Between August 11, 1993 and September 28, 2014, Randy Johnson struck out the most batters, with 3,856 strikeouts.
- Regular season
| NAME | SO | G | W | L | W% | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | H/9 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | R. Johnson | 3,856 | 464 | 243 | 110 | .688 | 450 | 3.09 | 78 | 30 | 2 | 3147.1 | 2,567 | 1,082 | 1,215 | 323 | 904 | 140 | 6 | 31 | 12,782 | 63 | 11.03 | 2.59 | 4.27 | 0.92 | 30.2 | 7.1 | 1.10 | .297 | 3.47 | 7.34 |
| 2 |  | P. Martinez | 3,067 | 429 | 210 | 97 | .684 | 408 | 2.94 | 46 | 17 | 1 | 2745.2 | 2,169 | 898 | 984 | 235 | 719 | 140 | 10 | 26 | 11,060 | 62 | 10.05 | 2.36 | 4.27 | 0.77 | 27.7 | 6.5 | 1.05 | .280 | 3.23 | 7.11 |
| 3 |  | C. Schilling | 2,739 | 403 | 188 | 118 | .614 | 381 | 3.47 | 67 | 14 | 9 | 2724.0 | 2,525 | 1,051 | 1,096 | 311 | 541 | 47 | 21 | 28 | 11,061 | 57 | 9.05 | 1.79 | 5.06 | 1.03 | 24.8 | 4.9 | 1.13 | .298 | 3.62 | 8.34 |
| 4 |  | R. Clemens | 2,673 | 416 | 193 | 104 | .650 | 415 | 3.35 | 27 | 11 | 0 | 2748.2 | 2,364 | 1,022 | 1,121 | 223 | 987 | 101 | 0 | 25 | 11,448 | 93 | 8.75 | 3.23 | 2.71 | 0.73 | 23.3 | 8.6 | 1.22 | .287 | 3.67 | 7.74 |
| 5 | | M. Mussina | 2,540 | 474 | 237 | 139 | .630 | 473 | 3.76 | 44 | 17 | 0 | 3106.2 | 3,046 | 1,299 | 1,394 | 338 | 684 | 54 | 0 | 26 | 12,760 | 58 | 7.36 | 1.98 | 3.71 | 0.98 | 19.9 | 5.4 | 1.20 | .296 | 4.04 | 8.82 |
| 6 | | J. Vazquez | 2,536 | 450 | 165 | 160 | .508 | 443 | 4.22 | 28 | 8 | 0 | 2840.0 | 2,784 | 1,331 | 1,431 | 373 | 763 | 88 | 5 | 58 | 11,935 | 76 | 8.04 | 2.42 | 3.32 | 1.18 | 21.2 | 6.4 | 1.25 | .295 | 4.53 | 8.82 |
| 7 | | A. Pettitte | 2,448 | 531 | 256 | 153 | .626 | 521 | 3.85 | 26 | 4 | 0 | 3316.0 | 3,448 | 1,418 | 1,572 | 288 | 1,031 | 55 | 3 | 42 | 14,074 | 69 | 6.64 | 2.80 | 2.37 | 0.78 | 17.4 | 7.3 | 1.35 | .308 | 4.27 | 9.36 |
| 8 |  | CC Sabathia | 2,437 | 423 | 208 | 119 | .636 | 423 | 3.63 | 37 | 12 | 0 | 2821.1 | 2,643 | 1,137 | 1,248 | 265 | 844 | 89 | 0 | 39 | 11,739 | 59 | 7.77 | 2.69 | 2.89 | 0.85 | 20.8 | 7.2 | 1.24 | .293 | 3.98 | 8.43 |
| 9 | | A.J. Burnett | 2,370 | 409 | 155 | 150 | .508 | 404 | 4.04 | 24 | 10 | 0 | 2567.1 | 2,345 | 1,152 | 1,264 | 252 | 1,051 | 132 | 1 | 33 | 10,966 | 155 | 8.31 | 3.68 | 2.25 | 0.88 | 21.6 | 9.6 | 1.32 | .292 | 4.43 | 8.22 |
| 10 |  | G. Maddux | 2,299 | 507 | 248 | 143 | .634 | 507 | 3.09 | 63 | 22 | 0 | 3385.2 | 3,211 | 1,164 | 1,297 | 259 | 509 | 88 | 0 | 102 | 13,657 | 39 | 6.11 | 1.35 | 4.52 | 0.69 | 16.8 | 3.7 | 1.10 | .281 | 3.45 | 8.54 |
| 11 |  | J. Smoltz | 2,195 | 553 | 146 | 92 | .613 | 311 | 3.25 | 25 | 10 | 154 | 2325.1 | 2,080 | 840 | 904 | 199 | 582 | 39 | 204 | 60 | 9,481 | 78 | 8.50 | 2.25 | 3.77 | 0.77 | 23.2 | 6.1 | 1.14 | .291 | 3.50 | 8.05 |
| 12 | | R. Halladay | 2,117 | 416 | 203 | 105 | .659 | 390 | 3.38 | 67 | 20 | 1 | 2749.1 | 2,646 | 1,034 | 1,135 | 236 | 592 | 81 | 6 | 28 | 11,287 | 56 | 6.93 | 1.94 | 3.58 | 0.77 | 18.8 | 5.2 | 1.18 | .292 | 3.72 | 8.66 |
| 13 |  | B. Colon | 2,101 | 442 | 204 | 141 | .591 | 436 | 3.95 | 35 | 12 | 0 | 2786.0 | 2,812 | 1,224 | 1,335 | 330 | 832 | 53 | 0 | 39 | 11,773 | 42 | 6.79 | 2.69 | 2.53 | 1.07 | 17.8 | 7.1 | 1.31 | .293 | 4.31 | 9.08 |
| 14 | | K. Millwood | 2,083 | 451 | 169 | 152 | .526 | 443 | 4.11 | 22 | 6 | 0 | 2720.1 | 2,770 | 1,243 | 1,357 | 296 | 843 | 74 | 3 | 46 | 11,616 | 67 | 6.89 | 2.79 | 2.47 | 0.98 | 17.9 | 7.3 | 1.33 | .297 | 4.49 | 9.16 |
| 15 | | R. Dempster | 2,075 | 579 | 132 | 133 | .498 | 351 | 4.35 | 11 | 3 | 87 | 2387.0 | 2,347 | 1,154 | 1,250 | 267 | 1,071 | 91 | 186 | 47 | 10,412 | 80 | 7.82 | 4.04 | 1.94 | 1.01 | 19.9 | 10.3 | 1.43 | .301 | 4.71 | 8.85 |
| 16 | | T. Wakefield | 2,062 | 595 | 188 | 171 | .524 | 435 | 4.42 | 28 | 5 | 22 | 3039.1 | 2,964 | 1,493 | 1,697 | 403 | 1,109 | 179 | 77 | 30 | 13,117 | 129 | 6.11 | 3.28 | 1.86 | 1.19 | 15.7 | 8.5 | 1.34 | .273 | 5.03 | 8.78 |
| 17 | | J. Peavy | 2,027 | 338 | 139 | 111 | .556 | 337 | 3.53 | 15 | 6 | 0 | 2147.2 | 1,901 | 843 | 890 | 229 | 647 | 74 | 0 | 40 | 8,870 | 40 | 8.49 | 2.71 | 3.13 | 0.96 | 22.9 | 7.3 | 1.19 | .284 | 3.73 | 7.97 |
| 18 | | T. Hudson | 2,016 | 458 | 214 | 124 | .633 | 457 | 3.45 | 26 | 13 | 0 | 3003.0 | 2,823 | 1,152 | 1,257 | 235 | 880 | 117 | 0 | 83 | 12,480 | 80 | 6.04 | 2.64 | 2.29 | 0.70 | 16.2 | 7.1 | 1.23 | .280 | 3.77 | 8.46 |
| 19 | | J. Santana | 1,988 | 360 | 139 | 78 | .641 | 284 | 3.20 | 15 | 10 | 1 | 2025.2 | 1,726 | 721 | 773 | 220 | 567 | 36 | 23 | 13 | 8,262 | 68 | 8.83 | 2.52 | 3.51 | 0.98 | 24.1 | 6.9 | 1.13 | .276 | 3.43 | 7.67 |
| 20 | | L. Hernandez | 1,976 | 519 | 178 | 177 | .501 | 474 | 4.44 | 50 | 9 | 1 | 3189.0 | 3,525 | 1,572 | 1,686 | 362 | 1,066 | 78 | 17 | 86 | 13,816 | 41 | 5.58 | 3.01 | 1.85 | 1.02 | 14.3 | 7.7 | 1.44 | .306 | 4.76 | 9.95 |
| 21 | | J. Moyer | 1,962 | 539 | 228 | 150 | .603 | 511 | 4.18 | 25 | 7 | 0 | 3286.2 | 3,369 | 1,528 | 1,637 | 436 | 847 | 125 | 6 | 47 | 13,909 | 35 | 5.37 | 2.32 | 2.32 | 1.19 | 14.1 | 6.1 | 1.28 | .278 | 4.48 | 9.23 |
| 22 |  | F. Hernandez | 1,951 | 303 | 125 | 92 | .576 | 303 | 3.07 | 23 | 9 | 0 | 2060.2 | 1,839 | 704 | 790 | 161 | 572 | 62 | 0 | 16 | 8,425 | 116 | 8.52 | 2.50 | 3.41 | 0.70 | 23.2 | 6.8 | 1.17 | .295 | 3.45 | 8.03 |
| 23 | | H. Nomo | 1,918 | 323 | 123 | 109 | .530 | 318 | 4.24 | 16 | 9 | 0 | 1976.1 | 1,768 | 932 | 993 | 251 | 908 | 38 | 2 | 31 | 8,462 | 110 | 8.73 | 4.13 | 2.11 | 1.14 | 22.7 | 10.7 | 1.35 | .284 | 4.52 | 8.05 |
| 24 | | J. Beckett | 1,901 | 335 | 138 | 106 | .566 | 332 | 3.88 | 12 | 6 | 0 | 2051.0 | 1,897 | 884 | 957 | 238 | 629 | 76 | 1 | 28 | 8,579 | 59 | 8.34 | 2.76 | 3.02 | 1.04 | 22.2 | 7.3 | 1.23 | .289 | 4.20 | 8.32 |
| 25 | | T. Glavine | 1,889 | 485 | 219 | 139 | .612 | 485 | 3.54 | 28 | 13 | 0 | 3127.2 | 3,084 | 1,229 | 1,330 | 269 | 1,075 | 46 | 0 | 102 | 13,205 | 34 | 5.44 | 3.09 | 1.76 | 0.77 | 14.3 | 8.1 | 1.33 | .284 | 3.83 | 8.87 |
StatMuse has game-level data for strikeouts going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
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