Between August 26, 1989 and May 12, 2017, Randy Johnson fanned the most batters, with 4,751 strikeouts.
- Regular season
| NAME | SO | G | W | L | W% | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | H/9 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | R. Johnson | 4,751 | 591 | 295 | 157 | .653 | 577 | 3.25 | 97 | 37 | 2 | 3983.1 | 3,208 | 1,440 | 1,618 | 399 | 1,406 | 188 | 6 | 35 | 16,390 | 100 | 10.73 | 3.18 | 3.38 | 0.90 | 29.0 | 8.6 | 1.16 | .291 | 3.66 | 7.25 |
| 2 |  | R. Clemens | 3,520 | 542 | 264 | 141 | .652 | 541 | 3.13 | 62 | 25 | 0 | 3695.0 | 3,155 | 1,286 | 1,431 | 272 | 1,226 | 129 | 0 | 47 | 15,255 | 115 | 8.57 | 2.99 | 2.87 | 0.66 | 23.1 | 8.0 | 1.19 | .285 | 3.49 | 7.68 |
| 3 |  | P. Martinez | 3,154 | 476 | 219 | 100 | .687 | 409 | 2.93 | 46 | 17 | 3 | 2827.1 | 2,221 | 919 | 1,006 | 239 | 760 | 141 | 23 | 30 | 11,394 | 62 | 10.04 | 2.42 | 4.15 | 0.76 | 27.7 | 6.7 | 1.05 | .279 | 3.20 | 7.07 |
| 4 |  | C. Schilling | 3,112 | 565 | 216 | 143 | .602 | 432 | 3.43 | 83 | 20 | 22 | 3246.1 | 2,976 | 1,237 | 1,299 | 344 | 701 | 51 | 81 | 42 | 13,208 | 70 | 8.63 | 1.94 | 4.44 | 0.95 | 23.6 | 5.3 | 1.13 | .292 | 3.60 | 8.25 |
| 5 |  | G. Maddux | 3,004 | 646 | 315 | 191 | .623 | 646 | 3.06 | 93 | 30 | 0 | 4383.2 | 4,101 | 1,490 | 1,684 | 310 | 758 | 118 | 0 | 134 | 17,729 | 56 | 6.17 | 1.56 | 3.96 | 0.64 | 16.9 | 4.3 | 1.11 | .280 | 3.46 | 8.42 |
| 6 |  | J. Smoltz | 2,890 | 684 | 199 | 137 | .592 | 442 | 3.31 | 48 | 16 | 154 | 3213.0 | 2,849 | 1,182 | 1,281 | 265 | 912 | 54 | 204 | 80 | 13,181 | 135 | 8.10 | 2.55 | 3.17 | 0.74 | 21.9 | 6.9 | 1.17 | .285 | 3.59 | 7.98 |
| 7 | | M. Mussina | 2,813 | 537 | 270 | 153 | .638 | 536 | 3.68 | 57 | 23 | 0 | 3562.2 | 3,460 | 1,458 | 1,559 | 376 | 785 | 60 | 0 | 29 | 14,593 | 71 | 7.11 | 1.98 | 3.58 | 0.95 | 19.3 | 5.4 | 1.19 | .292 | 3.94 | 8.74 |
| 8 |  | CC Sabathia | 2,753 | 489 | 225 | 143 | .611 | 489 | 3.73 | 38 | 12 | 0 | 3207.1 | 3,045 | 1,328 | 1,449 | 321 | 976 | 107 | 0 | 43 | 13,409 | 67 | 7.73 | 2.74 | 2.82 | 0.90 | 20.5 | 7.3 | 1.25 | .294 | 4.07 | 8.54 |
| 9 | | J. Vazquez | 2,536 | 450 | 165 | 160 | .508 | 443 | 4.22 | 28 | 8 | 0 | 2840.0 | 2,784 | 1,331 | 1,431 | 373 | 763 | 88 | 5 | 58 | 11,935 | 76 | 8.04 | 2.42 | 3.32 | 1.18 | 21.2 | 6.4 | 1.25 | .295 | 4.53 | 8.82 |
| 10 | | A.J. Burnett | 2,513 | 435 | 164 | 157 | .511 | 430 | 3.99 | 24 | 10 | 0 | 2731.1 | 2,519 | 1,210 | 1,328 | 263 | 1,100 | 143 | 1 | 35 | 11,665 | 161 | 8.28 | 3.62 | 2.28 | 0.87 | 21.5 | 9.4 | 1.32 | .295 | 4.38 | 8.30 |
| 11 | | A. Pettitte | 2,448 | 531 | 256 | 153 | .626 | 521 | 3.85 | 26 | 4 | 0 | 3316.0 | 3,448 | 1,418 | 1,572 | 288 | 1,031 | 55 | 3 | 42 | 14,074 | 69 | 6.64 | 2.80 | 2.37 | 0.78 | 17.4 | 7.3 | 1.35 | .308 | 4.27 | 9.36 |
| 12 | | T. Glavine | 2,422 | 614 | 284 | 175 | .619 | 614 | 3.46 | 49 | 21 | 0 | 4006.2 | 3,894 | 1,541 | 1,682 | 320 | 1,373 | 53 | 0 | 132 | 16,863 | 60 | 5.44 | 3.08 | 1.76 | 0.72 | 14.4 | 8.1 | 1.31 | .282 | 3.78 | 8.75 |
| 13 |  | B. Colon | 2,391 | 516 | 234 | 166 | .585 | 507 | 3.97 | 36 | 13 | 0 | 3211.0 | 3,275 | 1,418 | 1,541 | 387 | 897 | 61 | 1 | 46 | 13,545 | 42 | 6.70 | 2.51 | 2.67 | 1.08 | 17.7 | 6.6 | 1.30 | .294 | 4.32 | 9.18 |
| 14 |  | F. Hernandez | 2,286 | 364 | 156 | 111 | .584 | 364 | 3.18 | 25 | 11 | 0 | 2442.1 | 2,196 | 862 | 960 | 209 | 698 | 83 | 0 | 16 | 10,024 | 135 | 8.42 | 2.57 | 3.28 | 0.77 | 22.8 | 7.0 | 1.18 | .294 | 3.54 | 8.09 |
| 15 | | K. Brown | 2,286 | 456 | 198 | 135 | .595 | 446 | 3.28 | 64 | 17 | 0 | 3047.1 | 2,887 | 1,109 | 1,268 | 196 | 830 | 136 | 1 | 40 | 12,667 | 100 | 6.75 | 2.45 | 2.75 | 0.58 | 18.0 | 6.6 | 1.22 | .292 | 3.74 | 8.53 |
| 16 | | C. Finley | 2,257 | 408 | 172 | 142 | .548 | 408 | 3.89 | 52 | 14 | 0 | 2689.1 | 2,584 | 1,162 | 1,295 | 269 | 1,122 | 65 | 0 | 25 | 11,477 | 117 | 7.55 | 3.75 | 2.01 | 0.90 | 19.7 | 9.8 | 1.38 | .298 | 4.33 | 8.65 |
| 17 |  | J. Verlander | 2,239 | 359 | 176 | 108 | .620 | 359 | 3.48 | 23 | 7 | 0 | 2381.1 | 2,111 | 922 | 1,003 | 220 | 719 | 80 | 0 | 23 | 9,847 | 75 | 8.46 | 2.72 | 3.11 | 0.83 | 22.7 | 7.3 | 1.19 | .287 | 3.79 | 7.98 |
| 18 | | D. Cone | 2,221 | 356 | 158 | 111 | .587 | 352 | 3.54 | 42 | 17 | 0 | 2373.1 | 2,065 | 934 | 1,020 | 218 | 939 | 93 | 1 | 29 | 10,008 | 124 | 8.42 | 3.56 | 2.37 | 0.83 | 22.2 | 9.4 | 1.27 | .283 | 3.87 | 7.83 |
| 19 | | J. Peavy | 2,207 | 388 | 152 | 126 | .547 | 377 | 3.63 | 15 | 6 | 0 | 2377.0 | 2,134 | 960 | 1,011 | 259 | 708 | 78 | 3 | 42 | 9,838 | 46 | 8.36 | 2.68 | 3.12 | 0.98 | 22.4 | 7.2 | 1.20 | .285 | 3.83 | 8.08 |
| 20 | | J. Lackey | 2,191 | 424 | 179 | 138 | .565 | 423 | 3.88 | 18 | 8 | 0 | 2711.2 | 2,741 | 1,170 | 1,277 | 291 | 773 | 122 | 0 | 29 | 11,481 | 115 | 7.27 | 2.57 | 2.83 | 0.97 | 19.1 | 6.7 | 1.30 | .302 | 4.24 | 9.10 |
| 21 | | T. Wakefield | 2,156 | 627 | 200 | 180 | .526 | 463 | 4.41 | 33 | 6 | 22 | 3226.1 | 3,152 | 1,582 | 1,791 | 418 | 1,205 | 186 | 78 | 33 | 13,939 | 134 | 6.01 | 3.36 | 1.79 | 1.17 | 15.5 | 8.6 | 1.35 | .274 | 5.00 | 8.79 |
| 22 | | C. Hamels | 2,137 | 344 | 138 | 96 | .590 | 343 | 3.31 | 15 | 7 | 0 | 2247.0 | 2,004 | 826 | 882 | 250 | 604 | 67 | 0 | 41 | 9,195 | 44 | 8.56 | 2.42 | 3.54 | 1.00 | 23.2 | 6.6 | 1.16 | .286 | 3.53 | 8.03 |
| 23 | | R. Halladay | 2,117 | 416 | 203 | 105 | .659 | 390 | 3.38 | 67 | 20 | 1 | 2749.1 | 2,646 | 1,034 | 1,135 | 236 | 592 | 81 | 6 | 28 | 11,287 | 56 | 6.93 | 1.94 | 3.58 | 0.77 | 18.8 | 5.2 | 1.18 | .292 | 3.72 | 8.66 |
| 24 | | J. Moyer | 2,091 | 601 | 238 | 170 | .583 | 549 | 4.23 | 28 | 8 | 0 | 3530.1 | 3,649 | 1,659 | 1,784 | 459 | 935 | 132 | 13 | 52 | 14,973 | 38 | 5.33 | 2.38 | 2.24 | 1.17 | 14.0 | 6.2 | 1.30 | .281 | 4.55 | 9.30 |
| 25 | | K. Millwood | 2,083 | 451 | 169 | 152 | .526 | 443 | 4.11 | 22 | 6 | 0 | 2720.1 | 2,770 | 1,243 | 1,357 | 296 | 843 | 74 | 3 | 46 | 11,616 | 67 | 6.89 | 2.79 | 2.47 | 0.98 | 17.9 | 7.3 | 1.33 | .297 | 4.49 | 9.16 |
StatMuse has game-level data for strikeouts going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
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