Between June 8, 1987 and May 8, 2019, Randy Johnson struck out the most hitters, with 4,875 strikeouts.
| NAME | SO | G | W | L | W% | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | H/9 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | R. Johnson | 4,875 | 618 | 303 | 166 | .646 | 603 | 3.29 | 100 | 37 | 2 | 4135.1 | 3,346 | 1,513 | 1,703 | 411 | 1,497 | 190 | 7 | 37 | 17,067 | 109 | 10.61 | 3.26 | 3.26 | 0.89 | 28.6 | 8.8 | 1.17 | .291 | 3.71 | 7.28 |
| 2 |  | R. Clemens | 4,152 | 628 | 310 | 166 | .651 | 627 | 3.12 | 95 | 41 | 0 | 4337.1 | 3,698 | 1,505 | 1,668 | 316 | 1,412 | 146 | 0 | 58 | 17,875 | 125 | 8.62 | 2.93 | 2.94 | 0.66 | 23.2 | 7.9 | 1.18 | .285 | 3.46 | 7.67 |
| 3 |  | G. Maddux | 3,308 | 726 | 349 | 218 | .616 | 724 | 3.12 | 108 | 35 | 0 | 4911.0 | 4,610 | 1,701 | 1,922 | 345 | 958 | 133 | 2 | 170 | 19,983 | 65 | 6.06 | 1.76 | 3.45 | 0.63 | 16.6 | 4.8 | 1.13 | .280 | 3.52 | 8.45 |
| 4 |  | P. Martinez | 3,154 | 476 | 219 | 100 | .687 | 409 | 2.93 | 46 | 17 | 3 | 2827.1 | 2,221 | 919 | 1,006 | 239 | 760 | 141 | 23 | 30 | 11,394 | 62 | 10.04 | 2.42 | 4.15 | 0.76 | 27.7 | 6.7 | 1.05 | .279 | 3.20 | 7.07 |
| 5 |  | C. Schilling | 3,116 | 569 | 216 | 146 | .597 | 436 | 3.46 | 83 | 20 | 22 | 3261.0 | 2,998 | 1,253 | 1,318 | 347 | 711 | 52 | 81 | 43 | 13,284 | 72 | 8.60 | 1.96 | 4.38 | 0.96 | 23.5 | 5.4 | 1.14 | .293 | 3.64 | 8.27 |
| 6 |  | J. Smoltz | 3,084 | 723 | 213 | 155 | .579 | 481 | 3.33 | 53 | 16 | 154 | 3473.0 | 3,074 | 1,284 | 1,391 | 288 | 1,010 | 57 | 204 | 84 | 14,271 | 145 | 7.99 | 2.62 | 3.05 | 0.75 | 21.6 | 7.1 | 1.18 | .283 | 3.60 | 7.97 |
| 7 |  | CC Sabathia | 3,007 | 543 | 248 | 154 | .617 | 543 | 3.69 | 38 | 12 | 0 | 3495.1 | 3,312 | 1,435 | 1,570 | 361 | 1,069 | 120 | 0 | 44 | 14,626 | 74 | 7.74 | 2.75 | 2.81 | 0.93 | 20.6 | 7.3 | 1.25 | .293 | 4.04 | 8.53 |
| 8 | | M. Mussina | 2,813 | 537 | 270 | 153 | .638 | 536 | 3.68 | 57 | 23 | 0 | 3562.2 | 3,460 | 1,458 | 1,559 | 376 | 785 | 60 | 0 | 29 | 14,593 | 71 | 7.11 | 1.98 | 3.58 | 0.95 | 19.3 | 5.4 | 1.19 | .292 | 3.94 | 8.74 |
| 9 |  | J. Verlander | 2,766 | 427 | 209 | 124 | .628 | 427 | 3.38 | 24 | 8 | 0 | 2809.1 | 2,430 | 1,055 | 1,140 | 282 | 820 | 95 | 0 | 27 | 11,544 | 83 | 8.86 | 2.63 | 3.37 | 0.90 | 24.0 | 7.1 | 1.16 | .283 | 3.65 | 7.78 |
| 10 | | D. Cone | 2,617 | 429 | 192 | 124 | .608 | 413 | 3.43 | 55 | 22 | 1 | 2829.0 | 2,428 | 1,078 | 1,180 | 250 | 1,097 | 105 | 3 | 40 | 11,868 | 144 | 8.33 | 3.49 | 2.39 | 0.80 | 22.1 | 9.2 | 1.25 | .279 | 3.75 | 7.72 |
| 11 | | T. Glavine | 2,607 | 682 | 305 | 203 | .600 | 682 | 3.54 | 56 | 25 | 0 | 4413.1 | 4,298 | 1,734 | 1,900 | 356 | 1,500 | 66 | 0 | 145 | 18,604 | 65 | 5.32 | 3.06 | 1.74 | 0.73 | 14.0 | 8.1 | 1.31 | .280 | 3.87 | 8.76 |
| 12 | | C. Finley | 2,548 | 486 | 197 | 170 | .537 | 467 | 3.85 | 63 | 15 | 0 | 3123.1 | 2,999 | 1,336 | 1,483 | 302 | 1,289 | 75 | 10 | 33 | 13,310 | 126 | 7.34 | 3.71 | 1.98 | 0.87 | 19.1 | 9.7 | 1.37 | .297 | 4.27 | 8.64 |
| 13 | | J. Vazquez | 2,536 | 450 | 165 | 160 | .508 | 443 | 4.22 | 28 | 8 | 0 | 2840.0 | 2,784 | 1,331 | 1,431 | 373 | 763 | 88 | 5 | 58 | 11,935 | 76 | 8.04 | 2.42 | 3.32 | 1.18 | 21.2 | 6.4 | 1.25 | .295 | 4.53 | 8.82 |
| 14 |  | B. Colon | 2,535 | 565 | 247 | 188 | .568 | 552 | 4.12 | 38 | 13 | 0 | 3461.2 | 3,593 | 1,584 | 1,719 | 439 | 948 | 64 | 2 | 47 | 14,655 | 45 | 6.59 | 2.46 | 2.67 | 1.14 | 17.3 | 6.5 | 1.31 | .296 | 4.47 | 9.34 |
| 15 |  | M. Scherzer | 2,521 | 346 | 160 | 86 | .650 | 337 | 3.23 | 10 | 5 | 0 | 2170.0 | 1,792 | 779 | 842 | 240 | 593 | 80 | 2 | 18 | 8,801 | 65 | 10.46 | 2.46 | 4.25 | 1.00 | 28.6 | 6.7 | 1.10 | .289 | 3.49 | 7.43 |
| 16 | | A.J. Burnett | 2,513 | 435 | 164 | 157 | .511 | 430 | 3.99 | 24 | 10 | 0 | 2731.1 | 2,519 | 1,210 | 1,328 | 263 | 1,100 | 143 | 1 | 35 | 11,665 | 161 | 8.28 | 3.62 | 2.28 | 0.87 | 21.5 | 9.4 | 1.32 | .295 | 4.38 | 8.30 |
| 17 |  | F. Hernandez | 2,498 | 411 | 169 | 131 | .563 | 410 | 3.36 | 25 | 11 | 0 | 2694.1 | 2,446 | 1,007 | 1,123 | 255 | 785 | 103 | 0 | 16 | 11,117 | 154 | 8.34 | 2.62 | 3.18 | 0.85 | 22.5 | 7.1 | 1.20 | .293 | 3.75 | 8.17 |
| 18 |  | Z. Greinke | 2,485 | 463 | 192 | 119 | .617 | 422 | 3.39 | 16 | 5 | 1 | 2713.1 | 2,526 | 1,021 | 1,098 | 279 | 645 | 65 | 8 | 23 | 11,112 | 84 | 8.24 | 2.14 | 3.85 | 0.93 | 22.4 | 5.8 | 1.17 | .294 | 3.64 | 8.38 |
| 19 | | C. Hamels | 2,459 | 402 | 159 | 114 | .582 | 401 | 3.40 | 17 | 7 | 0 | 2595.2 | 2,313 | 980 | 1,054 | 298 | 724 | 94 | 0 | 42 | 10,662 | 56 | 8.53 | 2.51 | 3.40 | 1.03 | 23.1 | 6.8 | 1.17 | .284 | 3.65 | 8.02 |
| 20 | | A. Pettitte | 2,448 | 531 | 256 | 153 | .626 | 521 | 3.85 | 26 | 4 | 0 | 3316.0 | 3,448 | 1,418 | 1,572 | 288 | 1,031 | 55 | 3 | 42 | 14,074 | 69 | 6.64 | 2.80 | 2.37 | 0.78 | 17.4 | 7.3 | 1.35 | .308 | 4.27 | 9.36 |
| 21 | | K. Brown | 2,393 | 485 | 210 | 144 | .593 | 475 | 3.27 | 72 | 17 | 0 | 3251.1 | 3,073 | 1,183 | 1,355 | 208 | 901 | 139 | 1 | 42 | 13,523 | 108 | 6.62 | 2.49 | 2.66 | 0.58 | 17.7 | 6.7 | 1.22 | .290 | 3.75 | 8.51 |
| 22 | | J. Moyer | 2,341 | 667 | 256 | 202 | .559 | 611 | 4.24 | 32 | 9 | 0 | 3914.0 | 4,062 | 1,844 | 1,989 | 505 | 1,072 | 141 | 14 | 65 | 16,644 | 50 | 5.38 | 2.46 | 2.18 | 1.16 | 14.1 | 6.4 | 1.31 | .283 | 4.57 | 9.34 |
| 23 |  | C. Kershaw | 2,306 | 323 | 155 | 69 | .692 | 321 | 2.41 | 25 | 15 | 0 | 2129.0 | 1,596 | 569 | 621 | 150 | 542 | 31 | 1 | 27 | 8,378 | 81 | 9.75 | 2.29 | 4.25 | 0.63 | 27.5 | 6.5 | 1.00 | .270 | 2.63 | 6.75 |
| 24 | | J. Lackey | 2,294 | 448 | 188 | 147 | .561 | 446 | 3.92 | 18 | 8 | 0 | 2840.1 | 2,862 | 1,237 | 1,347 | 319 | 815 | 133 | 0 | 32 | 12,030 | 125 | 7.27 | 2.58 | 2.81 | 1.01 | 19.1 | 6.8 | 1.29 | .300 | 4.27 | 9.07 |
| 25 | | J. Shields | 2,234 | 407 | 145 | 139 | .511 | 405 | 4.01 | 23 | 9 | 0 | 2616.0 | 2,581 | 1,167 | 1,267 | 361 | 746 | 97 | 1 | 22 | 10,993 | 107 | 7.69 | 2.57 | 2.99 | 1.24 | 20.3 | 6.8 | 1.27 | .294 | 4.36 | 8.88 |
StatMuse has game-level data for strikeouts going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
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