Between August 5, 1912 and September 29, 1935, Walter Johnson struck out the most hitters, with 2,395 strikeouts.
| NAME | SO | G | W | L | W% | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | H/9 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | W. Johnson | 2,395 | 595 | 313 | 194 | .617 | 483 | 2.30 | 372 | 78 | 28 | 4314.2 | 3,658 | 1,412 | 84 | 1,018 | 143 | 105 | 79 | 5.00 | 2.12 | 2.35 | 0.18 | 5.9 | 1.08 | .261 | 2.95 | 7.63 | ||||
| 2 |  | D. Vance | 2,045 | 442 | 197 | 140 | .585 | 349 | 3.24 | 217 | 29 | 12 | 2967.2 | 2,808 | 1,068 | 1,247 | 132 | 842 | 77 | 52 | 12,379 | 37 | 6.20 | 2.55 | 2.43 | 0.40 | 16.5 | 6.8 | 1.23 | .288 | 3.78 | 8.52 | |
| 3 | | G. Alexander | 1,839 | 618 | 331 | 187 | .639 | 542 | 2.54 | 391 | 82 | 27 | 4624.0 | 4,399 | 1,627 | 152 | 744 | 57 | 62 | 29 | 3.58 | 1.45 | 2.47 | 0.30 | 4.0 | 1.11 | .268 | 3.17 | 8.56 | ||||
| 4 | | L. Grove | 1,690 | 459 | 223 | 99 | .693 | 309 | 3.01 | 207 | 22 | 51 | 2780.2 | 2,679 | 931 | 1,120 | 95 | 835 | 31 | 116 | 11,685 | 39 | 5.47 | 2.70 | 2.02 | 0.31 | 14.5 | 7.1 | 1.26 | .286 | 3.63 | 8.67 | |
| 5 | | B. Grimes | 1,521 | 616 | 270 | 212 | .560 | 496 | 3.54 | 314 | 35 | 17 | 4177.0 | 4,420 | 2,048 | 149 | 1,297 | 97 | 94 | 17,974 | 92 | 3.28 | 2.79 | 1.17 | 0.32 | 8.5 | 7.2 | 1.37 | .286 | 4.41 | 9.52 | ||
| 6 | | R. Faber | 1,476 | 669 | 254 | 213 | .544 | 483 | 3.15 | 273 | 29 | 27 | 4088.0 | 4,110 | 1,816 | 112 | 1,221 | 106 | 134 | 52 | 3.25 | 2.69 | 1.21 | 0.25 | 7.1 | 1.30 | .278 | 4.00 | 9.05 | ||||
| 7 | | B. Shawkey | 1,367 | 488 | 195 | 150 | .565 | 333 | 3.10 | 197 | 33 | 29 | 2939.1 | 2,722 | 1,012 | 1,202 | 111 | 1,022 | 43 | 115 | 12,183 | 42 | 4.19 | 3.13 | 1.34 | 0.34 | 11.2 | 8.4 | 1.27 | .271 | 3.68 | 8.33 | |
| 8 | | E. Rixey | 1,325 | 683 | 262 | 248 | .514 | 546 | 3.15 | 285 | 35 | 14 | 4429.1 | 4,581 | 1,968 | 92 | 1,061 | 77 | 99 | 94 | 2.69 | 2.16 | 1.25 | 0.19 | 5.7 | 1.27 | .282 | 4.00 | 9.31 | ||||
| 9 | | B. Joe Bush | 1,323 | 488 | 196 | 184 | .516 | 370 | 3.50 | 224 | 35 | 21 | 3083.1 | 3,006 | 1,441 | 96 | 1,268 | 62 | 93 | 87 | 3.86 | 3.70 | 1.04 | 0.28 | 9.6 | 1.39 | .278 | 4.21 | 8.77 | ||||
| 10 | | W. Cooper | 1,257 | 517 | 216 | 178 | .548 | 406 | 2.91 | 279 | 35 | 14 | 3477.1 | 3,415 | 1,406 | 103 | 851 | 100 | 81 | 44 | 3.25 | 2.20 | 1.48 | 0.27 | 5.9 | 1.23 | .274 | 3.64 | 8.84 | ||||
| 11 | | R. Ruffing | 1,244 | 396 | 132 | 158 | .455 | 310 | 4.15 | 182 | 18 | 18 | 2526.2 | 2,552 | 1,164 | 1,350 | 125 | 997 | 43 | 69 | 10,953 | 29 | 4.43 | 3.55 | 1.25 | 0.45 | 11.4 | 9.1 | 1.40 | .284 | 4.81 | 9.09 | |
| 12 | | S. Sam Jones | 1,220 | 647 | 229 | 217 | .513 | 488 | 3.84 | 250 | 36 | 31 | 3880.0 | 4,096 | 2,007 | 154 | 1,408 | 71 | 115 | 73 | 2.83 | 3.27 | 0.87 | 0.36 | 8.4 | 1.42 | .284 | 4.66 | 9.50 | ||||
| 13 | | H. Dauss | 1,208 | 538 | 223 | 182 | .551 | 388 | 3.32 | 244 | 22 | 41 | 3390.1 | 3,408 | 1,594 | 86 | 1,066 | 130 | 120 | 48 | 3.21 | 2.83 | 1.13 | 0.23 | 7.4 | 1.32 | .280 | 4.23 | 9.05 | ||||
| 14 | | H. Pennock | 1,197 | 603 | 239 | 160 | .599 | 417 | 3.57 | 248 | 35 | 36 | 3532.1 | 3,869 | 1,681 | 127 | 903 | 36 | 125 | 63 | 3.05 | 2.30 | 1.33 | 0.32 | 6.0 | 1.35 | .293 | 4.28 | 9.86 | ||||
| 15 | | D. Leonard | 1,162 | 331 | 139 | 114 | .549 | 273 | 2.76 | 151 | 33 | 13 | 2190.1 | 2,021 | 672 | 853 | 55 | 676 | 73 | 48 | 9,095 | 60 | 4.77 | 2.78 | 1.72 | 0.23 | 12.8 | 7.4 | 1.23 | .276 | 3.50 | 8.30 | |
| 16 | | H. Vaughn | 1,148 | 308 | 151 | 106 | .588 | 271 | 2.32 | 177 | 35 | 4 | 2232.1 | 1,996 | 800 | 35 | 628 | 64 | 34 | 41 | 4.63 | 2.53 | 1.83 | 0.14 | 6.8 | 1.18 | .269 | 3.23 | 8.05 | ||||
| 17 | | E. Whitehill | 1,135 | 430 | 183 | 151 | .548 | 389 | 4.13 | 200 | 14 | 8 | 2954.2 | 3,185 | 1,357 | 1,615 | 140 | 1,129 | 80 | 33 | 12,973 | 29 | 3.46 | 3.44 | 1.01 | 0.43 | 8.7 | 8.7 | 1.46 | .290 | 4.92 | 9.70 | |
| 18 | | G. Uhle | 1,133 | 506 | 200 | 165 | .548 | 368 | 3.99 | 232 | 21 | 27 | 3101.1 | 3,391 | 1,623 | 117 | 963 | 116 | 110 | 13,538 | 55 | 3.29 | 2.79 | 1.18 | 0.34 | 8.4 | 7.1 | 1.40 | .292 | 4.71 | 9.84 | ||
| 19 | | D. Luque | 1,128 | 550 | 194 | 179 | .520 | 366 | 3.24 | 206 | 26 | 29 | 3220.2 | 3,236 | 1,412 | 112 | 920 | 27 | 128 | 50 | 3.15 | 2.57 | 1.23 | 0.31 | 6.8 | 1.29 | .277 | 3.95 | 9.04 | ||||
| 20 | | C. Root | 1,124 | 422 | 159 | 123 | .564 | 273 | 3.51 | 152 | 21 | 22 | 2400.0 | 2,397 | 936 | 1,089 | 129 | 702 | 69 | 105 | 10,131 | 19 | 4.22 | 2.63 | 1.60 | 0.48 | 11.1 | 6.9 | 1.29 | .280 | 4.08 | 8.99 | |
| 21 | | J. Quinn | 1,103 | 640 | 206 | 183 | .530 | 374 | 3.29 | 200 | 28 | 53 | 3295.0 | 3,576 | 1,504 | 93 | 712 | 77 | 179 | 48 | 3.01 | 1.94 | 1.55 | 0.25 | 5.5 | 1.30 | .316 | 4.11 | 9.77 | ||||
| 22 | | W. Hoyt | 1,097 | 608 | 222 | 165 | .574 | 396 | 3.62 | 210 | 25 | 50 | 3432.1 | 3,694 | 1,382 | 1,623 | 140 | 946 | 46 | 150 | 14,679 | 37 | 2.88 | 2.48 | 1.16 | 0.37 | 7.5 | 6.4 | 1.35 | .285 | 4.26 | 9.69 | |
| 23 | | L. Meadows | 1,073 | 490 | 188 | 180 | .511 | 405 | 3.39 | 219 | 25 | 7 | 3156.2 | 3,305 | 1,499 | 85 | 959 | 87 | 58 | 60 | 3.06 | 2.73 | 1.12 | 0.24 | 7.2 | 1.35 | .288 | 4.27 | 9.42 | ||||
| 24 | | R. Marquard | 1,072 | 420 | 146 | 148 | .497 | 321 | 3.21 | 146 | 24 | 15 | 2576.2 | 2,606 | 918 | 1,162 | 91 | 587 | 13 | 67 | 10,662 | 56 | 3.74 | 2.05 | 1.83 | 0.32 | 10.1 | 5.5 | 1.24 | .283 | 4.06 | 9.10 | |
| 25 | | H. Ehmke | 1,033 | 427 | 166 | 166 | .500 | 338 | 3.76 | 199 | 20 | 15 | 2820.2 | 2,882 | 1,427 | 103 | 1,050 | 131 | 68 | 29 | 3.30 | 3.35 | 0.98 | 0.33 | 8.8 | 1.39 | .287 | 4.55 | 9.20 | ||||
StatMuse has game-level data for strikeouts going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
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 Braves - y | 94 | 68 | .580 | |
 Phillies - w | 88 | 74 | .543 | 6.0 |
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| NL Central | W | L | PCT | GB |
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82 | 80 | .506 | 21.0 | |
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 Astros - y | 81 | 81 | .500 | |
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