Between June 4, 1913 and October 3, 1937, Walter Johnson struck out the most hitters, with 2,226 strikeouts.
| NAME | SO | G | W | L | W% | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | H/9 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | W. Johnson | 2,226 | 562 | 291 | 186 | .610 | 461 | 2.40 | 353 | 73 | 27 | 4088.2 | 3,486 | 1,366 | 82 | 983 | 135 | 94 | 77 | 4.90 | 2.16 | 2.26 | 0.18 | 6.0 | 1.09 | .261 | 3.01 | 7.67 | ||||
| 2 |  | D. Vance | 2,045 | 442 | 197 | 140 | .585 | 349 | 3.24 | 217 | 29 | 12 | 2967.2 | 2,808 | 1,068 | 1,247 | 132 | 842 | 77 | 52 | 12,379 | 37 | 6.20 | 2.55 | 2.43 | 0.40 | 16.5 | 6.8 | 1.23 | .288 | 3.78 | 8.52 | |
| 3 | | L. Grove | 1,973 | 526 | 257 | 120 | .682 | 371 | 3.00 | 250 | 31 | 53 | 3296.0 | 3,185 | 1,098 | 1,311 | 118 | 982 | 36 | 119 | 13,864 | 44 | 5.39 | 2.68 | 2.01 | 0.32 | 14.2 | 7.1 | 1.26 | .285 | 3.58 | 8.70 | |
| 4 | | G. Alexander | 1,753 | 592 | 319 | 178 | .642 | 521 | 2.56 | 375 | 77 | 27 | 4433.1 | 4,231 | 1,568 | 147 | 704 | 53 | 57 | 29 | 3.56 | 1.43 | 2.49 | 0.30 | 3.9 | 1.11 | .268 | 3.18 | 8.59 | ||||
| 5 | | B. Grimes | 1,521 | 616 | 270 | 212 | .560 | 496 | 3.54 | 314 | 35 | 17 | 4177.0 | 4,420 | 2,048 | 149 | 1,297 | 97 | 94 | 17,974 | 92 | 3.28 | 2.79 | 1.17 | 0.32 | 8.5 | 7.2 | 1.37 | .286 | 4.41 | 9.52 | ||
| 6 | | R. Ruffing | 1,477 | 460 | 172 | 177 | .493 | 374 | 4.02 | 229 | 25 | 18 | 3054.0 | 3,068 | 1,365 | 1,584 | 165 | 1,155 | 47 | 69 | 13,163 | 37 | 4.35 | 3.40 | 1.28 | 0.49 | 11.2 | 8.8 | 1.38 | .281 | 4.67 | 9.04 | |
| 7 | | R. Faber | 1,476 | 669 | 254 | 213 | .544 | 483 | 3.15 | 273 | 29 | 27 | 4088.0 | 4,110 | 1,816 | 112 | 1,221 | 106 | 134 | 52 | 3.25 | 2.69 | 1.21 | 0.25 | 7.1 | 1.30 | .278 | 4.00 | 9.05 | ||||
| 8 | | B. Shawkey | 1,367 | 488 | 195 | 150 | .565 | 333 | 3.10 | 197 | 33 | 29 | 2939.1 | 2,722 | 1,012 | 1,202 | 111 | 1,022 | 43 | 115 | 12,183 | 42 | 4.19 | 3.13 | 1.34 | 0.34 | 11.2 | 8.4 | 1.27 | .271 | 3.68 | 8.33 | |
| 9 | | B. Joe Bush | 1,298 | 477 | 193 | 183 | .513 | 368 | 3.51 | 224 | 35 | 21 | 3033.2 | 2,959 | 1,414 | 96 | 1,247 | 58 | 87 | 87 | 3.85 | 3.70 | 1.04 | 0.28 | 9.6 | 1.39 | .278 | 4.19 | 8.78 | ||||
| 10 | | E. Rixey | 1,277 | 664 | 254 | 240 | .514 | 531 | 3.17 | 278 | 34 | 14 | 4305.0 | 4,460 | 1,928 | 90 | 1,024 | 75 | 97 | 88 | 2.67 | 2.14 | 1.25 | 0.19 | 5.7 | 1.27 | .281 | 4.03 | 9.32 | ||||
| 11 | | C. Hubbell | 1,259 | 389 | 192 | 102 | .653 | 312 | 2.79 | 201 | 32 | 29 | 2654.0 | 2,509 | 823 | 968 | 144 | 501 | 44 | 64 | 10,859 | 37 | 4.27 | 1.70 | 2.51 | 0.49 | 11.6 | 4.6 | 1.13 | .265 | 3.28 | 8.51 | |
| 12 | | E. Whitehill | 1,251 | 491 | 205 | 170 | .547 | 439 | 4.29 | 220 | 15 | 10 | 3314.1 | 3,626 | 1,578 | 1,850 | 166 | 1,298 | 88 | 40 | 14,612 | 35 | 3.40 | 3.52 | 0.96 | 0.45 | 8.6 | 8.9 | 1.49 | .293 | 5.02 | 9.85 | |
| 13 | | C. Root | 1,230 | 498 | 175 | 134 | .566 | 291 | 3.52 | 157 | 21 | 28 | 2652.1 | 2,651 | 1,037 | 1,194 | 150 | 754 | 75 | 140 | 11,176 | 21 | 4.17 | 2.56 | 1.63 | 0.51 | 11.0 | 6.7 | 1.28 | .279 | 4.05 | 9.00 | |
| 14 | | S. Sam Jones | 1,220 | 647 | 229 | 217 | .513 | 488 | 3.84 | 250 | 36 | 31 | 3880.0 | 4,096 | 2,007 | 154 | 1,408 | 71 | 115 | 73 | 2.83 | 3.27 | 0.87 | 0.36 | 8.4 | 1.42 | .284 | 4.66 | 9.50 | ||||
| 15 | | W. Cooper | 1,214 | 504 | 212 | 178 | .544 | 399 | 2.92 | 275 | 32 | 14 | 3412.2 | 3,358 | 1,386 | 102 | 817 | 100 | 76 | 42 | 3.20 | 2.15 | 1.49 | 0.27 | 5.8 | 1.22 | .274 | 3.66 | 8.86 | ||||
| 16 | | W. Hoyt | 1,199 | 668 | 237 | 179 | .570 | 424 | 3.58 | 226 | 26 | 53 | 3744.0 | 4,020 | 1,491 | 1,764 | 153 | 1,002 | 49 | 170 | 15,991 | 39 | 2.88 | 2.41 | 1.20 | 0.37 | 7.5 | 6.3 | 1.34 | .285 | 4.24 | 9.66 | |
| 17 | | H. Dauss | 1,190 | 532 | 222 | 179 | .554 | 382 | 3.32 | 241 | 22 | 41 | 3350.1 | 3,375 | 1,567 | 82 | 1,044 | 126 | 120 | 47 | 3.20 | 2.80 | 1.14 | 0.22 | 7.4 | 1.32 | .280 | 4.21 | 9.07 | ||||
| 18 | | H. Pennock | 1,184 | 595 | 238 | 159 | .599 | 416 | 3.57 | 248 | 35 | 35 | 3511.0 | 3,845 | 1,660 | 125 | 888 | 35 | 122 | 63 | 3.04 | 2.28 | 1.33 | 0.32 | 6.0 | 1.35 | .293 | 4.26 | 9.86 | ||||
| 19 | | G. Uhle | 1,138 | 513 | 200 | 166 | .546 | 368 | 4.01 | 232 | 21 | 27 | 3114.0 | 3,417 | 1,635 | 119 | 968 | 116 | 115 | 13,606 | 55 | 3.29 | 2.80 | 1.18 | 0.34 | 8.4 | 7.1 | 1.41 | .293 | 4.73 | 9.88 | ||
| 20 | | H. Vaughn | 1,138 | 305 | 151 | 105 | .590 | 270 | 2.34 | 177 | 35 | 4 | 2214.0 | 1,970 | 789 | 35 | 622 | 64 | 32 | 41 | 4.63 | 2.53 | 1.83 | 0.14 | 6.8 | 1.17 | .267 | 3.21 | 8.01 | ||||
| 21 | | D. Leonard | 1,129 | 321 | 136 | 111 | .551 | 267 | 2.76 | 150 | 33 | 13 | 2126.1 | 1,970 | 653 | 829 | 55 | 644 | 71 | 45 | 8,817 | 59 | 4.78 | 2.73 | 1.75 | 0.23 | 12.8 | 7.3 | 1.23 | .277 | 3.51 | 8.34 | |
| 22 | | D. Luque | 1,128 | 550 | 194 | 179 | .520 | 366 | 3.24 | 206 | 26 | 29 | 3220.2 | 3,236 | 1,412 | 112 | 920 | 27 | 128 | 50 | 3.15 | 2.57 | 1.23 | 0.31 | 6.8 | 1.29 | .277 | 3.95 | 9.04 | ||||
| 23 | | B. Hadley | 1,116 | 420 | 132 | 140 | .485 | 307 | 4.28 | 118 | 12 | 17 | 2428.1 | 2,443 | 1,154 | 1,328 | 126 | 1,187 | 54 | 75 | 10,708 | 49 | 4.14 | 4.40 | 0.94 | 0.47 | 10.4 | 11.1 | 1.49 | .282 | 4.92 | 9.05 | |
| 24 | | L. Gomez | 1,106 | 264 | 135 | 69 | .662 | 220 | 3.20 | 129 | 20 | 10 | 1796.2 | 1,618 | 639 | 758 | 105 | 721 | 13 | 28 | 7,621 | 22 | 5.54 | 3.61 | 1.53 | 0.53 | 14.5 | 9.5 | 1.30 | .267 | 3.80 | 8.11 | |
| 25 | | J. Quinn | 1,103 | 640 | 206 | 183 | .530 | 374 | 3.29 | 200 | 28 | 53 | 3295.0 | 3,576 | 1,504 | 93 | 712 | 77 | 179 | 48 | 3.01 | 1.94 | 1.55 | 0.25 | 5.5 | 1.30 | .316 | 4.11 | 9.77 | ||||
StatMuse has game-level data for strikeouts going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
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 Braves - y | 94 | 68 | .580 | |
 Phillies - w | 88 | 74 | .543 | 6.0 |
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| NL Central | W | L | PCT | GB |
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82 | 80 | .506 | 21.0 | |
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 Astros - y | 81 | 81 | .500 | |
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