Between July 17, 1984 and October 1, 2007, Randy Johnson fanned the most batters, with 4,616 strikeouts.
- Regular season
| NAME | SO | G | W | L | W% | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | H/9 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | R. Johnson | 4,616 | 566 | 284 | 150 | .654 | 556 | 3.22 | 98 | 37 | 2 | 3855.1 | 3,065 | 1,381 | 1,556 | 368 | 1,422 | 182 | 5 | 29 | 15,877 | 102 | 10.78 | 3.32 | 3.25 | 0.86 | 29.1 | 9.0 | 1.16 | .290 | 3.63 | 7.16 |
| 2 |  | R. Clemens | 4,615 | 697 | 351 | 180 | .661 | 695 | 3.08 | 117 | 46 | 0 | 4847.0 | 4,088 | 1,661 | 1,837 | 354 | 1,566 | 157 | 0 | 61 | 19,922 | 141 | 8.57 | 2.91 | 2.95 | 0.66 | 23.2 | 7.9 | 1.17 | .282 | 3.41 | 7.59 |
| 3 |  | G. Maddux | 3,273 | 711 | 347 | 214 | .619 | 707 | 3.11 | 109 | 35 | 0 | 4814.1 | 4,522 | 1,665 | 1,876 | 332 | 969 | 131 | 3 | 172 | 19,617 | 68 | 6.12 | 1.81 | 3.38 | 0.62 | 16.7 | 4.9 | 1.14 | .281 | 3.51 | 8.45 |
| 4 |  | C. Schilling | 3,116 | 569 | 216 | 146 | .597 | 436 | 3.46 | 83 | 20 | 22 | 3261.0 | 2,998 | 1,253 | 1,318 | 347 | 711 | 52 | 81 | 43 | 13,284 | 72 | 8.60 | 1.96 | 4.38 | 0.96 | 23.5 | 5.4 | 1.14 | .293 | 3.64 | 8.27 |
| 5 |  | P. Martinez | 3,030 | 447 | 209 | 93 | .692 | 380 | 2.80 | 46 | 17 | 3 | 2673.2 | 2,046 | 833 | 918 | 213 | 708 | 131 | 23 | 27 | 10,710 | 60 | 10.20 | 2.38 | 4.28 | 0.72 | 28.3 | 6.6 | 1.03 | .277 | 3.09 | 6.89 |
| 6 |  | J. Smoltz | 2,975 | 702 | 207 | 145 | .588 | 461 | 3.26 | 53 | 16 | 154 | 3367.0 | 2,954 | 1,221 | 1,328 | 275 | 984 | 54 | 204 | 81 | 13,810 | 143 | 7.95 | 2.63 | 3.02 | 0.74 | 21.5 | 7.1 | 1.17 | .281 | 3.55 | 7.90 |
| 7 | | D. Cone | 2,668 | 450 | 194 | 126 | .606 | 419 | 3.47 | 56 | 22 | 1 | 2898.2 | 2,504 | 1,116 | 1,222 | 258 | 1,137 | 106 | 9 | 42 | 12,184 | 149 | 8.28 | 3.53 | 2.35 | 0.80 | 21.9 | 9.3 | 1.26 | .280 | 3.79 | 7.77 |
| 8 | | M. Mussina | 2,663 | 503 | 250 | 144 | .635 | 502 | 3.70 | 57 | 23 | 0 | 3362.1 | 3,246 | 1,383 | 1,474 | 359 | 754 | 52 | 0 | 26 | 13,774 | 67 | 7.13 | 2.02 | 3.53 | 0.96 | 19.3 | 5.5 | 1.19 | .290 | 3.95 | 8.69 |
| 9 | | C. Finley | 2,610 | 524 | 200 | 173 | .536 | 467 | 3.85 | 63 | 15 | 0 | 3197.1 | 3,069 | 1,366 | 1,517 | 304 | 1,332 | 76 | 24 | 36 | 13,638 | 130 | 7.35 | 3.75 | 1.96 | 0.86 | 19.1 | 9.8 | 1.38 | .297 | 4.27 | 8.64 |
| 10 | | T. Glavine | 2,570 | 669 | 303 | 199 | .604 | 669 | 3.51 | 56 | 25 | 0 | 4350.0 | 4,231 | 1,695 | 1,860 | 345 | 1,463 | 65 | 0 | 141 | 18,323 | 65 | 5.32 | 3.03 | 1.76 | 0.71 | 14.0 | 8.0 | 1.31 | .280 | 3.85 | 8.75 |
| 11 | | K. Brown | 2,397 | 486 | 211 | 144 | .594 | 476 | 3.28 | 72 | 17 | 0 | 3256.1 | 3,079 | 1,185 | 1,357 | 208 | 901 | 139 | 1 | 42 | 13,542 | 108 | 6.62 | 2.49 | 2.66 | 0.57 | 17.7 | 6.7 | 1.22 | .290 | 3.75 | 8.51 |
| 12 | | M. Langston | 2,373 | 437 | 172 | 151 | .533 | 410 | 3.98 | 78 | 16 | 0 | 2844.1 | 2,618 | 1,258 | 1,381 | 302 | 1,233 | 41 | 3 | 32 | 12,055 | 87 | 7.51 | 3.90 | 1.92 | 0.96 | 19.7 | 10.2 | 1.35 | .286 | 4.37 | 8.28 |
| 13 | | D. Wells | 2,201 | 660 | 239 | 157 | .604 | 489 | 4.13 | 54 | 12 | 13 | 3439.0 | 3,635 | 1,578 | 1,702 | 407 | 719 | 83 | 65 | 65 | 14,413 | 101 | 5.76 | 1.88 | 3.06 | 1.07 | 15.3 | 5.0 | 1.27 | .293 | 4.45 | 9.51 |
| 14 | | D. Gooden | 2,150 | 412 | 186 | 106 | .637 | 392 | 3.53 | 66 | 23 | 3 | 2682.2 | 2,471 | 1,051 | 1,152 | 206 | 906 | 77 | 4 | 41 | 11,213 | 75 | 7.21 | 3.04 | 2.37 | 0.69 | 19.2 | 8.1 | 1.26 | .288 | 3.86 | 8.29 |
| 15 | | J. Moyer | 2,125 | 604 | 230 | 178 | .564 | 551 | 4.21 | 31 | 9 | 0 | 3550.1 | 3,677 | 1,662 | 1,796 | 444 | 1,012 | 117 | 14 | 62 | 15,102 | 53 | 5.39 | 2.57 | 2.10 | 1.13 | 14.1 | 6.7 | 1.32 | .283 | 4.55 | 9.32 |
| 16 | | A. Benes | 2,000 | 403 | 155 | 139 | .527 | 387 | 3.97 | 21 | 9 | 1 | 2505.1 | 2,377 | 1,106 | 1,206 | 289 | 909 | 55 | 6 | 52 | 10,645 | 63 | 7.18 | 3.27 | 2.20 | 1.04 | 18.8 | 8.5 | 1.31 | .282 | 4.33 | 8.54 |
| 17 | | K. Appier | 1,994 | 414 | 169 | 137 | .552 | 402 | 3.74 | 34 | 12 | 0 | 2595.1 | 2,425 | 1,078 | 1,168 | 232 | 933 | 79 | 2 | 51 | 10,958 | 106 | 6.91 | 3.24 | 2.14 | 0.80 | 18.2 | 8.5 | 1.29 | .284 | 4.05 | 8.41 |
| 18 | | A. Leiter | 1,974 | 419 | 162 | 132 | .551 | 382 | 3.80 | 16 | 10 | 2 | 2391.0 | 2,152 | 1,010 | 1,101 | 198 | 1,163 | 117 | 9 | 53 | 10,334 | 63 | 7.43 | 4.38 | 1.70 | 0.75 | 19.1 | 11.3 | 1.39 | .284 | 4.14 | 8.10 |
| 19 | | B. Witt | 1,955 | 430 | 142 | 157 | .475 | 397 | 4.83 | 47 | 11 | 0 | 2465.0 | 2,493 | 1,324 | 1,449 | 252 | 1,375 | 39 | 13 | 37 | 11,003 | 128 | 7.14 | 5.02 | 1.42 | 0.92 | 17.8 | 12.5 | 1.57 | .304 | 5.29 | 9.10 |
| 20 | | O. Hershiser | 1,930 | 472 | 199 | 147 | .575 | 461 | 3.49 | 65 | 23 | 2 | 3042.0 | 2,853 | 1,180 | 1,331 | 228 | 976 | 116 | 5 | 102 | 12,774 | 118 | 5.71 | 2.89 | 1.98 | 0.67 | 15.1 | 7.6 | 1.26 | .276 | 3.94 | 8.44 |
| 21 |  | N. Ryan | 1,929 | 275 | 98 | 92 | .516 | 275 | 3.37 | 26 | 7 | 0 | 1768.0 | 1,324 | 662 | 753 | 124 | 734 | 59 | 0 | 27 | 7,327 | 101 | 9.82 | 3.74 | 2.63 | 0.63 | 26.3 | 10.0 | 1.16 | .268 | 3.83 | 6.74 |
| 22 | | H. Nomo | 1,915 | 320 | 123 | 109 | .530 | 318 | 4.21 | 16 | 9 | 0 | 1972.0 | 1,758 | 923 | 984 | 248 | 904 | 38 | 0 | 31 | 8,435 | 109 | 8.74 | 4.13 | 2.12 | 1.13 | 22.7 | 10.7 | 1.35 | .283 | 4.49 | 8.02 |
| 23 | | T. Gordon | 1,902 | 853 | 133 | 121 | .524 | 203 | 3.93 | 18 | 4 | 156 | 2076.2 | 1,855 | 906 | 993 | 173 | 957 | 38 | 339 | 56 | 8,909 | 106 | 8.24 | 4.15 | 1.99 | 0.75 | 21.3 | 10.7 | 1.35 | .288 | 4.30 | 8.04 |
| 24 | | K. Rogers | 1,886 | 732 | 210 | 143 | .595 | 444 | 4.19 | 36 | 9 | 28 | 3129.0 | 3,245 | 1,458 | 1,621 | 317 | 1,104 | 118 | 133 | 50 | 13,498 | 75 | 5.42 | 3.18 | 1.71 | 0.91 | 14.0 | 8.2 | 1.39 | .291 | 4.66 | 9.33 |
| 25 | | A. Pettitte | 1,844 | 403 | 201 | 113 | .640 | 393 | 3.83 | 25 | 4 | 0 | 2527.2 | 2,636 | 1,077 | 1,196 | 211 | 790 | 37 | 3 | 33 | 10,736 | 51 | 6.57 | 2.81 | 2.33 | 0.75 | 17.2 | 7.4 | 1.36 | .309 | 4.26 | 9.39 |
StatMuse has game-level data for strikeouts going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
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