Between September 10, 1972 and September 19, 2005, Nolan Ryan struck out the most batters, with 4,961 strikeouts.
| NAME | SO | G | W | L | W% | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | H/9 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | N. Ryan | 4,961 | 669 | 279 | 241 | .537 | 666 | 3.18 | 194 | 50 | 1 | 4645.0 | 3,415 | 1,643 | 1,880 | 274 | 2,319 | 125 | 3 | 61 | 19,405 | 241 | 9.61 | 4.49 | 2.14 | 0.53 | 25.6 | 12.0 | 1.23 | .268 | 3.64 | 6.62 |
| 2 |  | R. Clemens | 4,497 | 671 | 340 | 172 | .664 | 670 | 3.12 | 118 | 46 | 0 | 4697.1 | 3,991 | 1,631 | 1,798 | 347 | 1,517 | 150 | 0 | 61 | 19,340 | 133 | 8.62 | 2.91 | 2.96 | 0.66 | 23.3 | 7.8 | 1.17 | .284 | 3.44 | 7.65 |
| 3 |  | R. Johnson | 4,356 | 520 | 260 | 136 | .657 | 510 | 3.12 | 96 | 37 | 2 | 3572.1 | 2,807 | 1,239 | 1,401 | 331 | 1,344 | 168 | 5 | 25 | 14,704 | 98 | 10.97 | 3.39 | 3.24 | 0.83 | 29.6 | 9.1 | 1.16 | .291 | 3.53 | 7.07 |
| 4 |  | B. Blyleven | 3,163 | 594 | 249 | 210 | .542 | 590 | 3.37 | 213 | 52 | 0 | 4291.0 | 4,010 | 1,605 | 1,783 | 372 | 1,153 | 141 | 1 | 57 | 17,720 | 101 | 6.63 | 2.42 | 2.74 | 0.78 | 17.8 | 6.5 | 1.20 | .282 | 3.74 | 8.41 |
| 5 |  | G. Maddux | 3,040 | 640 | 317 | 187 | .629 | 636 | 3.01 | 107 | 35 | 0 | 4384.0 | 4,060 | 1,467 | 1,664 | 295 | 905 | 125 | 3 | 161 | 17,834 | 62 | 6.24 | 1.86 | 3.36 | 0.61 | 17.0 | 5.1 | 1.13 | .280 | 3.42 | 8.33 |
| 6 |  | S. Carlton | 2,913 | 516 | 229 | 174 | .568 | 502 | 3.35 | 164 | 31 | 1 | 3659.0 | 3,292 | 1,360 | 1,562 | 311 | 1,307 | 35 | 6 | 104 | 15,234 | 126 | 7.17 | 3.21 | 2.23 | 0.76 | 19.1 | 8.6 | 1.26 | .279 | 3.84 | 8.10 |
| 7 |  | P. Martinez | 2,860 | 418 | 197 | 83 | .704 | 351 | 2.72 | 46 | 17 | 3 | 2508.0 | 1,899 | 757 | 833 | 194 | 660 | 118 | 23 | 22 | 10,009 | 57 | 10.26 | 2.37 | 4.33 | 0.70 | 28.6 | 6.6 | 1.02 | .276 | 2.99 | 6.81 |
| 8 | | C. Schilling | 2,814 | 511 | 190 | 131 | .592 | 378 | 3.40 | 82 | 19 | 22 | 2886.2 | 2,589 | 1,090 | 1,152 | 296 | 657 | 47 | 81 | 41 | 11,733 | 70 | 8.77 | 2.05 | 4.28 | 0.92 | 24.0 | 5.6 | 1.12 | .290 | 3.59 | 8.07 |
| 9 | | F. Tanana | 2,773 | 638 | 240 | 236 | .504 | 616 | 3.66 | 143 | 34 | 1 | 4188.1 | 4,063 | 1,702 | 1,910 | 448 | 1,255 | 129 | 10 | 116 | 17,641 | 119 | 5.96 | 2.70 | 2.21 | 0.96 | 15.7 | 7.1 | 1.27 | .277 | 4.10 | 8.73 |
| 10 | | D. Cone | 2,668 | 450 | 194 | 126 | .606 | 419 | 3.47 | 56 | 22 | 1 | 2898.2 | 2,504 | 1,116 | 1,222 | 258 | 1,137 | 106 | 9 | 42 | 12,184 | 149 | 8.28 | 3.53 | 2.35 | 0.80 | 21.9 | 9.3 | 1.26 | .280 | 3.79 | 7.77 |
| 11 | | C. Finley | 2,610 | 524 | 200 | 173 | .536 | 467 | 3.85 | 63 | 15 | 0 | 3197.1 | 3,069 | 1,366 | 1,517 | 304 | 1,332 | 76 | 24 | 36 | 13,638 | 130 | 7.35 | 3.75 | 1.96 | 0.86 | 19.1 | 9.8 | 1.38 | .297 | 4.27 | 8.64 |
| 12 |  | J. Smoltz | 2,561 | 634 | 177 | 128 | .580 | 393 | 3.25 | 50 | 15 | 154 | 2923.1 | 2,529 | 1,057 | 1,154 | 233 | 880 | 41 | 204 | 67 | 11,970 | 130 | 7.88 | 2.71 | 2.91 | 0.72 | 21.4 | 7.4 | 1.17 | .278 | 3.55 | 7.79 |
| 13 |  | J. Morris | 2,478 | 549 | 254 | 186 | .577 | 527 | 3.90 | 175 | 28 | 0 | 3824.0 | 3,567 | 1,657 | 1,815 | 389 | 1,390 | 58 | 10 | 99 | 16,120 | 205 | 5.83 | 3.27 | 1.78 | 0.92 | 15.4 | 8.6 | 1.30 | .269 | 4.27 | 8.40 |
| 14 | | M. Langston | 2,464 | 457 | 179 | 158 | .531 | 428 | 3.97 | 81 | 18 | 0 | 2962.2 | 2,723 | 1,306 | 1,438 | 311 | 1,289 | 46 | 3 | 34 | 12,562 | 89 | 7.49 | 3.92 | 1.91 | 0.94 | 19.6 | 10.3 | 1.35 | .285 | 4.37 | 8.27 |
| 15 | | D. Eckersley | 2,401 | 1,071 | 197 | 171 | .535 | 361 | 3.50 | 100 | 20 | 390 | 3285.2 | 3,076 | 1,279 | 1,382 | 347 | 738 | 75 | 577 | 90 | 13,534 | 28 | 6.58 | 2.02 | 3.25 | 0.95 | 17.7 | 5.5 | 1.16 | .274 | 3.79 | 8.43 |
| 16 | | K. Brown | 2,397 | 486 | 211 | 144 | .594 | 476 | 3.28 | 72 | 17 | 0 | 3256.1 | 3,079 | 1,185 | 1,357 | 208 | 901 | 139 | 1 | 42 | 13,542 | 108 | 6.62 | 2.49 | 2.66 | 0.57 | 17.7 | 6.7 | 1.22 | .290 | 3.75 | 8.51 |
| 17 | | M. Mussina | 2,393 | 441 | 223 | 127 | .637 | 441 | 3.64 | 56 | 23 | 0 | 3005.1 | 2,863 | 1,214 | 1,290 | 323 | 683 | 42 | 0 | 23 | 12,277 | 63 | 7.17 | 2.05 | 3.50 | 0.97 | 19.5 | 5.6 | 1.18 | .287 | 3.86 | 8.57 |
| 18 | | C. Hough | 2,350 | 846 | 216 | 216 | .500 | 440 | 3.74 | 107 | 13 | 59 | 3780.0 | 3,262 | 1,570 | 1,793 | 375 | 1,650 | 174 | 232 | 44 | 16,070 | 180 | 5.60 | 3.93 | 1.42 | 0.89 | 14.6 | 10.3 | 1.30 | .251 | 4.27 | 7.77 |
| 19 | | T. Glavine | 2,333 | 601 | 273 | 184 | .597 | 601 | 3.45 | 54 | 23 | 0 | 3934.2 | 3,804 | 1,510 | 1,662 | 300 | 1,334 | 55 | 0 | 132 | 16,566 | 62 | 5.34 | 3.05 | 1.75 | 0.69 | 14.1 | 8.1 | 1.31 | .279 | 3.80 | 8.70 |
| 20 | | P. Niekro | 2,323 | 553 | 225 | 191 | .541 | 527 | 3.52 | 158 | 28 | 7 | 3775.1 | 3,590 | 1,475 | 1,688 | 339 | 1,416 | 88 | 17 | 54 | 16,007 | 139 | 5.54 | 3.38 | 1.64 | 0.81 | 14.5 | 8.8 | 1.33 | .275 | 4.02 | 8.56 |
| 21 | | D. Gooden | 2,293 | 430 | 194 | 112 | .634 | 410 | 3.51 | 68 | 24 | 3 | 2800.2 | 2,564 | 1,091 | 1,198 | 210 | 954 | 78 | 4 | 42 | 11,705 | 76 | 7.37 | 3.07 | 2.40 | 0.67 | 19.6 | 8.2 | 1.26 | .288 | 3.85 | 8.24 |
| 22 |  | T. Seaver | 2,286 | 447 | 200 | 140 | .588 | 443 | 3.08 | 131 | 41 | 0 | 3184.1 | 2,692 | 1,089 | 1,197 | 265 | 974 | 44 | 1 | 86 | 12,994 | 90 | 6.46 | 2.75 | 2.35 | 0.75 | 17.6 | 7.5 | 1.15 | .258 | 3.38 | 7.61 |
| 23 | | D. Sutton | 2,254 | 520 | 226 | 162 | .582 | 516 | 3.31 | 107 | 33 | 2 | 3569.2 | 3,184 | 1,311 | 1,446 | 344 | 908 | 49 | 3 | 54 | 14,627 | 70 | 5.68 | 2.29 | 2.48 | 0.87 | 15.4 | 6.2 | 1.15 | .257 | 3.65 | 8.03 |
| 24 | | D. Martinez | 2,149 | 692 | 245 | 193 | .559 | 562 | 3.70 | 122 | 30 | 8 | 3999.2 | 3,897 | 1,643 | 1,835 | 372 | 1,165 | 122 | 51 | 70 | 16,754 | 84 | 4.84 | 2.62 | 1.84 | 0.84 | 12.8 | 7.0 | 1.27 | .272 | 4.13 | 8.77 |
| 25 | | F. Valenzuela | 2,074 | 453 | 173 | 153 | .531 | 424 | 3.54 | 113 | 31 | 2 | 2930.0 | 2,718 | 1,154 | 1,303 | 226 | 1,151 | 25 | 10 | 65 | 12,398 | 119 | 6.37 | 3.54 | 1.80 | 0.69 | 16.7 | 9.3 | 1.32 | .279 | 4.00 | 8.35 |
StatMuse has game-level data for strikeouts going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
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| NL East | W | L | PCT | GB |
|---|---|---|---|---|
 Braves - y | 94 | 68 | .580 | |
 Phillies - w | 88 | 74 | .543 | 6.0 |
80 | 82 | .494 | 14.0 | |
77 | 85 | .475 | 17.0 | |
74 | 88 | .457 | 20.0 | |
| NL Central | W | L | PCT | GB |
 Brewers - y | 103 | 59 | .636 | |
 Cubs - w | 89 | 73 | .549 | 14.0 |
82 | 80 | .506 | 21.0 | |
77 | 85 | .475 | 26.0 | |
75 | 87 | .463 | 28.0 | |
| NL West | W | L | PCT | GB |
 Dodgers - y | 100 | 62 | .617 | |
 Padres - w | 91 | 71 | .562 | 9.0 |
86 | 76 | .531 | 14.0 | |
65 | 97 | .401 | 35.0 | |
58 | 104 | .358 | 42.0 |
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Reds
Diamondbacks
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Rockies| AL East | W | L | PCT | GB |
|---|---|---|---|---|
 Rays - y | 98 | 64 | .605 | |
 Yankees - w | 93 | 68 | .578 | 4.5 |
 Red Sox - w | 87 | 75 | .537 | 11.0 |
79 | 82 | .491 | 18.5 | |
79 | 83 | .488 | 19.0 | |
| AL Central | W | L | PCT | GB |
 Guardians - y | 85 | 77 | .525 | |
 White Sox - w | 84 | 78 | .519 | 1.0 |
77 | 85 | .475 | 8.0 | |
76 | 86 | .469 | 9.0 | |
69 | 93 | .426 | 16.0 | |
| AL West | W | L | PCT | GB |
 Astros - y | 81 | 81 | .500 | |
80 | 82 | .494 | 1.0 | |
76 | 86 | .469 | 5.0 | |
64 | 98 | .395 | 17.0 | |
62 | 100 | .383 | 19.0 |
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Blue Jays
Twins
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