Between July 31, 1996 and September 30, 2017, Randy Johnson fanned the most hitters, with 3,193 strikeouts.
- Regular season
| NAME | SO | G | W | L | W% | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | H/9 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | R. Johnson | 3,193 | 392 | 199 | 102 | .661 | 379 | 3.16 | 59 | 22 | 1 | 2631.0 | 2,187 | 923 | 1,045 | 287 | 721 | 123 | 5 | 28 | 10,697 | 49 | 10.92 | 2.47 | 4.43 | 0.98 | 29.8 | 6.7 | 1.11 | .298 | 3.57 | 7.48 |
| 2 |  | CC Sabathia | 2,846 | 509 | 237 | 146 | .619 | 509 | 3.70 | 38 | 12 | 0 | 3317.0 | 3,142 | 1,364 | 1,487 | 336 | 1,009 | 109 | 0 | 44 | 13,856 | 71 | 7.72 | 2.74 | 2.82 | 0.91 | 20.5 | 7.3 | 1.25 | .294 | 4.03 | 8.53 |
| 3 |  | P. Martinez | 2,562 | 333 | 176 | 73 | .707 | 331 | 2.79 | 40 | 13 | 0 | 2226.0 | 1,734 | 689 | 757 | 188 | 547 | 113 | 1 | 20 | 8,936 | 44 | 10.36 | 2.21 | 4.68 | 0.76 | 28.7 | 6.1 | 1.02 | .280 | 3.06 | 7.01 |
| 4 |  | J. Vazquez | 2,536 | 450 | 165 | 160 | .508 | 443 | 4.22 | 28 | 8 | 0 | 2840.0 | 2,784 | 1,331 | 1,431 | 373 | 763 | 88 | 5 | 58 | 11,935 | 76 | 8.04 | 2.42 | 3.32 | 1.18 | 21.2 | 6.4 | 1.25 | .295 | 4.53 | 8.82 |
| 5 | | A.J. Burnett | 2,513 | 435 | 164 | 157 | .511 | 430 | 3.99 | 24 | 10 | 0 | 2731.1 | 2,519 | 1,210 | 1,328 | 263 | 1,100 | 143 | 1 | 35 | 11,665 | 161 | 8.28 | 3.62 | 2.28 | 0.87 | 21.5 | 9.4 | 1.32 | .295 | 4.38 | 8.30 |
| 6 |  | B. Colon | 2,450 | 536 | 239 | 176 | .576 | 527 | 4.05 | 37 | 13 | 0 | 3309.0 | 3,418 | 1,489 | 1,621 | 406 | 922 | 61 | 1 | 46 | 14,005 | 43 | 6.66 | 2.51 | 2.66 | 1.10 | 17.5 | 6.6 | 1.31 | .296 | 4.41 | 9.30 |
| 7 |  | J. Verlander | 2,416 | 385 | 188 | 114 | .623 | 385 | 3.46 | 23 | 7 | 0 | 2545.0 | 2,242 | 979 | 1,061 | 244 | 771 | 84 | 0 | 27 | 10,513 | 78 | 8.54 | 2.73 | 3.13 | 0.86 | 23.0 | 7.3 | 1.18 | .286 | 3.75 | 7.93 |
| 8 | | C. Schilling | 2,414 | 348 | 169 | 100 | .628 | 326 | 3.42 | 63 | 14 | 9 | 2359.0 | 2,186 | 897 | 929 | 270 | 431 | 37 | 21 | 15 | 9,527 | 48 | 9.21 | 1.64 | 5.60 | 1.03 | 25.3 | 4.5 | 1.11 | .301 | 3.54 | 8.34 |
| 9 |  | F. Hernandez | 2,342 | 375 | 160 | 114 | .584 | 375 | 3.20 | 25 | 11 | 0 | 2502.1 | 2,243 | 890 | 992 | 220 | 721 | 87 | 0 | 16 | 10,274 | 140 | 8.42 | 2.59 | 3.25 | 0.79 | 22.8 | 7.0 | 1.18 | .293 | 3.57 | 8.07 |
| 10 | | J. Lackey | 2,293 | 447 | 188 | 146 | .563 | 446 | 3.92 | 18 | 8 | 0 | 2839.1 | 2,860 | 1,236 | 1,346 | 319 | 815 | 133 | 0 | 32 | 12,025 | 125 | 7.27 | 2.58 | 2.81 | 1.01 | 19.1 | 6.8 | 1.29 | .300 | 4.27 | 9.07 |
| 11 | | A. Pettitte | 2,242 | 477 | 229 | 138 | .624 | 473 | 3.80 | 22 | 4 | 0 | 3002.2 | 3,107 | 1,269 | 1,410 | 258 | 917 | 52 | 1 | 37 | 12,732 | 59 | 6.72 | 2.75 | 2.44 | 0.77 | 17.6 | 7.2 | 1.34 | .308 | 4.23 | 9.31 |
| 12 |  | Z. Greinke | 2,236 | 422 | 172 | 107 | .616 | 381 | 3.40 | 16 | 5 | 1 | 2455.2 | 2,305 | 928 | 1,001 | 243 | 594 | 59 | 8 | 20 | 10,080 | 80 | 8.19 | 2.18 | 3.76 | 0.89 | 22.2 | 5.9 | 1.18 | .297 | 3.67 | 8.45 |
| 13 | | C. Hamels | 2,222 | 362 | 147 | 101 | .593 | 361 | 3.36 | 16 | 7 | 0 | 2359.1 | 2,099 | 881 | 940 | 264 | 644 | 74 | 0 | 42 | 9,663 | 48 | 8.48 | 2.46 | 3.45 | 1.01 | 23.0 | 6.7 | 1.16 | .284 | 3.59 | 8.01 |
| 14 | | J. Peavy | 2,207 | 388 | 152 | 126 | .547 | 377 | 3.63 | 15 | 6 | 0 | 2377.0 | 2,134 | 960 | 1,011 | 259 | 708 | 78 | 3 | 42 | 9,838 | 46 | 8.36 | 2.68 | 3.12 | 0.98 | 22.4 | 7.2 | 1.20 | .285 | 3.83 | 8.08 |
| 15 |  | R. Clemens | 2,175 | 337 | 168 | 76 | .689 | 336 | 3.19 | 22 | 10 | 0 | 2224.1 | 1,895 | 789 | 867 | 173 | 756 | 73 | 0 | 20 | 9,200 | 72 | 8.80 | 3.06 | 2.88 | 0.70 | 23.6 | 8.2 | 1.19 | .286 | 3.51 | 7.67 |
| 16 |  | M. Scherzer | 2,149 | 305 | 141 | 75 | .653 | 296 | 3.30 | 8 | 4 | 0 | 1897.0 | 1,589 | 695 | 751 | 213 | 534 | 66 | 2 | 13 | 7,719 | 61 | 10.20 | 2.53 | 4.02 | 1.01 | 27.8 | 6.9 | 1.12 | .289 | 3.56 | 7.54 |
| 17 | | M. Mussina | 2,135 | 389 | 188 | 115 | .620 | 388 | 3.75 | 32 | 13 | 0 | 2513.2 | 2,475 | 1,048 | 1,129 | 267 | 535 | 50 | 0 | 20 | 10,324 | 53 | 7.64 | 1.92 | 3.99 | 0.96 | 20.7 | 5.2 | 1.20 | .301 | 4.04 | 8.86 |
| 18 |  | C. Kershaw | 2,120 | 292 | 144 | 64 | .692 | 290 | 2.36 | 25 | 15 | 0 | 1935.0 | 1,431 | 508 | 554 | 128 | 507 | 29 | 1 | 27 | 7,602 | 71 | 9.86 | 2.36 | 4.18 | 0.60 | 27.9 | 6.7 | 1.00 | .270 | 2.58 | 6.66 |
| 19 | | R. Halladay | 2,117 | 416 | 203 | 105 | .659 | 390 | 3.38 | 67 | 20 | 1 | 2749.1 | 2,646 | 1,034 | 1,135 | 236 | 592 | 81 | 6 | 28 | 11,287 | 56 | 6.93 | 1.94 | 3.58 | 0.77 | 18.8 | 5.2 | 1.18 | .292 | 3.72 | 8.66 |
| 20 | | K. Millwood | 2,083 | 451 | 169 | 152 | .526 | 443 | 4.11 | 22 | 6 | 0 | 2720.1 | 2,770 | 1,243 | 1,357 | 296 | 843 | 74 | 3 | 46 | 11,616 | 67 | 6.89 | 2.79 | 2.47 | 0.98 | 17.9 | 7.3 | 1.33 | .297 | 4.49 | 9.16 |
| 21 | | J. Shields | 2,080 | 373 | 138 | 123 | .529 | 372 | 3.97 | 23 | 9 | 0 | 2411.1 | 2,391 | 1,064 | 1,152 | 327 | 668 | 88 | 0 | 22 | 10,122 | 96 | 7.76 | 2.49 | 3.11 | 1.22 | 20.5 | 6.6 | 1.27 | .297 | 4.30 | 8.92 |
| 22 | | T. Hudson | 2,080 | 482 | 222 | 133 | .625 | 479 | 3.49 | 26 | 13 | 0 | 3126.2 | 2,957 | 1,213 | 1,319 | 248 | 917 | 124 | 0 | 84 | 13,005 | 84 | 5.99 | 2.64 | 2.27 | 0.71 | 16.0 | 7.1 | 1.24 | .281 | 3.80 | 8.51 |
| 23 | | R. Dempster | 2,075 | 579 | 132 | 133 | .498 | 351 | 4.35 | 11 | 3 | 87 | 2387.0 | 2,347 | 1,154 | 1,250 | 267 | 1,071 | 91 | 186 | 47 | 10,412 | 80 | 7.82 | 4.04 | 1.94 | 1.01 | 19.9 | 10.3 | 1.43 | .301 | 4.71 | 8.85 |
| 24 |  | J. Lester | 2,041 | 349 | 159 | 92 | .633 | 348 | 3.51 | 15 | 4 | 0 | 2184.1 | 2,008 | 853 | 920 | 208 | 704 | 73 | 0 | 7 | 9,070 | 54 | 8.41 | 2.90 | 2.90 | 0.86 | 22.5 | 7.8 | 1.24 | .298 | 3.79 | 8.27 |
| 25 | | D. Haren | 2,013 | 391 | 153 | 131 | .539 | 380 | 3.75 | 16 | 6 | 1 | 2419.2 | 2,357 | 1,009 | 1,105 | 305 | 500 | 67 | 4 | 39 | 10,022 | 98 | 7.49 | 1.86 | 4.03 | 1.13 | 20.1 | 5.0 | 1.18 | .288 | 4.11 | 8.77 |
StatMuse has game-level data for strikeouts going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
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