Between January 1, 1986 and December 31, 2005, Randy Johnson struck out the most hitters, with 4,372 strikeouts.
| NAME | SO | G | W | L | W% | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | H/9 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | R. Johnson | 4,372 | 523 | 263 | 136 | .659 | 513 | 3.11 | 96 | 37 | 2 | 3593.2 | 2,819 | 1,243 | 1,405 | 333 | 1,349 | 168 | 5 | 25 | 14,784 | 98 | 10.95 | 3.38 | 3.24 | 0.83 | 29.6 | 9.1 | 1.16 | .290 | 3.52 | 7.06 |
| 2 |  | R. Clemens | 4,302 | 636 | 325 | 163 | .666 | 636 | 3.08 | 110 | 44 | 0 | 4472.2 | 3,768 | 1,532 | 1,694 | 329 | 1,454 | 145 | 0 | 59 | 18,387 | 128 | 8.66 | 2.93 | 2.96 | 0.66 | 23.4 | 7.9 | 1.17 | .283 | 3.41 | 7.58 |
| 3 |  | G. Maddux | 3,052 | 643 | 318 | 189 | .627 | 639 | 3.01 | 108 | 35 | 0 | 4406.1 | 4,082 | 1,476 | 1,675 | 298 | 907 | 125 | 3 | 162 | 17,925 | 63 | 6.23 | 1.85 | 3.36 | 0.61 | 17.0 | 5.1 | 1.13 | .279 | 3.42 | 8.34 |
| 4 |  | P. Martinez | 2,861 | 419 | 197 | 84 | .701 | 352 | 2.72 | 46 | 17 | 3 | 2513.0 | 1,905 | 759 | 835 | 194 | 662 | 119 | 23 | 24 | 10,032 | 57 | 10.25 | 2.37 | 4.32 | 0.69 | 28.5 | 6.6 | 1.02 | .276 | 2.99 | 6.82 |
| 5 |  | C. Schilling | 2,832 | 514 | 192 | 131 | .594 | 381 | 3.40 | 82 | 19 | 22 | 2906.0 | 2,613 | 1,098 | 1,160 | 298 | 660 | 47 | 81 | 41 | 11,817 | 71 | 8.77 | 2.04 | 4.29 | 0.92 | 24.0 | 5.6 | 1.13 | .290 | 3.59 | 8.09 |
| 6 | | D. Cone | 2,668 | 450 | 194 | 126 | .606 | 419 | 3.47 | 56 | 22 | 1 | 2898.2 | 2,504 | 1,116 | 1,222 | 258 | 1,137 | 106 | 9 | 42 | 12,184 | 149 | 8.28 | 3.53 | 2.35 | 0.80 | 21.9 | 9.3 | 1.26 | .280 | 3.79 | 7.77 |
| 7 | | C. Finley | 2,610 | 524 | 200 | 173 | .536 | 467 | 3.85 | 63 | 15 | 0 | 3197.1 | 3,069 | 1,366 | 1,517 | 304 | 1,332 | 76 | 24 | 36 | 13,638 | 130 | 7.35 | 3.75 | 1.96 | 0.86 | 19.1 | 9.8 | 1.38 | .297 | 4.27 | 8.64 |
| 8 |  | J. Smoltz | 2,567 | 635 | 177 | 128 | .580 | 394 | 3.26 | 50 | 15 | 154 | 2929.1 | 2,537 | 1,060 | 1,157 | 234 | 882 | 41 | 204 | 68 | 11,997 | 130 | 7.89 | 2.71 | 2.91 | 0.72 | 21.4 | 7.4 | 1.17 | .278 | 3.55 | 7.79 |
| 9 | | M. Mussina | 2,400 | 443 | 224 | 127 | .638 | 443 | 3.64 | 56 | 23 | 0 | 3013.0 | 2,874 | 1,219 | 1,296 | 323 | 684 | 43 | 0 | 23 | 12,314 | 63 | 7.17 | 2.04 | 3.51 | 0.96 | 19.5 | 5.6 | 1.18 | .288 | 3.87 | 8.58 |
| 10 | | K. Brown | 2,397 | 486 | 211 | 144 | .594 | 476 | 3.28 | 72 | 17 | 0 | 3256.1 | 3,079 | 1,185 | 1,357 | 208 | 901 | 139 | 1 | 42 | 13,542 | 108 | 6.62 | 2.49 | 2.66 | 0.57 | 17.7 | 6.7 | 1.22 | .290 | 3.75 | 8.51 |
| 11 | | T. Glavine | 2,350 | 603 | 275 | 184 | .599 | 603 | 3.44 | 55 | 24 | 0 | 3951.2 | 3,810 | 1,512 | 1,664 | 300 | 1,337 | 55 | 0 | 132 | 16,626 | 62 | 5.35 | 3.05 | 1.76 | 0.68 | 14.1 | 8.0 | 1.30 | .279 | 3.79 | 8.68 |
| 12 | | M. Langston | 2,188 | 398 | 155 | 134 | .536 | 371 | 3.94 | 74 | 16 | 0 | 2611.0 | 2,413 | 1,144 | 1,254 | 273 | 1,080 | 36 | 3 | 27 | 11,020 | 82 | 7.54 | 3.72 | 2.03 | 0.94 | 19.9 | 9.8 | 1.34 | .288 | 4.32 | 8.32 |
| 13 | | D. Wells | 2,081 | 618 | 227 | 143 | .614 | 447 | 4.06 | 54 | 12 | 13 | 3206.1 | 3,337 | 1,446 | 1,564 | 374 | 665 | 80 | 65 | 60 | 13,395 | 100 | 5.84 | 1.87 | 3.13 | 1.05 | 15.5 | 5.0 | 1.25 | .291 | 4.39 | 9.37 |
| 14 | | A. Benes | 2,000 | 403 | 155 | 139 | .527 | 387 | 3.97 | 21 | 9 | 1 | 2505.1 | 2,377 | 1,106 | 1,206 | 289 | 909 | 55 | 6 | 52 | 10,645 | 63 | 7.18 | 3.27 | 2.20 | 1.04 | 18.8 | 8.5 | 1.31 | .282 | 4.33 | 8.54 |
| 15 | | K. Appier | 1,994 | 414 | 169 | 137 | .552 | 402 | 3.74 | 34 | 12 | 0 | 2595.1 | 2,425 | 1,078 | 1,168 | 232 | 933 | 79 | 2 | 51 | 10,958 | 106 | 6.91 | 3.24 | 2.14 | 0.80 | 18.2 | 8.5 | 1.29 | .284 | 4.05 | 8.41 |
| 16 | | A. Leiter | 1,974 | 419 | 162 | 132 | .551 | 382 | 3.80 | 16 | 10 | 2 | 2391.0 | 2,152 | 1,010 | 1,101 | 198 | 1,163 | 117 | 9 | 53 | 10,334 | 63 | 7.43 | 4.38 | 1.70 | 0.75 | 19.1 | 11.3 | 1.39 | .284 | 4.14 | 8.10 |
| 17 | | B. Witt | 1,955 | 430 | 142 | 157 | .475 | 397 | 4.83 | 47 | 11 | 0 | 2465.0 | 2,493 | 1,324 | 1,449 | 252 | 1,375 | 39 | 13 | 37 | 11,003 | 128 | 7.14 | 5.02 | 1.42 | 0.92 | 17.8 | 12.5 | 1.57 | .304 | 5.29 | 9.10 |
| 18 | | H. Nomo | 1,915 | 320 | 123 | 109 | .530 | 318 | 4.21 | 16 | 9 | 0 | 1972.0 | 1,758 | 923 | 984 | 248 | 904 | 38 | 0 | 31 | 8,435 | 109 | 8.74 | 4.13 | 2.12 | 1.13 | 22.7 | 10.7 | 1.35 | .283 | 4.49 | 8.02 |
| 19 | | J. Moyer | 1,884 | 538 | 205 | 152 | .574 | 485 | 4.16 | 28 | 8 | 0 | 3139.2 | 3,227 | 1,450 | 1,568 | 381 | 895 | 107 | 14 | 54 | 13,341 | 48 | 5.40 | 2.57 | 2.11 | 1.09 | 14.1 | 6.7 | 1.31 | .283 | 4.49 | 9.25 |
| 20 | | T. Gordon | 1,802 | 750 | 127 | 115 | .525 | 203 | 3.93 | 18 | 4 | 116 | 1977.1 | 1,762 | 863 | 949 | 157 | 922 | 35 | 275 | 52 | 8,486 | 102 | 8.20 | 4.20 | 1.95 | 0.71 | 21.2 | 10.9 | 1.36 | .288 | 4.32 | 8.02 |
| 21 | | J. Burkett | 1,766 | 445 | 166 | 136 | .550 | 423 | 4.31 | 21 | 6 | 1 | 2648.1 | 2,866 | 1,268 | 1,374 | 257 | 700 | 90 | 8 | 59 | 11,324 | 33 | 6.00 | 2.38 | 2.52 | 0.87 | 15.6 | 6.2 | 1.35 | .307 | 4.67 | 9.74 |
| 22 | | K. Rogers | 1,751 | 687 | 190 | 131 | .592 | 400 | 4.21 | 36 | 9 | 28 | 2862.0 | 2,985 | 1,340 | 1,488 | 286 | 1,017 | 108 | 132 | 48 | 12,374 | 69 | 5.51 | 3.20 | 1.72 | 0.90 | 14.2 | 8.2 | 1.40 | .293 | 4.68 | 9.39 |
| 23 | | D. Gooden | 1,749 | 364 | 153 | 99 | .607 | 344 | 3.83 | 45 | 13 | 3 | 2306.0 | 2,205 | 981 | 1,075 | 190 | 812 | 74 | 4 | 36 | 9,761 | 67 | 6.83 | 3.17 | 2.15 | 0.74 | 17.9 | 8.3 | 1.31 | .291 | 4.20 | 8.61 |
| 24 | | O. Hershiser | 1,702 | 421 | 174 | 139 | .556 | 412 | 3.67 | 51 | 16 | 2 | 2693.0 | 2,593 | 1,098 | 1,223 | 217 | 883 | 107 | 4 | 95 | 11,389 | 107 | 5.69 | 2.95 | 1.93 | 0.73 | 14.9 | 7.8 | 1.29 | .280 | 4.09 | 8.67 |
| 25 | | T. Candiotti | 1,691 | 433 | 145 | 158 | .479 | 396 | 3.72 | 66 | 10 | 0 | 2637.0 | 2,562 | 1,091 | 1,257 | 241 | 857 | 83 | 10 | 31 | 11,188 | 119 | 5.77 | 2.92 | 1.97 | 0.82 | 15.1 | 7.7 | 1.30 | .279 | 4.29 | 8.74 |
StatMuse has game-level data for strikeouts going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
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