Between the 1910 and 1919 seasons, Walter Johnson won the most games, with 265 wins.

Interpreted as:

most regular-season wins by a pitcher in the 1910's

	NAME	W	L	W%	G	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Walter Johnson W. Johnson	265	143	.650	454	361	1.59	2,219	327	74	20	3427.2	2,604	606	881	29	661	114	88	13,100	100	5.83	1.74	3.36	0.08	16.9	5.0	0.95	.256	2.31	56	1.96	67	6.84	357.8
2	Grover Alexander G. Alexander	208	100	.675	362	307	2.09	1,539	242	70	16	2753.0	2,300	638	846	49	596	55	50	10,891	20	5.03	1.95	2.58	0.16	14.1	5.5	1.05	.260	2.77	68	2.32	75	7.52	234.9
3	Eddie Cicotte E. Cicotte	162	120	.574	396	284	2.29	1,104	193	28	19	2535.0	2,241	645	885	23	633	38	81	9,959	37	3.92	2.25	1.74	0.08	11.1	6.4	1.13	.272	3.14	80	2.49	86	7.96	115.3
4	Hippo Vaughn H. Vaughn	156	110	.586	331	280	2.31	1,253	183	37	5	2317.1	2,006	595	835	23	701	72	40	9,460	59	4.87	2.72	1.79	0.09	13.2	7.4	1.17	.268	3.24	79	2.46	85	7.79	110.8
5	Slim Sallee S. Sallee	149	114	.567	356	252	2.47	704	163	23	32	2244.2	2,102	615	808	53	448	33	85	9,048	9	2.82	1.80	1.57	0.21	7.8	5.0	1.14	.262	3.24	84	2.82	95	8.43	35
6	Rube Marquard R. Marquard	144	103	.583	330	255	2.71	1,141	142	24	17	2128.1	1,942	641	816	62	527	18	49	8,621	56	4.82	2.23	2.17	0.26	13.2	6.1	1.16	.274	3.45	93	2.57	87	8.21	95.3
7	Eddie Plank E. Plank	140	73	.657	289	215	2.25	904	147	33	22	1829.2	1,598	458	611	16	473	50	61	7,158	31	4.45	2.33	1.91	0.08	12.6	6.6	1.13	.277	3.01	79	2.49	87	7.86	74.9
8	Christy Mathewson C. Mathewson	137	76	.643	247	207	2.39	708	153	18	14	1814.0	1,784	481	668	52	204	9	34	7,226	25	3.51	1.01	3.47	0.26	9.8	2.8	1.10	.277	3.31	81	2.50	82	8.85	114.1
9	Claude Hendrix C. Hendrix	135	104	.565	333	234	2.56	1,020	172	27	17	2167.2	1,907	617	809	35	643	46	80	8,779	66	4.23	2.67	1.59	0.15	11.6	7.3	1.18	.266	3.36	86	2.70	92	7.92	52.6
10	Hooks Dauss H. Dauss	126	92	.578	269	219	2.85	739	156	16	15	1869.0	1,714	592	781	25	591	82	43	7,558	42	3.56	2.85	1.25	0.12	9.8	7.8	1.23	.276	3.76	98	2.85	96	8.25	24.3
11	Jack Coombs J. Coombs	123	75	.621	250	191	2.91	711	136	22	5	1650.0	1,488	534	671	34	570	63	49	6,742	32	3.88	3.11	1.25	0.19	10.5	8.5	1.25	.271	3.66	100	3.05	108	8.12	-45
12	Jeff Tesreau J. Tesreau	119	72	.623	247	207	2.43	880	123	27	9	1679.0	1,350	453	591	37	572	38	25	6,805	42	4.72	3.07	1.54	0.20	12.9	8.4	1.14	.249	3.17	89	2.79	99	7.24	2.5
13	Babe Adams B. Adams	119	89	.572	278	231	2.50	714	140	27	4	1908.2	1,711	531	667	34	298	32	37	7,517	16	3.37	1.41	2.40	0.16	9.5	4.0	1.05	.260	3.15	85	2.53	84	8.07	105.2
14	Larry Cheney L. Cheney	116	100	.537	313	225	2.70	926	132	20	19	1881.1	1,605	564	784	36	733	59	63	7,865	119	4.43	3.51	1.26	0.17	11.8	9.3	1.24	.257	3.75	92	3.00	101	7.68	-5.6
15	Dick Rudolph D. Rudolph	116	97	.545	253	222	2.56	756	167	26	8	1923.1	1,817	548	699	29	362	22	30	7,719	36	3.54	1.69	2.09	0.14	9.8	4.7	1.13	.273	3.27	92	2.40	86	8.50	87
16	Lefty Tyler L. Tyler	113	102	.526	286	234	2.90	938	159	28	7	1987.0	1,738	641	842	43	758	64	41	8,203	52	4.25	3.43	1.24	0.19	11.4	9.2	1.26	.265	3.81	95	3.05	100	7.87	3.3
17	Bob Groom B. Groom	112	124	.475	323	257	3.13	1,028	140	21	13	2075.2	1,987	723	954	47	678	42	38	8,431	49	4.46	2.94	1.52	0.20	12.2	8.0	1.28	.292	4.14	106	2.85	98	8.62	19.7
18	Red Ames R. Ames	111	117	.487	359	232	2.73	858	118	18	29	2011.1	1,914	611	838	30	574	40	90	8,274	78	3.84	2.57	1.49	0.13	10.4	6.9	1.24	.278	3.75	94	2.71	92	8.56	53.9
19	Chief Bender C. Bender	110	56	.663	237	161	2.47	776	108	19	26	1467.0	1,335	402	517	19	349	43	66	5,772	41	4.76	2.14	2.22	0.12	13.4	6.0	1.15	.287	3.17	85	2.42	85	8.19	71.1
20	Ray Caldwell R. Caldwell	108	104	.509	272	214	3.00	850	160	19	4	1857.1	1,644	620	746	43	626	57	47	7,437	25	4.12	3.03	1.36	0.21	11.4	8.4	1.22	.273	3.61	99	2.97	98	7.97	15
21	Rube Benton R. Benton	106	97	.522	288	216	2.98	750	103	16	16	1723.2	1,587	570	741	27	549	82	54	7,164	52	3.92	2.87	1.37	0.14	10.5	7.7	1.24	.271	3.87	104	2.92	100	8.29	0
22	Joe Wood J. Wood	105	49	.682	194	137	1.97	889	107	23	10	1249.0	999	274	429	9	360	42	49	4,896	38	6.41	2.59	2.47	0.06	18.2	7.4	1.09	.275	3.09	66	2.25	76	7.20	103.1
23	Dutch Leonard D. Leonard	104	77	.575	240	189	2.22	873	114	29	11	1578.2	1,346	389	514	23	477	48	41	6,283	36	4.98	2.72	1.83	0.13	13.9	7.6	1.15	.272	2.93	80	2.47	87	7.67	58.7
24	Bob Harmon B. Harmon	101	122	.453	300	223	3.31	586	133	15	12	1895.0	1,811	696	872	38	697	34	58	7,871	32	2.78	3.31	0.84	0.18	7.4	8.9	1.32	.272	4.14	109	3.33	108	8.60	-57.7
25	Russ Ford R. Ford	99	71	.582	198	170	2.58	708	126	15	9	1484.1	1,336	425	591	45	372	31	27	5,892	19	4.29	2.26	1.90	0.27	12.0	6.3	1.15	.273	3.58	81	2.83	91	8.10	47.4