Between September 11, 1973 and October 1, 1995, Nolan Ryan struck out the most hitters, with 4,566 strikeouts.
| NAME | SO | G | W | L | W% | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | H/9 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | N. Ryan | 4,566 | 627 | 260 | 222 | .539 | 626 | 3.22 | 168 | 46 | 0 | 4313.0 | 3,185 | 1,545 | 1,770 | 256 | 2,158 | 117 | 1 | 58 | 18,037 | 225 | 9.53 | 4.50 | 2.12 | 0.53 | 25.3 | 12.0 | 1.24 | .268 | 3.69 | 6.65 |
| 2 |  | B. Blyleven | 2,893 | 553 | 227 | 194 | .539 | 549 | 3.45 | 189 | 43 | 0 | 3958.1 | 3,706 | 1,517 | 1,677 | 356 | 1,086 | 130 | 1 | 53 | 16,373 | 93 | 6.58 | 2.47 | 2.66 | 0.81 | 17.7 | 6.6 | 1.21 | .281 | 3.81 | 8.43 |
| 3 | | F. Tanana | 2,770 | 637 | 240 | 235 | .505 | 615 | 3.65 | 143 | 34 | 1 | 4184.1 | 4,058 | 1,698 | 1,906 | 447 | 1,251 | 129 | 10 | 116 | 17,620 | 119 | 5.96 | 2.69 | 2.21 | 0.96 | 15.7 | 7.1 | 1.27 | .277 | 4.10 | 8.73 |
| 4 |  | S. Carlton | 2,669 | 474 | 214 | 154 | .582 | 460 | 3.32 | 143 | 28 | 1 | 3344.2 | 2,984 | 1,235 | 1,415 | 279 | 1,193 | 32 | 6 | 91 | 13,896 | 118 | 7.18 | 3.21 | 2.24 | 0.75 | 19.2 | 8.6 | 1.25 | .278 | 3.81 | 8.03 |
| 5 |  | J. Morris | 2,478 | 549 | 254 | 186 | .577 | 527 | 3.90 | 175 | 28 | 0 | 3824.0 | 3,567 | 1,657 | 1,815 | 389 | 1,390 | 58 | 10 | 99 | 16,120 | 205 | 5.83 | 3.27 | 1.78 | 0.92 | 15.4 | 8.6 | 1.30 | .269 | 4.27 | 8.40 |
| 6 |  | R. Clemens | 2,333 | 349 | 182 | 98 | .650 | 348 | 3.00 | 94 | 36 | 0 | 2533.1 | 2,143 | 845 | 939 | 175 | 750 | 82 | 0 | 41 | 10,352 | 64 | 8.29 | 2.66 | 3.11 | 0.62 | 22.5 | 7.2 | 1.14 | .281 | 3.34 | 7.61 |
| 7 | | C. Hough | 2,293 | 815 | 214 | 214 | .500 | 440 | 3.75 | 107 | 13 | 57 | 3723.2 | 3,228 | 1,552 | 1,773 | 373 | 1,614 | 167 | 218 | 42 | 15,827 | 177 | 5.54 | 3.90 | 1.42 | 0.90 | 14.5 | 10.2 | 1.30 | .251 | 4.29 | 7.80 |
| 8 | | D. Eckersley | 2,285 | 901 | 192 | 159 | .547 | 361 | 3.48 | 100 | 20 | 323 | 3133.0 | 2,916 | 1,213 | 1,311 | 324 | 716 | 67 | 464 | 85 | 12,894 | 26 | 6.56 | 2.06 | 3.19 | 0.93 | 17.7 | 5.6 | 1.16 | .273 | 3.77 | 8.38 |
| 9 | | M. Langston | 2,250 | 382 | 166 | 140 | .542 | 379 | 3.80 | 79 | 18 | 0 | 2642.0 | 2,362 | 1,116 | 1,236 | 265 | 1,142 | 42 | 1 | 26 | 11,135 | 79 | 7.66 | 3.89 | 1.97 | 0.90 | 20.2 | 10.3 | 1.33 | .282 | 4.21 | 8.05 |
| 10 | | P. Niekro | 2,178 | 509 | 208 | 182 | .533 | 495 | 3.54 | 145 | 26 | 3 | 3511.2 | 3,358 | 1,381 | 1,578 | 317 | 1,321 | 81 | 10 | 50 | 14,903 | 128 | 5.58 | 3.39 | 1.65 | 0.81 | 14.6 | 8.9 | 1.33 | .276 | 4.04 | 8.61 |
| 11 | | D. Sutton | 2,035 | 486 | 206 | 153 | .574 | 482 | 3.42 | 91 | 27 | 2 | 3293.0 | 2,987 | 1,250 | 1,374 | 326 | 840 | 45 | 3 | 50 | 13,546 | 59 | 5.56 | 2.30 | 2.42 | 0.89 | 15.0 | 6.2 | 1.16 | .258 | 3.76 | 8.16 |
| 12 | | D. Martinez | 2,022 | 610 | 231 | 176 | .568 | 528 | 3.60 | 120 | 28 | 6 | 3747.2 | 3,601 | 1,500 | 1,673 | 344 | 1,080 | 110 | 40 | 62 | 15,636 | 82 | 4.86 | 2.59 | 1.87 | 0.83 | 12.9 | 6.9 | 1.25 | .270 | 4.02 | 8.65 |
| 13 |  | T. Seaver | 2,011 | 410 | 179 | 130 | .579 | 406 | 3.21 | 111 | 37 | 0 | 2882.2 | 2,483 | 1,027 | 1,129 | 240 | 907 | 39 | 1 | 82 | 11,819 | 84 | 6.28 | 2.83 | 2.22 | 0.75 | 17.0 | 7.7 | 1.18 | .260 | 3.52 | 7.75 |
| 14 | | B. Welch | 1,969 | 506 | 211 | 146 | .591 | 462 | 3.47 | 61 | 28 | 8 | 3092.0 | 2,894 | 1,191 | 1,310 | 267 | 1,034 | 79 | 20 | 60 | 12,956 | 55 | 5.73 | 3.01 | 1.90 | 0.78 | 15.2 | 8.0 | 1.27 | .273 | 3.81 | 8.42 |
| 15 | | F. Valenzuela | 1,918 | 402 | 158 | 133 | .543 | 375 | 3.49 | 112 | 31 | 2 | 2669.1 | 2,435 | 1,036 | 1,164 | 197 | 1,038 | 20 | 10 | 63 | 11,238 | 108 | 6.47 | 3.50 | 1.85 | 0.66 | 17.1 | 9.2 | 1.30 | .277 | 3.92 | 8.21 |
| 16 | | D. Gooden | 1,875 | 305 | 157 | 85 | .649 | 303 | 3.10 | 67 | 23 | 1 | 2169.2 | 1,898 | 747 | 823 | 123 | 651 | 41 | 1 | 31 | 8,898 | 47 | 7.78 | 2.70 | 2.88 | 0.51 | 21.1 | 7.3 | 1.17 | .286 | 3.41 | 7.87 |
| 17 | | F. Viola | 1,826 | 415 | 175 | 147 | .543 | 414 | 3.69 | 74 | 16 | 0 | 2806.0 | 2,784 | 1,149 | 1,275 | 288 | 843 | 46 | 0 | 36 | 11,783 | 85 | 5.86 | 2.70 | 2.17 | 0.92 | 15.5 | 7.2 | 1.29 | .284 | 4.09 | 8.93 |
| 18 | | R. Guidry | 1,778 | 368 | 170 | 91 | .651 | 323 | 3.29 | 95 | 26 | 4 | 2392.0 | 2,198 | 874 | 953 | 226 | 633 | 13 | 23 | 24 | 9,794 | 56 | 6.69 | 2.38 | 2.81 | 0.85 | 18.2 | 6.5 | 1.18 | .276 | 3.59 | 8.27 |
| 19 | | R. Reuschel | 1,765 | 504 | 192 | 168 | .533 | 479 | 3.42 | 91 | 20 | 5 | 3203.1 | 3,246 | 1,217 | 1,362 | 203 | 852 | 81 | 15 | 106 | 13,453 | 78 | 4.96 | 2.39 | 2.07 | 0.57 | 13.1 | 6.3 | 1.28 | .288 | 3.83 | 9.12 |
| 20 | | D. Cone | 1,741 | 288 | 129 | 78 | .623 | 259 | 3.18 | 50 | 21 | 1 | 1922.0 | 1,589 | 679 | 746 | 151 | 716 | 55 | 9 | 29 | 7,959 | 98 | 8.15 | 3.35 | 2.43 | 0.71 | 21.9 | 9.0 | 1.20 | .272 | 3.49 | 7.44 |
| 21 | | D. Stewart | 1,741 | 523 | 168 | 129 | .566 | 348 | 3.95 | 55 | 9 | 19 | 2629.2 | 2,499 | 1,154 | 1,259 | 264 | 1,034 | 62 | 87 | 46 | 11,251 | 119 | 5.96 | 3.54 | 1.68 | 0.90 | 15.5 | 9.2 | 1.34 | .274 | 4.31 | 8.55 |
| 22 | | F. Bannister | 1,723 | 431 | 134 | 143 | .484 | 363 | 4.06 | 62 | 16 | 0 | 2388.0 | 2,320 | 1,078 | 1,189 | 291 | 846 | 40 | 13 | 39 | 10,187 | 84 | 6.49 | 3.19 | 2.04 | 1.10 | 16.9 | 8.3 | 1.33 | .278 | 4.48 | 8.74 |
| 23 | | J. Koosman | 1,698 | 416 | 145 | 142 | .505 | 351 | 3.60 | 83 | 15 | 16 | 2544.1 | 2,497 | 1,018 | 1,140 | 197 | 807 | 46 | 37 | 68 | 10,687 | 49 | 6.01 | 2.85 | 2.10 | 0.70 | 15.9 | 7.6 | 1.30 | .290 | 4.03 | 8.83 |
| 24 | | B. Hurst | 1,689 | 379 | 145 | 113 | .562 | 359 | 3.92 | 83 | 23 | 0 | 2417.1 | 2,463 | 1,052 | 1,143 | 258 | 740 | 28 | 5 | 42 | 10,204 | 56 | 6.29 | 2.76 | 2.28 | 0.96 | 16.6 | 7.3 | 1.33 | .294 | 4.26 | 9.17 |
| 25 | | R. Sutcliffe | 1,679 | 457 | 171 | 139 | .552 | 392 | 4.08 | 72 | 18 | 6 | 2697.2 | 2,662 | 1,223 | 1,324 | 236 | 1,081 | 46 | 30 | 75 | 11,548 | 100 | 5.60 | 3.61 | 1.55 | 0.79 | 14.5 | 9.4 | 1.39 | .285 | 4.42 | 8.88 |
StatMuse has game-level data for strikeouts going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
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| NL East | W | L | PCT | GB |
|---|---|---|---|---|
 Braves - y | 94 | 68 | .580 | |
 Phillies - w | 88 | 74 | .543 | 6.0 |
80 | 82 | .494 | 14.0 | |
77 | 85 | .475 | 17.0 | |
74 | 88 | .457 | 20.0 | |
| NL Central | W | L | PCT | GB |
 Brewers - y | 103 | 59 | .636 | |
 Cubs - w | 89 | 73 | .549 | 14.0 |
82 | 80 | .506 | 21.0 | |
77 | 85 | .475 | 26.0 | |
75 | 87 | .463 | 28.0 | |
| NL West | W | L | PCT | GB |
 Dodgers - y | 100 | 62 | .617 | |
 Padres - w | 91 | 71 | .562 | 9.0 |
86 | 76 | .531 | 14.0 | |
65 | 97 | .401 | 35.0 | |
58 | 104 | .358 | 42.0 |
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Reds
Diamondbacks
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Rockies| AL East | W | L | PCT | GB |
|---|---|---|---|---|
 Rays - y | 98 | 64 | .605 | |
 Yankees - w | 93 | 68 | .578 | 4.5 |
 Red Sox - w | 87 | 75 | .537 | 11.0 |
79 | 82 | .491 | 18.5 | |
79 | 83 | .488 | 19.0 | |
| AL Central | W | L | PCT | GB |
 Guardians - y | 85 | 77 | .525 | |
 White Sox - w | 84 | 78 | .519 | 1.0 |
77 | 85 | .475 | 8.0 | |
76 | 86 | .469 | 9.0 | |
69 | 93 | .426 | 16.0 | |
| AL West | W | L | PCT | GB |
 Astros - y | 81 | 81 | .500 | |
80 | 82 | .494 | 1.0 | |
76 | 86 | .469 | 5.0 | |
64 | 98 | .395 | 17.0 | |
62 | 100 | .383 | 19.0 |
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Blue Jays
Twins
Tigers
Royals