Before April 1, 2011, Reggie Jackson had the most strikeouts, with 2,596 strikeouts.

Interpreted as:

most strikeouts by a player through march 31, 2011

	NAME	SO	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Reggie Jackson R. Jackson	2,596	2,820	9,864	1,551	2,584	463	49	563	1,702	1,376	96	228	115	11,417	4,834	1,075	13	68	164	183	.262	.356	.490	.846
2	Jim Thome J. Thome	2,395	2,392	7,982	1,534	2,216	428	26	589	1,624	1,679	68	19	20	9,803	4,463	1,043	1	73	166	153	.278	.404	.559	.963
3	Sammy Sosa S. Sosa	2,306	2,354	8,813	1,475	2,408	379	45	609	1,667	929	59	234	107	9,896	4,704	1,033	17	78	154	202	.273	.344	.534	.878
4	Andres Galarraga A. Galarraga	2,003	2,257	8,096	1,195	2,333	444	32	399	1,425	583	178	128	81	8,916	4,038	875	1	58	106	178	.288	.347	.499	.846
5	Jose Canseco J. Canseco	1,942	1,887	7,057	1,186	1,877	340	14	462	1,407	906	84	200	88	8,129	3,631	816	1	81	64	178	.266	.353	.515	.867
6	Willie Stargell W. Stargell	1,936	2,360	7,927	1,195	2,232	423	55	475	1,540	937	79	17	16	9,027	4,190	953	9	75	227	144	.282	.360	.529	.889
7	Mike Schmidt M. Schmidt	1,883	2,404	8,352	1,506	2,234	408	59	548	1,595	1,507	79	174	91	10,062	4,404	1,015	16	108	201	156	.267	.380	.527	.908
8	Fred McGriff F. McGriff	1,882	2,460	8,757	1,349	2,490	441	24	493	1,550	1,305	39	72	38	10,174	4,458	958	2	71	171	226	.284	.377	.509	.886
9	Tony Perez T. Perez	1,867	2,777	9,778	1,272	2,732	505	79	379	1,652	925	43	49	33	10,861	4,532	963	9	106	150	264	.279	.341	.463	.804
10	Mike Cameron M. Cameron	1,842	1,877	6,602	1,037	1,652	373	59	269	941	839	87	296	83	7,615	2,950	701	29	58	19	108	.250	.340	.447	.787
11	Alex Rodriguez A. Rodriguez	1,836	2,304	8,828	1,758	2,673	475	29	613	1,831	1,121	152	301	72	10,210	5,045	1,117	16	93	87	209	.303	.387	.571	.959
12	Dave Kingman D. Kingman	1,816	1,941	6,677	901	1,575	240	25	442	1,210	608	53	85	49	7,429	3,191	707	16	75	72	139	.236	.302	.478	.780
13	Manny Ramirez M. Ramirez	1,809	2,297	8,227	1,544	2,573	547	20	555	1,830	1,329	109	38	33	9,757	4,825	1,122	2	90	216	243	.313	.411	.586	.998
14	Ken Griffey Jr. K. Griffey Jr.	1,779	2,671	9,801	1,662	2,781	524	38	630	1,836	1,312	81	184	69	11,304	5,271	1,192	8	102	246	199	.284	.370	.538	.907
15	Bobby Bonds B. Bonds	1,757	1,849	7,043	1,258	1,886	302	66	332	1,024	914	53	461	169	8,090	3,316	700	16	64	75	105	.268	.353	.471	.824
16	Craig Biggio C. Biggio	1,753	2,850	10,876	1,844	3,060	668	55	291	1,175	1,160	285	414	124	12,503	4,711	1,014	101	81	68	150	.281	.363	.433	.796
17	Dale Murphy D. Murphy	1,748	2,180	7,960	1,197	2,111	350	39	398	1,266	986	28	161	68	9,040	3,733	787	6	60	159	209	.265	.346	.469	.815
18	Carlos Delgado C. Delgado	1,745	2,035	7,283	1,241	2,038	483	18	473	1,512	1,109	172	14	8	8,657	3,976	974	0	93	186	152	.280	.383	.546	.929
19	Lou Brock L. Brock	1,730	2,616	10,332	1,610	3,023	486	141	149	900	761	49	938	306	11,235	4,238	776	47	46	124	115	.293	.343	.410	.753
20	Jim Edmonds J. Edmonds	1,729	2,011	6,858	1,251	1,949	437	25	393	1,199	998	49	67	50	7,980	3,615	855	10	65	91	122	.284	.376	.527	.903
21	Mickey Mantle M. Mantle	1,718	2,401	8,101	1,675	2,415	344	72	536	1,509	1,733	12	152	42	9,907	4,511	952	14	47	126	113	.298	.420	.557	.977
22	Harmon Killebrew H. Killebrew	1,704	2,435	8,147	1,282	2,086	290	24	573	1,583	1,561	48	19	20	9,833	4,143	887	0	77	161	243	.256	.376	.509	.884
23	Chili Davis C. Davis	1,698	2,435	8,673	1,240	2,380	424	30	350	1,372	1,194	15	142	98	9,996	3,914	804	20	94	188	232	.274	.360	.451	.811
24	Dwight Evans D. Evans	1,697	2,606	8,996	1,470	2,446	483	73	385	1,384	1,391	53	78	59	10,569	4,230	941	52	77	60	227	.272	.370	.470	.840
25	Rickey Henderson R. Henderson	1,694	3,081	10,961	2,295	3,055	510	66	297	1,115	2,190	98	1,406	335	13,346	4,588	873	30	67	61	172	.279	.401	.419	.820