Between May 26, 1967 and July 21, 2007, Nolan Ryan struck out the most hitters, with 5,708 strikeouts.
| NAME | SO | G | W | L | W% | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | H/9 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | N. Ryan | 5,708 | 805 | 324 | 291 | .527 | 772 | 3.19 | 222 | 61 | 3 | 5383.0 | 3,918 | 1,906 | 2,173 | 320 | 2,792 | 158 | 13 | 77 | 22,558 | 276 | 9.54 | 4.67 | 2.04 | 0.54 | 25.3 | 12.4 | 1.25 | .265 | 3.63 | 6.55 |
| 2 |  | R. Clemens | 4,638 | 700 | 350 | 182 | .658 | 698 | 3.11 | 118 | 46 | 0 | 4868.2 | 4,134 | 1,683 | 1,855 | 358 | 1,564 | 154 | 0 | 63 | 20,030 | 140 | 8.57 | 2.89 | 2.97 | 0.66 | 23.2 | 7.8 | 1.17 | .284 | 3.43 | 7.64 |
| 3 |  | R. Johnson | 4,616 | 566 | 284 | 150 | .654 | 556 | 3.22 | 98 | 37 | 2 | 3855.1 | 3,065 | 1,381 | 1,556 | 368 | 1,422 | 182 | 5 | 29 | 15,877 | 102 | 10.78 | 3.32 | 3.25 | 0.86 | 29.1 | 9.0 | 1.16 | .290 | 3.63 | 7.16 |
| 4 |  | S. Carlton | 4,064 | 711 | 324 | 240 | .574 | 694 | 3.22 | 252 | 54 | 1 | 5113.2 | 4,561 | 1,830 | 2,090 | 407 | 1,799 | 52 | 7 | 148 | 21,241 | 174 | 7.15 | 3.17 | 2.26 | 0.72 | 19.1 | 8.5 | 1.24 | .278 | 3.68 | 8.03 |
| 5 |  | B. Blyleven | 3,701 | 692 | 287 | 250 | .534 | 685 | 3.31 | 242 | 60 | 0 | 4970.0 | 4,632 | 1,830 | 2,029 | 430 | 1,322 | 155 | 3 | 71 | 20,492 | 114 | 6.70 | 2.39 | 2.80 | 0.78 | 18.1 | 6.5 | 1.20 | .282 | 3.67 | 8.39 |
| 6 |  | T. Seaver | 3,602 | 648 | 307 | 203 | .602 | 639 | 2.87 | 227 | 61 | 1 | 4725.1 | 3,919 | 1,505 | 1,657 | 373 | 1,374 | 74 | 6 | 117 | 19,132 | 122 | 6.86 | 2.62 | 2.62 | 0.71 | 18.8 | 7.2 | 1.12 | .259 | 3.16 | 7.46 |
| 7 | | D. Sutton | 3,328 | 728 | 311 | 239 | .565 | 712 | 3.26 | 171 | 55 | 5 | 4998.2 | 4,438 | 1,810 | 1,989 | 449 | 1,273 | 76 | 12 | 97 | 20,467 | 107 | 5.99 | 2.29 | 2.61 | 0.81 | 16.3 | 6.2 | 1.14 | .260 | 3.58 | 7.99 |
| 8 | | P. Niekro | 3,247 | 767 | 311 | 266 | .539 | 715 | 3.36 | 245 | 45 | 15 | 5228.0 | 4,877 | 1,950 | 2,251 | 470 | 1,741 | 116 | 36 | 77 | 21,914 | 212 | 5.59 | 3.00 | 1.87 | 0.81 | 14.8 | 7.9 | 1.27 | .270 | 3.88 | 8.40 |
| 9 |  | G. Maddux | 3,235 | 697 | 340 | 210 | .618 | 693 | 3.10 | 109 | 35 | 0 | 4735.0 | 4,435 | 1,630 | 1,841 | 327 | 963 | 129 | 3 | 172 | 19,290 | 66 | 6.15 | 1.83 | 3.36 | 0.62 | 16.8 | 5.0 | 1.14 | .281 | 3.50 | 8.43 |
| 10 | | C. Schilling | 3,086 | 560 | 213 | 142 | .600 | 427 | 3.46 | 83 | 20 | 22 | 3204.1 | 2,942 | 1,232 | 1,296 | 338 | 707 | 52 | 81 | 43 | 13,055 | 72 | 8.67 | 1.99 | 4.36 | 0.95 | 23.6 | 5.4 | 1.14 | .294 | 3.64 | 8.26 |
| 11 |  | P. Martinez | 2,998 | 442 | 206 | 92 | .691 | 375 | 2.81 | 46 | 17 | 3 | 2645.2 | 2,013 | 825 | 907 | 213 | 701 | 129 | 23 | 26 | 10,582 | 59 | 10.20 | 2.38 | 4.28 | 0.72 | 28.3 | 6.6 | 1.03 | .275 | 3.09 | 6.85 |
| 12 | | F. Jenkins | 2,987 | 586 | 272 | 214 | .560 | 572 | 3.34 | 261 | 47 | 1 | 4239.1 | 3,932 | 1,575 | 1,750 | 452 | 920 | 80 | 9 | 103 | 17,345 | 60 | 6.34 | 1.95 | 3.25 | 0.96 | 17.2 | 5.3 | 1.14 | .270 | 3.72 | 8.35 |
| 13 |  | J. Smoltz | 2,885 | 688 | 202 | 142 | .587 | 447 | 3.26 | 53 | 16 | 154 | 3274.0 | 2,871 | 1,186 | 1,288 | 266 | 961 | 52 | 204 | 78 | 13,430 | 140 | 7.93 | 2.64 | 3.00 | 0.73 | 21.5 | 7.2 | 1.17 | .281 | 3.54 | 7.89 |
| 14 | | G. Perry | 2,882 | 596 | 267 | 223 | .545 | 589 | 3.04 | 275 | 47 | 3 | 4501.1 | 4,118 | 1,521 | 1,767 | 326 | 1,171 | 89 | 7 | 128 | 18,412 | 127 | 5.76 | 2.34 | 2.46 | 0.65 | 15.7 | 6.4 | 1.17 | .272 | 3.53 | 8.23 |
| 15 | | F. Tanana | 2,773 | 638 | 240 | 236 | .504 | 616 | 3.66 | 143 | 34 | 1 | 4188.1 | 4,063 | 1,702 | 1,910 | 448 | 1,255 | 129 | 10 | 116 | 17,641 | 119 | 5.96 | 2.70 | 2.21 | 0.96 | 15.7 | 7.1 | 1.27 | .277 | 4.10 | 8.73 |
| 16 | | D. Cone | 2,668 | 450 | 194 | 126 | .606 | 419 | 3.47 | 56 | 22 | 1 | 2898.2 | 2,504 | 1,116 | 1,222 | 258 | 1,137 | 106 | 9 | 42 | 12,184 | 149 | 8.28 | 3.53 | 2.35 | 0.80 | 21.9 | 9.3 | 1.26 | .280 | 3.79 | 7.77 |
| 17 | | M. Mussina | 2,626 | 491 | 243 | 141 | .633 | 491 | 3.67 | 57 | 23 | 0 | 3299.0 | 3,159 | 1,345 | 1,435 | 356 | 741 | 51 | 0 | 26 | 13,495 | 66 | 7.16 | 2.02 | 3.54 | 0.97 | 19.5 | 5.5 | 1.18 | .288 | 3.91 | 8.62 |
| 18 | | C. Finley | 2,610 | 524 | 200 | 173 | .536 | 467 | 3.85 | 63 | 15 | 0 | 3197.1 | 3,069 | 1,366 | 1,517 | 304 | 1,332 | 76 | 24 | 36 | 13,638 | 130 | 7.35 | 3.75 | 1.96 | 0.86 | 19.1 | 9.8 | 1.38 | .297 | 4.27 | 8.64 |
| 19 | | J. Koosman | 2,553 | 607 | 222 | 209 | .515 | 527 | 3.36 | 140 | 33 | 17 | 3830.0 | 3,626 | 1,428 | 1,601 | 289 | 1,190 | 71 | 42 | 118 | 15,950 | 89 | 6.00 | 2.80 | 2.15 | 0.68 | 16.0 | 7.5 | 1.26 | .282 | 3.76 | 8.52 |
| 20 | | T. Glavine | 2,539 | 656 | 298 | 197 | .602 | 656 | 3.49 | 56 | 25 | 0 | 4275.1 | 4,143 | 1,659 | 1,824 | 339 | 1,440 | 64 | 0 | 141 | 17,999 | 64 | 5.34 | 3.03 | 1.76 | 0.71 | 14.1 | 8.0 | 1.31 | .279 | 3.84 | 8.72 |
| 21 |  | J. Morris | 2,478 | 549 | 254 | 186 | .577 | 527 | 3.90 | 175 | 28 | 0 | 3824.0 | 3,567 | 1,657 | 1,815 | 389 | 1,390 | 58 | 10 | 99 | 16,120 | 205 | 5.83 | 3.27 | 1.78 | 0.92 | 15.4 | 8.6 | 1.30 | .269 | 4.27 | 8.40 |
| 22 | | M. Langston | 2,464 | 457 | 179 | 158 | .531 | 428 | 3.97 | 81 | 18 | 0 | 2962.2 | 2,723 | 1,306 | 1,438 | 311 | 1,289 | 46 | 3 | 34 | 12,562 | 89 | 7.49 | 3.92 | 1.91 | 0.94 | 19.6 | 10.3 | 1.35 | .285 | 4.37 | 8.27 |
| 23 | | D. Eckersley | 2,401 | 1,071 | 197 | 171 | .535 | 361 | 3.50 | 100 | 20 | 390 | 3285.2 | 3,076 | 1,279 | 1,382 | 347 | 738 | 75 | 577 | 90 | 13,534 | 28 | 6.58 | 2.02 | 3.25 | 0.95 | 17.7 | 5.5 | 1.16 | .274 | 3.79 | 8.43 |
| 24 | | K. Brown | 2,397 | 486 | 211 | 144 | .594 | 476 | 3.28 | 72 | 17 | 0 | 3256.1 | 3,079 | 1,185 | 1,357 | 208 | 901 | 139 | 1 | 42 | 13,542 | 108 | 6.62 | 2.49 | 2.66 | 0.57 | 17.7 | 6.7 | 1.22 | .290 | 3.75 | 8.51 |
| 25 | | C. Hough | 2,362 | 858 | 216 | 216 | .500 | 440 | 3.75 | 107 | 13 | 61 | 3801.1 | 3,283 | 1,582 | 1,807 | 383 | 1,664 | 174 | 240 | 44 | 16,168 | 180 | 5.59 | 3.94 | 1.42 | 0.91 | 14.6 | 10.3 | 1.30 | .250 | 4.28 | 7.77 |
StatMuse has game-level data for strikeouts going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
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| NL East | W | L | PCT | GB |
|---|---|---|---|---|
 Braves - y | 94 | 68 | .580 | |
 Phillies - w | 88 | 74 | .543 | 6.0 |
80 | 82 | .494 | 14.0 | |
77 | 85 | .475 | 17.0 | |
74 | 88 | .457 | 20.0 | |
| NL Central | W | L | PCT | GB |
 Brewers - y | 103 | 59 | .636 | |
 Cubs - w | 89 | 73 | .549 | 14.0 |
82 | 80 | .506 | 21.0 | |
77 | 85 | .475 | 26.0 | |
75 | 87 | .463 | 28.0 | |
| NL West | W | L | PCT | GB |
 Dodgers - y | 100 | 62 | .617 | |
 Padres - w | 91 | 71 | .562 | 9.0 |
86 | 76 | .531 | 14.0 | |
65 | 97 | .401 | 35.0 | |
58 | 104 | .358 | 42.0 |
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Diamondbacks
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|---|---|---|---|---|
 Rays - y | 98 | 64 | .605 | |
 Yankees - w | 93 | 68 | .578 | 4.5 |
 Red Sox - w | 87 | 75 | .537 | 11.0 |
79 | 82 | .491 | 18.5 | |
79 | 83 | .488 | 19.0 | |
| AL Central | W | L | PCT | GB |
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 White Sox - w | 84 | 78 | .519 | 1.0 |
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76 | 86 | .469 | 9.0 | |
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| AL West | W | L | PCT | GB |
 Astros - y | 81 | 81 | .500 | |
80 | 82 | .494 | 1.0 | |
76 | 86 | .469 | 5.0 | |
64 | 98 | .395 | 17.0 | |
62 | 100 | .383 | 19.0 |
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