Between August 7, 1987 and July 23, 2016, Randy Johnson fanned the most hitters, with 4,875 strikeouts.
| NAME | SO | G | W | L | W% | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | H/9 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | R. Johnson | 4,875 | 618 | 303 | 166 | .646 | 603 | 3.29 | 100 | 37 | 2 | 4135.1 | 3,346 | 1,513 | 1,703 | 411 | 1,497 | 190 | 7 | 37 | 17,067 | 109 | 10.61 | 3.26 | 3.26 | 0.89 | 28.6 | 8.8 | 1.17 | .291 | 3.71 | 7.28 |
| 2 |  | R. Clemens | 4,084 | 616 | 303 | 164 | .649 | 615 | 3.12 | 88 | 38 | 0 | 4244.0 | 3,610 | 1,469 | 1,630 | 311 | 1,385 | 142 | 0 | 56 | 17,485 | 123 | 8.66 | 2.94 | 2.95 | 0.66 | 23.4 | 7.9 | 1.18 | .285 | 3.46 | 7.66 |
| 3 |  | G. Maddux | 3,271 | 715 | 347 | 213 | .620 | 713 | 3.09 | 107 | 34 | 0 | 4849.0 | 4,542 | 1,667 | 1,882 | 335 | 933 | 132 | 2 | 166 | 19,716 | 64 | 6.07 | 1.73 | 3.51 | 0.62 | 16.6 | 4.7 | 1.13 | .280 | 3.49 | 8.43 |
| 4 |  | P. Martinez | 3,154 | 476 | 219 | 100 | .687 | 409 | 2.93 | 46 | 17 | 3 | 2827.1 | 2,221 | 919 | 1,006 | 239 | 760 | 141 | 23 | 30 | 11,394 | 62 | 10.04 | 2.42 | 4.15 | 0.76 | 27.7 | 6.7 | 1.05 | .279 | 3.20 | 7.07 |
| 5 |  | C. Schilling | 3,116 | 569 | 216 | 146 | .597 | 436 | 3.46 | 83 | 20 | 22 | 3261.0 | 2,998 | 1,253 | 1,318 | 347 | 711 | 52 | 81 | 43 | 13,284 | 72 | 8.60 | 1.96 | 4.38 | 0.96 | 23.5 | 5.4 | 1.14 | .293 | 3.64 | 8.27 |
| 6 |  | J. Smoltz | 3,084 | 723 | 213 | 155 | .579 | 481 | 3.33 | 53 | 16 | 154 | 3473.0 | 3,074 | 1,284 | 1,391 | 288 | 1,010 | 57 | 204 | 84 | 14,271 | 145 | 7.99 | 2.62 | 3.05 | 0.75 | 21.6 | 7.1 | 1.18 | .283 | 3.60 | 7.97 |
| 7 | | M. Mussina | 2,813 | 537 | 270 | 153 | .638 | 536 | 3.68 | 57 | 23 | 0 | 3562.2 | 3,460 | 1,458 | 1,559 | 376 | 785 | 60 | 0 | 29 | 14,593 | 71 | 7.11 | 1.98 | 3.58 | 0.95 | 19.3 | 5.4 | 1.19 | .292 | 3.94 | 8.74 |
| 8 |  | CC Sabathia | 2,650 | 469 | 219 | 137 | .615 | 469 | 3.70 | 38 | 12 | 0 | 3089.0 | 2,931 | 1,270 | 1,389 | 300 | 932 | 102 | 0 | 42 | 12,906 | 65 | 7.72 | 2.72 | 2.84 | 0.87 | 20.5 | 7.2 | 1.25 | .295 | 4.05 | 8.54 |
| 9 | | D. Cone | 2,617 | 429 | 192 | 124 | .608 | 413 | 3.43 | 55 | 22 | 1 | 2829.0 | 2,428 | 1,078 | 1,180 | 250 | 1,097 | 105 | 3 | 40 | 11,868 | 144 | 8.33 | 3.49 | 2.39 | 0.80 | 22.1 | 9.2 | 1.25 | .279 | 3.75 | 7.72 |
| 10 | | T. Glavine | 2,607 | 682 | 305 | 203 | .600 | 682 | 3.54 | 56 | 25 | 0 | 4413.1 | 4,298 | 1,734 | 1,900 | 356 | 1,500 | 66 | 0 | 145 | 18,604 | 65 | 5.32 | 3.06 | 1.74 | 0.73 | 14.0 | 8.1 | 1.31 | .280 | 3.87 | 8.76 |
| 11 | | J. Vazquez | 2,536 | 450 | 165 | 160 | .508 | 443 | 4.22 | 28 | 8 | 0 | 2840.0 | 2,784 | 1,331 | 1,431 | 373 | 763 | 88 | 5 | 58 | 11,935 | 76 | 8.04 | 2.42 | 3.32 | 1.18 | 21.2 | 6.4 | 1.25 | .295 | 4.53 | 8.82 |
| 12 | | C. Finley | 2,521 | 473 | 195 | 168 | .537 | 467 | 3.83 | 63 | 15 | 0 | 3090.0 | 2,955 | 1,315 | 1,461 | 298 | 1,279 | 75 | 3 | 33 | 13,165 | 124 | 7.34 | 3.73 | 1.97 | 0.87 | 19.1 | 9.7 | 1.37 | .295 | 4.26 | 8.61 |
| 13 | | A.J. Burnett | 2,513 | 435 | 164 | 157 | .511 | 430 | 3.99 | 24 | 10 | 0 | 2731.1 | 2,519 | 1,210 | 1,328 | 263 | 1,100 | 143 | 1 | 35 | 11,665 | 161 | 8.28 | 3.62 | 2.28 | 0.87 | 21.5 | 9.4 | 1.32 | .295 | 4.38 | 8.30 |
| 14 | | A. Pettitte | 2,448 | 531 | 256 | 153 | .626 | 521 | 3.85 | 26 | 4 | 0 | 3316.0 | 3,448 | 1,418 | 1,572 | 288 | 1,031 | 55 | 3 | 42 | 14,074 | 69 | 6.64 | 2.80 | 2.37 | 0.78 | 17.4 | 7.3 | 1.35 | .308 | 4.27 | 9.36 |
| 15 | | K. Brown | 2,393 | 485 | 210 | 144 | .593 | 475 | 3.27 | 72 | 17 | 0 | 3251.1 | 3,073 | 1,183 | 1,355 | 208 | 901 | 139 | 1 | 42 | 13,523 | 108 | 6.62 | 2.49 | 2.66 | 0.58 | 17.7 | 6.7 | 1.22 | .290 | 3.75 | 8.51 |
| 16 |  | B. Colon | 2,307 | 495 | 226 | 159 | .587 | 486 | 3.95 | 36 | 13 | 0 | 3089.1 | 3,144 | 1,356 | 1,475 | 370 | 877 | 59 | 1 | 44 | 13,041 | 42 | 6.72 | 2.55 | 2.63 | 1.08 | 17.7 | 6.7 | 1.30 | .294 | 4.30 | 9.16 |
| 17 | | J. Moyer | 2,291 | 656 | 253 | 197 | .562 | 600 | 4.22 | 31 | 9 | 0 | 3846.0 | 3,990 | 1,805 | 1,944 | 499 | 1,041 | 139 | 14 | 62 | 16,339 | 45 | 5.36 | 2.44 | 2.20 | 1.17 | 14.0 | 6.4 | 1.31 | .282 | 4.55 | 9.34 |
| 18 |  | F. Hernandez | 2,197 | 345 | 147 | 105 | .583 | 345 | 3.12 | 25 | 11 | 0 | 2332.0 | 2,080 | 808 | 901 | 191 | 658 | 75 | 0 | 16 | 9,549 | 128 | 8.48 | 2.54 | 3.34 | 0.74 | 23.0 | 6.9 | 1.17 | .294 | 3.48 | 8.03 |
| 19 | | D. Wells | 2,195 | 658 | 239 | 155 | .607 | 487 | 4.11 | 54 | 12 | 13 | 3433.2 | 3,620 | 1,569 | 1,693 | 407 | 715 | 83 | 65 | 65 | 14,379 | 98 | 5.75 | 1.87 | 3.07 | 1.07 | 15.3 | 5.0 | 1.26 | .293 | 4.44 | 9.49 |
| 20 | | J. Peavy | 2,183 | 376 | 152 | 125 | .549 | 375 | 3.60 | 15 | 6 | 0 | 2358.0 | 2,110 | 944 | 995 | 253 | 702 | 78 | 0 | 42 | 9,750 | 45 | 8.33 | 2.68 | 3.11 | 0.97 | 22.4 | 7.2 | 1.19 | .284 | 3.80 | 8.05 |
| 21 | | T. Wakefield | 2,156 | 627 | 200 | 180 | .526 | 463 | 4.41 | 33 | 6 | 22 | 3226.1 | 3,152 | 1,582 | 1,791 | 418 | 1,205 | 186 | 78 | 33 | 13,939 | 134 | 6.01 | 3.36 | 1.79 | 1.17 | 15.5 | 8.6 | 1.35 | .274 | 5.00 | 8.79 |
| 22 | | R. Halladay | 2,117 | 416 | 203 | 105 | .659 | 390 | 3.38 | 67 | 20 | 1 | 2749.1 | 2,646 | 1,034 | 1,135 | 236 | 592 | 81 | 6 | 28 | 11,287 | 56 | 6.93 | 1.94 | 3.58 | 0.77 | 18.8 | 5.2 | 1.18 | .292 | 3.72 | 8.66 |
| 23 | | J. Lackey | 2,098 | 408 | 172 | 134 | .562 | 407 | 3.91 | 18 | 8 | 0 | 2612.0 | 2,655 | 1,135 | 1,237 | 277 | 749 | 119 | 0 | 29 | 11,076 | 113 | 7.23 | 2.58 | 2.80 | 0.95 | 18.9 | 6.8 | 1.30 | .304 | 4.26 | 9.15 |
| 24 | | K. Millwood | 2,083 | 451 | 169 | 152 | .526 | 443 | 4.11 | 22 | 6 | 0 | 2720.1 | 2,770 | 1,243 | 1,357 | 296 | 843 | 74 | 3 | 46 | 11,616 | 67 | 6.89 | 2.79 | 2.47 | 0.98 | 17.9 | 7.3 | 1.33 | .297 | 4.49 | 9.16 |
| 25 |  | J. Verlander | 2,082 | 338 | 166 | 103 | .617 | 338 | 3.53 | 22 | 7 | 0 | 2243.2 | 2,007 | 880 | 957 | 204 | 679 | 79 | 0 | 22 | 9,297 | 73 | 8.35 | 2.72 | 3.07 | 0.82 | 22.4 | 7.3 | 1.20 | .288 | 3.84 | 8.05 |
StatMuse has game-level data for strikeouts going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
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