Between January 1, 1977 and July 27, 2004, Roger Clemens fanned the most hitters, with 4,232 strikeouts.
- Regular season
| NAME | SO | G | W | L | W% | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | H/9 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | R. Clemens | 4,232 | 627 | 321 | 163 | .663 | 626 | 3.18 | 117 | 46 | 0 | 4408.0 | 3,778 | 1,558 | 1,715 | 333 | 1,430 | 145 | 0 | 56 | 18,184 | 127 | 8.64 | 2.92 | 2.96 | 0.68 | 23.3 | 7.9 | 1.18 | .286 | 3.50 | 7.71 |
| 2 |  | R. Johnson | 4,045 | 476 | 240 | 122 | .663 | 466 | 3.08 | 91 | 37 | 2 | 3273.2 | 2,540 | 1,122 | 1,269 | 293 | 1,288 | 154 | 5 | 23 | 13,493 | 94 | 11.12 | 3.54 | 3.14 | 0.81 | 30.0 | 9.5 | 1.17 | .291 | 3.49 | 6.98 |
| 3 |  | N. Ryan | 3,629 | 513 | 202 | 176 | .534 | 513 | 3.24 | 106 | 31 | 0 | 3451.0 | 2,584 | 1,243 | 1,421 | 211 | 1,615 | 96 | 0 | 53 | 14,388 | 195 | 9.46 | 4.21 | 2.25 | 0.55 | 25.2 | 11.2 | 1.22 | .269 | 3.71 | 6.74 |
| 4 |  | G. Maddux | 2,858 | 596 | 299 | 170 | .638 | 592 | 2.93 | 105 | 35 | 0 | 4104.1 | 3,768 | 1,334 | 1,522 | 257 | 857 | 115 | 3 | 157 | 16,674 | 55 | 6.27 | 1.88 | 3.33 | 0.56 | 17.1 | 5.1 | 1.13 | .279 | 3.34 | 8.26 |
| 5 |  | C. Schilling | 2,670 | 470 | 175 | 121 | .591 | 358 | 3.33 | 81 | 19 | 13 | 2724.2 | 2,424 | 1,009 | 1,071 | 274 | 626 | 42 | 60 | 41 | 11,060 | 69 | 8.82 | 2.07 | 4.27 | 0.91 | 24.1 | 5.7 | 1.12 | .289 | 3.54 | 8.01 |
| 6 | | D. Cone | 2,668 | 450 | 194 | 126 | .606 | 419 | 3.47 | 56 | 22 | 1 | 2898.2 | 2,504 | 1,116 | 1,222 | 258 | 1,137 | 106 | 9 | 42 | 12,184 | 149 | 8.28 | 3.53 | 2.35 | 0.80 | 21.9 | 9.3 | 1.26 | .280 | 3.79 | 7.77 |
| 7 | | C. Finley | 2,610 | 524 | 200 | 173 | .536 | 467 | 3.85 | 63 | 15 | 0 | 3197.1 | 3,069 | 1,366 | 1,517 | 304 | 1,332 | 76 | 24 | 36 | 13,638 | 130 | 7.35 | 3.75 | 1.96 | 0.86 | 19.1 | 9.8 | 1.38 | .297 | 4.27 | 8.64 |
| 8 |  | P. Martinez | 2,558 | 376 | 177 | 71 | .714 | 309 | 2.68 | 41 | 15 | 3 | 2215.2 | 1,676 | 660 | 733 | 166 | 592 | 108 | 23 | 21 | 8,851 | 51 | 10.39 | 2.40 | 4.32 | 0.67 | 28.9 | 6.7 | 1.02 | .278 | 2.98 | 6.81 |
| 9 |  | J. Morris | 2,478 | 549 | 254 | 186 | .577 | 527 | 3.90 | 175 | 28 | 0 | 3824.0 | 3,567 | 1,657 | 1,815 | 389 | 1,390 | 58 | 10 | 99 | 16,120 | 205 | 5.83 | 3.27 | 1.78 | 0.92 | 15.4 | 8.6 | 1.30 | .269 | 4.27 | 8.40 |
| 10 | | M. Langston | 2,464 | 457 | 179 | 158 | .531 | 428 | 3.97 | 81 | 18 | 0 | 2962.2 | 2,723 | 1,306 | 1,438 | 311 | 1,289 | 46 | 3 | 34 | 12,562 | 89 | 7.49 | 3.92 | 1.91 | 0.94 | 19.6 | 10.3 | 1.35 | .285 | 4.37 | 8.27 |
| 11 |  | J. Smoltz | 2,368 | 572 | 163 | 120 | .576 | 361 | 3.27 | 47 | 14 | 131 | 2667.2 | 2,290 | 968 | 1,060 | 213 | 821 | 40 | 178 | 60 | 10,932 | 124 | 7.99 | 2.77 | 2.88 | 0.72 | 21.7 | 7.5 | 1.17 | .277 | 3.58 | 7.73 |
| 12 | | K. Brown | 2,312 | 464 | 204 | 132 | .607 | 454 | 3.19 | 72 | 17 | 0 | 3131.2 | 2,923 | 1,109 | 1,275 | 199 | 865 | 130 | 1 | 41 | 12,981 | 98 | 6.64 | 2.49 | 2.67 | 0.57 | 17.8 | 6.7 | 1.21 | .287 | 3.66 | 8.40 |
| 13 | | D. Gooden | 2,293 | 430 | 194 | 112 | .634 | 410 | 3.51 | 68 | 24 | 3 | 2800.2 | 2,564 | 1,091 | 1,198 | 210 | 954 | 78 | 4 | 42 | 11,705 | 76 | 7.37 | 3.07 | 2.40 | 0.67 | 19.6 | 8.2 | 1.26 | .288 | 3.85 | 8.24 |
| 14 | | T. Glavine | 2,212 | 559 | 259 | 165 | .611 | 559 | 3.40 | 53 | 23 | 0 | 3676.0 | 3,507 | 1,387 | 1,532 | 277 | 1,244 | 52 | 0 | 122 | 15,431 | 61 | 5.42 | 3.05 | 1.78 | 0.68 | 14.3 | 8.1 | 1.29 | .277 | 3.75 | 8.59 |
| 15 | | M. Mussina | 2,201 | 404 | 208 | 116 | .642 | 404 | 3.60 | 54 | 21 | 0 | 2776.0 | 2,628 | 1,109 | 1,181 | 293 | 620 | 35 | 0 | 22 | 11,315 | 59 | 7.14 | 2.01 | 3.55 | 0.95 | 19.5 | 5.5 | 1.17 | .286 | 3.83 | 8.52 |
| 16 | | B. Blyleven | 2,155 | 440 | 179 | 149 | .546 | 436 | 3.64 | 127 | 30 | 0 | 3061.0 | 2,933 | 1,237 | 1,357 | 302 | 838 | 104 | 1 | 42 | 12,733 | 76 | 6.34 | 2.46 | 2.57 | 0.89 | 16.9 | 6.6 | 1.23 | .282 | 3.99 | 8.62 |
| 17 | | D. Martinez | 2,131 | 688 | 244 | 191 | .561 | 560 | 3.70 | 121 | 30 | 8 | 3972.0 | 3,874 | 1,635 | 1,827 | 371 | 1,157 | 122 | 50 | 70 | 16,648 | 83 | 4.83 | 2.62 | 1.84 | 0.84 | 12.8 | 6.9 | 1.27 | .272 | 4.14 | 8.78 |
| 18 | | C. Hough | 2,098 | 643 | 188 | 195 | .491 | 440 | 3.84 | 107 | 13 | 31 | 3406.0 | 2,998 | 1,452 | 1,655 | 351 | 1,453 | 147 | 117 | 37 | 14,495 | 160 | 5.54 | 3.84 | 1.44 | 0.93 | 14.5 | 10.0 | 1.31 | .253 | 4.37 | 7.92 |
| 19 | | F. Valenzuela | 2,074 | 453 | 173 | 153 | .531 | 424 | 3.54 | 113 | 31 | 2 | 2930.0 | 2,718 | 1,154 | 1,303 | 226 | 1,151 | 25 | 10 | 65 | 12,398 | 119 | 6.37 | 3.54 | 1.80 | 0.69 | 16.7 | 9.3 | 1.32 | .279 | 4.00 | 8.35 |
| 20 | | D. Eckersley | 2,049 | 1,001 | 171 | 152 | .529 | 307 | 3.57 | 85 | 15 | 387 | 2899.2 | 2,774 | 1,149 | 1,239 | 318 | 570 | 63 | 569 | 80 | 11,919 | 18 | 6.36 | 1.77 | 3.59 | 0.99 | 17.2 | 4.8 | 1.15 | .275 | 3.85 | 8.61 |
| 21 | | F. Tanana | 2,041 | 527 | 189 | 196 | .491 | 510 | 3.89 | 90 | 22 | 1 | 3347.2 | 3,358 | 1,447 | 1,627 | 374 | 1,024 | 105 | 7 | 101 | 14,235 | 100 | 5.49 | 2.75 | 1.99 | 1.01 | 14.3 | 7.2 | 1.31 | .279 | 4.37 | 9.03 |
| 22 |  | S. Carlton | 2,025 | 359 | 161 | 118 | .577 | 345 | 3.34 | 96 | 22 | 1 | 2513.2 | 2,263 | 932 | 1,076 | 215 | 872 | 24 | 6 | 73 | 10,441 | 92 | 7.25 | 3.12 | 2.32 | 0.77 | 19.4 | 8.4 | 1.25 | .280 | 3.85 | 8.10 |
| 23 | | O. Hershiser | 2,014 | 510 | 204 | 150 | .576 | 466 | 3.48 | 68 | 25 | 5 | 3130.1 | 2,939 | 1,211 | 1,367 | 235 | 1,007 | 117 | 19 | 108 | 13,150 | 121 | 5.79 | 2.90 | 2.00 | 0.68 | 15.3 | 7.7 | 1.26 | .277 | 3.93 | 8.45 |
| 24 | | A. Benes | 2,000 | 403 | 155 | 139 | .527 | 387 | 3.97 | 21 | 9 | 1 | 2505.1 | 2,377 | 1,106 | 1,206 | 289 | 909 | 55 | 6 | 52 | 10,645 | 63 | 7.18 | 3.27 | 2.20 | 1.04 | 18.8 | 8.5 | 1.31 | .282 | 4.33 | 8.54 |
| 25 | | K. Appier | 1,994 | 414 | 169 | 137 | .552 | 402 | 3.74 | 34 | 12 | 0 | 2595.1 | 2,425 | 1,078 | 1,168 | 232 | 933 | 79 | 2 | 51 | 10,958 | 106 | 6.91 | 3.24 | 2.14 | 0.80 | 18.2 | 8.5 | 1.29 | .284 | 4.05 | 8.41 |
StatMuse has game-level data for strikeouts going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
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