 | 48 | 1 | 4835.1 | 4,327 | 1,746 | 1,999 | 397 | 1,720 | 48 | 6 | 146 | 20,106 | 167 | 7.15 | 3.20 | 2.23 | 0.74 | 19.1 | 8.6 | 1.25 | .279 | 3.72 | 8.05 |
| 5 |  | B. Blyleven | 3,701 | 692 | 287 | 250 | .534 | 685 | 3.31 | 242 | 60 | 0 | 4970.0 | 4,632 | 1,830 | 2,029 | 430 | 1,322 | 155 | 3 | 71 | 20,492 | 114 | 6.70 | 2.39 | 2.80 | 0.78 | 18.1 | 6.5 | 1.20 | .282 | 3.67 | 8.39 |
| 6 |  | T. Seaver | 3,393 | 606 | 290 | 187 | .608 | 598 | 2.89 | 208 | 58 | 1 | 4408.1 | 3,643 | 1,414 | 1,555 | 355 | 1,290 | 67 | 5 | 108 | 17,844 | 116 | 6.93 | 2.63 | 2.63 | 0.72 | 19.0 | 7.2 | 1.12 | .258 | 3.17 | 7.44 |
| 7 | | D. Sutton | 3,135 | 687 | 298 | 222 | .573 | 674 | 3.23 | 159 | 53 | 4 | 4741.0 | 4,195 | 1,704 | 1,882 | 430 | 1,207 | 72 | 10 | 83 | 19,399 | 103 | 5.95 | 2.29 | 2.60 | 0.82 | 16.2 | 6.2 | 1.14 | .259 | 3.57 | 7.96 |
| 8 | | P. Niekro | 3,089 | 724 | 296 | 253 | .539 | 682 | 3.40 | 231 | 43 | 11 | 4964.1 | 4,659 | 1,874 | 2,158 | 454 | 1,669 | 105 | 28 | 75 | 20,852 | 186 | 5.60 | 3.03 | 1.85 | 0.82 | 14.8 | 8.0 | 1.27 | .271 | 3.91 | 8.45 |
| 9 |  | G. Maddux | 3,022 | 636 | 315 | 185 | .630 | 632 | 3.01 | 107 | 35 | 0 | 4360.0 | 4,033 | 1,458 | 1,655 | 293 | 901 | 125 | 3 | 161 | 17,734 | 62 | 6.24 | 1.86 | 3.35 | 0.60 | 17.0 | 5.1 | 1.13 | .279 | 3.42 | 8.33 |
| 10 |  | P. Martinez | 2,841 | 415 | 195 | 82 | .704 | 348 | 2.72 | 45 | 16 | 3 | 2485.0 | 1,880 | 752 | 828 | 194 | 654 | 118 | 23 | 22 | 9,922 | 57 | 10.29 | 2.37 | 4.34 | 0.70 | 28.6 | 6.6 | 1.02 | .276 | 3.00 | 6.81 |
| 11 | | C. Schilling | 2,801 | 508 | 189 | 129 | .594 | 375 | 3.39 | 82 | 19 | 22 | 2865.2 | 2,564 | 1,080 | 1,142 | 294 | 649 | 47 | 81 | 41 | 11,640 | 70 | 8.80 | 2.04 | 4.32 | 0.92 | 24.1 | 5.6 | 1.12 | .289 | 3.59 | 8.05 |
| 12 | | F. Tanana | 2,773 | 638 | 240 | 236 | .504 | 616 | 3.66 | 143 | 34 | 1 | 4188.1 | 4,063 | 1,702 | 1,910 | 448 | 1,255 | 129 | 10 | 116 | 17,641 | 119 | 5.96 | 2.70 | 2.21 | 0.96 | 15.7 | 7.1 | 1.27 | .277 | 4.10 | 8.73 |
| 13 | | F. Jenkins | 2,694 | 542 | 250 | 196 | .561 | 528 | 3.41 | 239 | 44 | 1 | 3895.0 | 3,670 | 1,477 | 1,639 | 418 | 834 | 77 | 9 | 94 | 15,987 | 57 | 6.22 | 1.93 | 3.23 | 0.97 | 16.9 | 5.2 | 1.16 | .272 | 3.79 | 8.48 |
| 14 | | D. Cone | 2,668 | 450 | 194 | 126 | .606 | 419 | 3.47 | 56 | 22 | 1 | 2898.2 | 2,504 | 1,116 | 1,222 | 258 | 1,137 | 106 | 9 | 42 | 12,184 | 149 | 8.28 | 3.53 | 2.35 | 0.80 | 21.9 | 9.3 | 1.26 | .280 | 3.79 | 7.77 |
| 15 | | G. Perry | 2,631 | 551 | 248 | 206 | .546 | 546 | 3.07 | 257 | 44 | 2 | 4174.1 | 3,853 | 1,423 | 1,655 | 309 | 1,070 | 86 | 5 | 107 | 17,086 | 116 | 5.67 | 2.31 | 2.46 | 0.67 | 15.4 | 6.3 | 1.18 | .273 | 3.57 | 8.31 |
| 16 | | C. Finley | 2,610 | 524 | 200 | 173 | .536 | 467 | 3.85 | 63 | 15 | 0 | 3197.1 | 3,069 | 1,366 | 1,517 | 304 | 1,332 | 76 | 24 | 36 | 13,638 | 130 | 7.35 | 3.75 | 1.96 | 0.86 | 19.1 | 9.8 | 1.38 | .297 | 4.27 | 8.64 |
| 17 |  | J. Smoltz | 2,547 | 630 | 176 | 127 | .581 | 389 | 3.25 | 50 | 15 | 154 | 2897.1 | 2,505 | 1,047 | 1,144 | 230 | 877 | 40 | 204 | 67 | 11,868 | 130 | 7.91 | 2.72 | 2.90 | 0.71 | 21.5 | 7.4 | 1.17 | .278 | 3.55 | 7.78 |
| 18 |  | J. Morris | 2,478 | 549 | 254 | 186 | .577 | 527 | 3.90 | 175 | 28 | 0 | 3824.0 | 3,567 | 1,657 | 1,815 | 389 | 1,390 | 58 | 10 | 99 | 16,120 | 205 | 5.83 | 3.27 | 1.78 | 0.92 | 15.4 | 8.6 | 1.30 | .269 | 4.27 | 8.40 |
| 19 | | M. Langston | 2,464 | 457 | 179 | 158 | .531 | 428 | 3.97 | 81 | 18 | 0 | 2962.2 | 2,723 | 1,306 | 1,438 | 311 | 1,289 | 46 | 3 | 34 | 12,562 | 89 | 7.49 | 3.92 | 1.91 | 0.94 | 19.6 | 10.3 | 1.35 | .285 | 4.37 | 8.27 |
| 20 | | J. Koosman | 2,461 | 589 | 211 | 205 | .507 | 510 | 3.40 | 132 | 30 | 17 | 3703.2 | 3,529 | 1,399 | 1,568 | 283 | 1,153 | 70 | 42 | 117 | 15,453 | 83 | 5.98 | 2.80 | 2.13 | 0.69 | 15.9 | 7.5 | 1.26 | .283 | 3.81 | 8.58 |
| 21 | | D. Eckersley | 2,401 | 1,071 | 197 | 171 | .535 | 361 | 3.50 | 100 | 20 | 390 | 3285.2 | 3,076 | 1,279 | 1,382 | 347 | 738 | 75 | 577 | 90 | 13,534 | 28 | 6.58 | 2.02 | 3.25 | 0.95 | 17.7 | 5.5 | 1.16 | .274 | 3.79 | 8.43 |
| 22 | | K. Brown | 2,397 | 486 | 211 | 144 | .594 | 476 | 3.28 | 72 | 17 | 0 | 3256.1 | 3,079 | 1,185 | 1,357 | 208 | 901 | 139 | 1 | 42 | 13,542 | 108 | 6.62 | 2.49 | 2.66 | 0.57 | 17.7 | 6.7 | 1.22 | .290 | 3.75 | 8.51 |
| 23 | | M. Mussina | 2,393 | 441 | 223 | 127 | .637 | 441 | 3.64 | 56 | 23 | 0 | 3005.1 | 2,863 | 1,214 | 1,290 | 323 | 683 | 42 | 0 | 23 | 12,277 | 63 | 7.17 | 2.05 | 3.50 | 0.97 | 19.5 | 5.6 | 1.18 | .287 | 3.86 | 8.57 |
| 24 | | C. Hough | 2,362 | 858 | 216 | 216 | .500 | 440 | 3.75 | 107 | 13 | 61 | 3801.1 | 3,283 | 1,582 | 1,807 | 383 | 1,664 | 174 | 240 | 44 | 16,168 | 180 | 5.59 | 3.94 | 1.42 | 0.91 | 14.6 | 10.3 | 1.30 | .250 | 4.28 | 7.77 |
| 25 | | T. Glavine | 2,316 | 597 | 272 | 182 | .599 | 597 | 3.46 | 53 | 23 | 0 | 3904.1 | 3,782 | 1,503 | 1,655 | 299 | 1,325 | 55 | 0 | 131 | 16,448 | 62 | 5.34 | 3.05 | 1.75 | 0.69 | 14.1 | 8.1 | 1.31 | .280 | 3.81 | 8.72 |
StatMuse has game-level data for strikeouts going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
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| NL East | W | L | PCT | GB |
|---|---|---|---|---|
 Braves - y | 94 | 68 | .580 | |
 Phillies - w | 88 | 74 | .543 | 6.0 |
80 | 82 | .494 | 14.0 | |
77 | 85 | .475 | 17.0 | |
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| NL Central | W | L | PCT | GB |
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 Cubs - w | 89 | 73 | .549 | 14.0 |
82 | 80 | .506 | 21.0 | |
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| NL West | W | L | PCT | GB |
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|---|---|---|---|---|
 Rays - y | 98 | 64 | .605 | |
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| AL Central | W | L | PCT | GB |
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| AL West | W | L | PCT | GB |
 Astros - y | 81 | 81 | .500 | |
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