Between January 1, 1987 and December 31, 2007, Randy Johnson struck out the most hitters, with 4,616 strikeouts.
| NAME | SO | G | W | L | W% | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | H/9 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | R. Johnson | 4,616 | 566 | 284 | 150 | .654 | 556 | 3.22 | 98 | 37 | 2 | 3855.1 | 3,065 | 1,381 | 1,556 | 368 | 1,422 | 182 | 5 | 29 | 15,877 | 102 | 10.78 | 3.32 | 3.25 | 0.86 | 29.1 | 9.0 | 1.16 | .290 | 3.63 | 7.16 |
| 2 |  | R. Clemens | 4,234 | 640 | 314 | 171 | .647 | 639 | 3.12 | 100 | 43 | 0 | 4431.0 | 3,777 | 1,537 | 1,703 | 324 | 1,447 | 150 | 0 | 60 | 18,261 | 127 | 8.60 | 2.94 | 2.93 | 0.66 | 23.2 | 7.9 | 1.18 | .285 | 3.46 | 7.67 |
| 3 |  | G. Maddux | 3,253 | 705 | 345 | 210 | .622 | 702 | 3.10 | 108 | 35 | 0 | 4783.1 | 4,478 | 1,646 | 1,856 | 329 | 958 | 130 | 2 | 170 | 19,473 | 66 | 6.12 | 1.80 | 3.40 | 0.62 | 16.7 | 4.9 | 1.14 | .280 | 3.49 | 8.43 |
| 4 |  | C. Schilling | 3,116 | 569 | 216 | 146 | .597 | 436 | 3.46 | 83 | 20 | 22 | 3261.0 | 2,998 | 1,253 | 1,318 | 347 | 711 | 52 | 81 | 43 | 13,284 | 72 | 8.60 | 1.96 | 4.38 | 0.96 | 23.5 | 5.4 | 1.14 | .293 | 3.64 | 8.27 |
| 5 |  | P. Martinez | 3,030 | 447 | 209 | 93 | .692 | 380 | 2.80 | 46 | 17 | 3 | 2673.2 | 2,046 | 833 | 918 | 213 | 708 | 131 | 23 | 27 | 10,710 | 60 | 10.20 | 2.38 | 4.28 | 0.72 | 28.3 | 6.6 | 1.03 | .277 | 3.09 | 6.89 |
| 6 |  | J. Smoltz | 2,975 | 702 | 207 | 145 | .588 | 461 | 3.26 | 53 | 16 | 154 | 3367.0 | 2,954 | 1,221 | 1,328 | 275 | 984 | 54 | 204 | 81 | 13,810 | 143 | 7.95 | 2.63 | 3.02 | 0.74 | 21.5 | 7.1 | 1.17 | .281 | 3.55 | 7.90 |
| 7 | | M. Mussina | 2,663 | 503 | 250 | 144 | .635 | 502 | 3.70 | 57 | 23 | 0 | 3362.1 | 3,246 | 1,383 | 1,474 | 359 | 754 | 52 | 0 | 26 | 13,774 | 67 | 7.13 | 2.02 | 3.53 | 0.96 | 19.3 | 5.5 | 1.19 | .290 | 3.95 | 8.69 |
| 8 | | D. Cone | 2,647 | 439 | 194 | 126 | .606 | 419 | 3.45 | 56 | 22 | 1 | 2876.0 | 2,475 | 1,102 | 1,208 | 256 | 1,124 | 105 | 4 | 41 | 12,076 | 146 | 8.28 | 3.52 | 2.35 | 0.80 | 21.9 | 9.3 | 1.25 | .279 | 3.78 | 7.75 |
| 9 | | C. Finley | 2,573 | 499 | 197 | 172 | .534 | 467 | 3.85 | 63 | 15 | 0 | 3151.0 | 3,029 | 1,349 | 1,500 | 302 | 1,309 | 75 | 17 | 35 | 13,440 | 128 | 7.35 | 3.74 | 1.97 | 0.86 | 19.1 | 9.7 | 1.38 | .297 | 4.28 | 8.65 |
| 10 | | T. Glavine | 2,570 | 669 | 303 | 199 | .604 | 669 | 3.51 | 56 | 25 | 0 | 4350.0 | 4,231 | 1,695 | 1,860 | 345 | 1,463 | 65 | 0 | 141 | 18,323 | 65 | 5.32 | 3.03 | 1.76 | 0.71 | 14.0 | 8.0 | 1.31 | .280 | 3.85 | 8.75 |
| 11 | | K. Brown | 2,393 | 485 | 210 | 144 | .593 | 475 | 3.27 | 72 | 17 | 0 | 3251.1 | 3,073 | 1,183 | 1,355 | 208 | 901 | 139 | 1 | 42 | 13,523 | 108 | 6.62 | 2.49 | 2.66 | 0.58 | 17.7 | 6.7 | 1.22 | .290 | 3.75 | 8.51 |
| 12 | | D. Wells | 2,201 | 660 | 239 | 157 | .604 | 489 | 4.13 | 54 | 12 | 13 | 3439.0 | 3,635 | 1,578 | 1,702 | 407 | 719 | 83 | 65 | 65 | 14,413 | 101 | 5.76 | 1.88 | 3.06 | 1.07 | 15.3 | 5.0 | 1.27 | .293 | 4.45 | 9.51 |
| 13 | | J. Moyer | 2,080 | 588 | 223 | 174 | .562 | 535 | 4.19 | 30 | 8 | 0 | 3463.0 | 3,570 | 1,613 | 1,744 | 434 | 970 | 114 | 14 | 61 | 14,707 | 50 | 5.41 | 2.52 | 2.14 | 1.13 | 14.1 | 6.6 | 1.31 | .282 | 4.53 | 9.28 |
| 14 | | A. Benes | 2,000 | 403 | 155 | 139 | .527 | 387 | 3.97 | 21 | 9 | 1 | 2505.1 | 2,377 | 1,106 | 1,206 | 289 | 909 | 55 | 6 | 52 | 10,645 | 63 | 7.18 | 3.27 | 2.20 | 1.04 | 18.8 | 8.5 | 1.31 | .282 | 4.33 | 8.54 |
| 15 | | K. Appier | 1,994 | 414 | 169 | 137 | .552 | 402 | 3.74 | 34 | 12 | 0 | 2595.1 | 2,425 | 1,078 | 1,168 | 232 | 933 | 79 | 2 | 51 | 10,958 | 106 | 6.91 | 3.24 | 2.14 | 0.80 | 18.2 | 8.5 | 1.29 | .284 | 4.05 | 8.41 |
| 16 | | A. Leiter | 1,974 | 419 | 162 | 132 | .551 | 382 | 3.80 | 16 | 10 | 2 | 2391.0 | 2,152 | 1,010 | 1,101 | 198 | 1,163 | 117 | 9 | 53 | 10,334 | 63 | 7.43 | 4.38 | 1.70 | 0.75 | 19.1 | 11.3 | 1.39 | .284 | 4.14 | 8.10 |
| 17 | | M. Langston | 1,943 | 361 | 143 | 120 | .544 | 335 | 3.85 | 65 | 16 | 0 | 2371.2 | 2,179 | 1,015 | 1,112 | 243 | 957 | 32 | 2 | 26 | 9,963 | 72 | 7.37 | 3.63 | 2.03 | 0.92 | 19.5 | 9.6 | 1.32 | .285 | 4.22 | 8.27 |
| 18 | | H. Nomo | 1,915 | 320 | 123 | 109 | .530 | 318 | 4.21 | 16 | 9 | 0 | 1972.0 | 1,758 | 923 | 984 | 248 | 904 | 38 | 0 | 31 | 8,435 | 109 | 8.74 | 4.13 | 2.12 | 1.13 | 22.7 | 10.7 | 1.35 | .283 | 4.49 | 8.02 |
| 19 | | T. Gordon | 1,902 | 853 | 133 | 121 | .524 | 203 | 3.93 | 18 | 4 | 156 | 2076.2 | 1,855 | 906 | 993 | 173 | 957 | 38 | 339 | 56 | 8,909 | 106 | 8.24 | 4.15 | 1.99 | 0.75 | 21.3 | 10.7 | 1.35 | .288 | 4.30 | 8.04 |
| 20 | | K. Rogers | 1,886 | 732 | 210 | 143 | .595 | 444 | 4.19 | 36 | 9 | 28 | 3129.0 | 3,245 | 1,458 | 1,621 | 317 | 1,104 | 118 | 133 | 50 | 13,498 | 75 | 5.42 | 3.18 | 1.71 | 0.91 | 14.0 | 8.2 | 1.39 | .291 | 4.66 | 9.33 |
| 21 | | A. Pettitte | 1,844 | 403 | 201 | 113 | .640 | 393 | 3.83 | 25 | 4 | 0 | 2527.2 | 2,636 | 1,077 | 1,196 | 211 | 790 | 37 | 3 | 33 | 10,736 | 51 | 6.57 | 2.81 | 2.33 | 0.75 | 17.2 | 7.4 | 1.36 | .309 | 4.26 | 9.39 |
| 22 | | J. Vazquez | 1,815 | 322 | 115 | 113 | .504 | 320 | 4.28 | 22 | 7 | 0 | 2062.1 | 2,056 | 981 | 1,056 | 275 | 543 | 69 | 1 | 42 | 8,690 | 55 | 7.92 | 2.37 | 3.34 | 1.20 | 20.9 | 6.2 | 1.26 | .297 | 4.61 | 8.97 |
| 23 | | T. Wakefield | 1,790 | 511 | 168 | 146 | .535 | 370 | 4.33 | 29 | 6 | 22 | 2621.0 | 2,545 | 1,262 | 1,433 | 337 | 1,012 | 150 | 62 | 29 | 11,326 | 92 | 6.15 | 3.48 | 1.77 | 1.16 | 15.8 | 8.9 | 1.36 | .275 | 4.92 | 8.74 |
| 24 | | B. Witt | 1,781 | 399 | 131 | 148 | .470 | 366 | 4.79 | 47 | 11 | 0 | 2307.1 | 2,363 | 1,228 | 1,345 | 234 | 1,232 | 36 | 13 | 35 | 10,262 | 106 | 6.95 | 4.81 | 1.45 | 0.91 | 17.4 | 12.0 | 1.56 | .305 | 5.25 | 9.22 |
| 25 | | J. Burkett | 1,766 | 445 | 166 | 136 | .550 | 423 | 4.31 | 21 | 6 | 1 | 2648.1 | 2,866 | 1,268 | 1,374 | 257 | 700 | 90 | 8 | 59 | 11,324 | 33 | 6.00 | 2.38 | 2.52 | 0.87 | 15.6 | 6.2 | 1.35 | .307 | 4.67 | 9.74 |
StatMuse has game-level data for strikeouts going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
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 Braves - y | 94 | 68 | .580 | |
 Phillies - w | 88 | 74 | .543 | 6.0 |
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