Between June 2, 1904 and October 3, 1936, Walter Johnson struck out the most hitters, with 3,527 strikeouts.
| NAME | SO | G | W | L | W% | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | H/9 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | W. Johnson | 3,527 | 802 | 417 | 279 | .599 | 666 | 1.70 | 531 | 110 | 34 | 5916.2 | 4,917 | 1,902 | 97 | 1,374 | 208 | 128 | 155 | 5.37 | 2.09 | 2.57 | 0.15 | 5.8 | 1.06 | .262 | 2.89 | 7.48 | ||||
| 2 |  | G. Alexander | 2,209 | 696 | 373 | 208 | .642 | 600 | 2.41 | 437 | 90 | 33 | 5182.2 | 4,866 | 1,851 | 165 | 951 | 67 | 80 | 38 | 3.84 | 1.65 | 2.32 | 0.29 | 4.5 | 1.12 | .268 | 3.21 | 8.45 | ||||
| 3 | | D. Vance | 2,045 | 442 | 197 | 140 | .585 | 349 | 3.24 | 217 | 29 | 12 | 2967.2 | 2,808 | 1,068 | 1,247 | 132 | 842 | 77 | 52 | 12,379 | 37 | 6.20 | 2.55 | 2.43 | 0.40 | 16.5 | 6.8 | 1.23 | .288 | 3.78 | 8.52 | |
| 4 | | E. Plank | 1,832 | 499 | 260 | 144 | .644 | 413 | 0.92 | 306 | 63 | 23 | 3492.1 | 2,972 | 1,132 | 28 | 855 | 130 | 72 | 61 | 4.72 | 2.20 | 2.14 | 0.07 | 6.5 | 1.10 | .286 | 2.92 | 7.66 | ||||
| 5 | | L. Grove | 1,820 | 494 | 240 | 111 | .684 | 339 | 3.00 | 229 | 28 | 53 | 3034.0 | 2,916 | 1,010 | 1,210 | 109 | 900 | 35 | 119 | 12,736 | 39 | 5.40 | 2.67 | 2.02 | 0.32 | 14.3 | 7.1 | 1.26 | .284 | 3.59 | 8.65 | |
| 6 | | C. Mathewson | 1,813 | 497 | 303 | 133 | .695 | 425 | 0.88 | 324 | 63 | 24 | 3672.1 | 3,233 | 1,149 | 78 | 521 | 23 | 63 | 48 | 4.44 | 1.28 | 3.48 | 0.19 | 3.6 | 1.02 | .263 | 2.82 | 7.92 | ||||
| 7 | | E. Walsh | 1,735 | 426 | 193 | 125 | .607 | 313 | 0.37 | 248 | 56 | 35 | 2931.2 | 2,325 | 874 | 22 | 617 | 56 | 104 | 80 | 5.33 | 1.89 | 2.81 | 0.07 | 5.9 | 1.00 | .287 | 2.68 | 7.14 | ||||
| 8 | | R. Ames | 1,717 | 531 | 181 | 167 | .520 | 369 | 1.43 | 206 | 26 | 32 | 3176.2 | 2,887 | 1,308 | 41 | 1,035 | 64 | 118 | 13,083 | 158 | 4.86 | 2.93 | 1.66 | 0.12 | 13.1 | 7.9 | 1.23 | .278 | 3.71 | 8.18 | ||
| 9 | | C. Bender | 1,604 | 419 | 194 | 110 | .638 | 297 | 1.13 | 223 | 38 | 34 | 2720.1 | 2,396 | 981 | 33 | 637 | 76 | 112 | 63 | 5.31 | 2.11 | 2.52 | 0.11 | 6.4 | 1.11 | .311 | 3.25 | 7.93 | ||||
| 10 | | R. Marquard | 1,595 | 536 | 201 | 177 | .532 | 408 | 2.66 | 196 | 30 | 19 | 3305.1 | 3,237 | 1,444 | 108 | 861 | 35 | 85 | 13,661 | 81 | 4.34 | 2.34 | 1.85 | 0.29 | 11.7 | 6.3 | 1.24 | .283 | 3.93 | 8.81 | ||
| 11 | | B. Grimes | 1,521 | 616 | 270 | 212 | .560 | 496 | 3.54 | 314 | 35 | 17 | 4177.0 | 4,420 | 2,048 | 149 | 1,297 | 97 | 94 | 17,974 | 92 | 3.28 | 2.79 | 1.17 | 0.32 | 8.5 | 7.2 | 1.37 | .286 | 4.41 | 9.52 | ||
| 12 | | R. Faber | 1,476 | 669 | 254 | 213 | .544 | 483 | 3.15 | 273 | 29 | 27 | 4088.0 | 4,110 | 1,816 | 112 | 1,221 | 106 | 134 | 52 | 3.25 | 2.69 | 1.21 | 0.25 | 7.1 | 1.30 | .278 | 4.00 | 9.05 | ||||
| 13 | | H. Vaughn | 1,416 | 390 | 178 | 137 | .565 | 332 | 1.92 | 214 | 41 | 5 | 2726.0 | 2,463 | 1,038 | 39 | 803 | 88 | 48 | 63 | 4.67 | 2.65 | 1.76 | 0.13 | 7.1 | 1.20 | .272 | 3.43 | 8.13 | ||||
| 14 | | E. Cicotte | 1,386 | 502 | 209 | 148 | .585 | 361 | 1.53 | 248 | 35 | 24 | 3218.2 | 2,893 | 1,163 | 32 | 831 | 52 | 105 | 57 | 3.88 | 2.32 | 1.67 | 0.09 | 6.4 | 1.16 | .268 | 3.25 | 8.09 | ||||
| 15 | | R. Waddell | 1,375 | 251 | 110 | 85 | .564 | 201 | 0.30 | 138 | 36 | 5 | 1690.0 | 1,379 | 578 | 15 | 486 | 60 | 38 | 39 | 7.32 | 2.59 | 2.83 | 0.08 | 8.6 | 1.10 | .364 | 3.08 | 7.34 | ||||
| 16 | | B. Shawkey | 1,367 | 488 | 195 | 150 | .565 | 333 | 3.10 | 197 | 33 | 29 | 2939.1 | 2,722 | 1,012 | 1,202 | 111 | 1,022 | 43 | 115 | 12,183 | 42 | 4.19 | 3.13 | 1.34 | 0.34 | 11.2 | 8.4 | 1.27 | .271 | 3.68 | 8.33 | |
| 17 | | E. Rixey | 1,351 | 692 | 266 | 251 | .515 | 554 | 3.15 | 289 | 37 | 14 | 4493.0 | 4,639 | 1,993 | 93 | 1,084 | 77 | 100 | 97 | 2.71 | 2.17 | 1.25 | 0.19 | 5.8 | 1.27 | .281 | 3.99 | 9.29 | ||||
| 18 | | R. Ruffing | 1,346 | 429 | 152 | 170 | .472 | 343 | 4.12 | 207 | 21 | 18 | 2797.2 | 2,826 | 1,280 | 1,483 | 148 | 1,087 | 46 | 69 | 12,104 | 36 | 4.33 | 3.50 | 1.24 | 0.48 | 11.1 | 9.0 | 1.40 | .283 | 4.77 | 9.09 | |
| 19 | | J. Quinn | 1,342 | 756 | 246 | 217 | .531 | 443 | 2.80 | 242 | 28 | 56 | 3924.1 | 4,243 | 1,835 | 102 | 859 | 95 | 218 | 59 | 3.08 | 1.97 | 1.56 | 0.23 | 5.5 | 1.30 | .313 | 4.21 | 9.73 | ||||
| 20 | | B. Joe Bush | 1,323 | 488 | 196 | 184 | .516 | 370 | 3.50 | 224 | 35 | 21 | 3083.1 | 3,006 | 1,441 | 96 | 1,268 | 62 | 93 | 87 | 3.86 | 3.70 | 1.04 | 0.28 | 9.6 | 1.39 | .278 | 4.21 | 8.77 | ||||
| 21 | | M. Brown | 1,286 | 449 | 227 | 117 | .660 | 303 | 0.87 | 247 | 53 | 38 | 2913.0 | 2,442 | 918 | 35 | 604 | 56 | 136 | 53 | 3.97 | 1.87 | 2.13 | 0.11 | 5.6 | 1.05 | .272 | 2.84 | 7.54 | ||||
| 22 | | W. Cooper | 1,257 | 517 | 216 | 178 | .548 | 406 | 2.91 | 279 | 35 | 14 | 3477.1 | 3,415 | 1,406 | 103 | 851 | 100 | 81 | 44 | 3.25 | 2.20 | 1.48 | 0.27 | 5.9 | 1.23 | .274 | 3.64 | 8.84 | ||||
| 23 | | H. Pennock | 1,229 | 617 | 240 | 162 | .597 | 419 | 3.55 | 249 | 35 | 37 | 3570.2 | 3,902 | 1,699 | 128 | 924 | 38 | 136 | 65 | 3.10 | 2.33 | 1.33 | 0.32 | 6.1 | 1.35 | .293 | 4.28 | 9.84 | ||||
| 24 | | N. Rucker | 1,222 | 336 | 134 | 135 | .498 | 274 | 1.00 | 187 | 38 | 13 | 2358.2 | 2,090 | 822 | 41 | 704 | 75 | 58 | 9,556 | 43 | 4.66 | 2.69 | 1.74 | 0.16 | 12.8 | 7.4 | 1.18 | .273 | 3.14 | 7.97 | ||
| 25 | | S. Sam Jones | 1,220 | 647 | 229 | 217 | .513 | 488 | 3.84 | 250 | 36 | 31 | 3880.0 | 4,096 | 2,007 | 154 | 1,408 | 71 | 115 | 73 | 2.83 | 3.27 | 0.87 | 0.36 | 8.4 | 1.42 | .284 | 4.66 | 9.50 | ||||
StatMuse has game-level data for strikeouts going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
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| NL East | W | L | PCT | GB |
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 Braves - y | 94 | 68 | .580 | |
 Phillies - w | 88 | 74 | .543 | 6.0 |
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| NL Central | W | L | PCT | GB |
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 Astros - y | 81 | 81 | .500 | |
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