Between the 2003 and 2008 seasons, Johan Santana won the most games by a starting pitcher, with 97 wins.
| NAME | W | L | W% | G | GS | ERA | SO | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | H/9 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | J. Santana | 97 | 41 | .703 | 186 | 186 | 2.82 | 1,298 | 9 | 6 | 0 | 1257.0 | 994 | 394 | 425 | 140 | 288 | 23 | 0 | 6 | 4,990 | 39 | 9.29 | 2.06 | 4.51 | 1.00 | 26.0 | 5.8 | 1.02 | .263 | 3.04 | 7.12 |
| 2 | | R. Oswalt | 95 | 51 | .651 | 187 | 187 | 3.20 | 980 | 12 | 5 | 0 | 1245.0 | 1,230 | 442 | 477 | 104 | 284 | 47 | 0 | 20 | 5,159 | 14 | 7.08 | 2.05 | 3.45 | 0.75 | 19.0 | 5.5 | 1.22 | .301 | 3.45 | 8.89 |
| 3 | | R. Halladay | 94 | 42 | .691 | 172 | 172 | 3.24 | 882 | 35 | 8 | 0 | 1229.2 | 1,170 | 443 | 487 | 102 | 210 | 37 | 0 | 15 | 4,968 | 21 | 6.46 | 1.54 | 4.20 | 0.75 | 17.8 | 4.2 | 1.12 | .286 | 3.56 | 8.56 |
| 4 | | C. Zambrano | 91 | 51 | .641 | 193 | 193 | 3.39 | 1,075 | 8 | 3 | 0 | 1266.0 | 1,053 | 477 | 525 | 105 | 549 | 67 | 0 | 28 | 5,341 | 35 | 7.64 | 3.90 | 1.96 | 0.75 | 20.1 | 10.3 | 1.27 | .267 | 3.73 | 7.49 |
| 5 | | M. Mussina | 88 | 51 | .633 | 181 | 181 | 3.99 | 881 | 6 | 3 | 0 | 1105.0 | 1,148 | 490 | 531 | 119 | 228 | 29 | 0 | 11 | 4,580 | 19 | 7.18 | 1.86 | 3.86 | 0.97 | 19.2 | 5.0 | 1.25 | .310 | 4.32 | 9.35 |
| 6 | | B. Webb | 87 | 62 | .584 | 197 | 197 | 3.24 | 1,062 | 15 | 8 | 0 | 1314.2 | 1,194 | 473 | 551 | 90 | 432 | 49 | 0 | 34 | 5,491 | 56 | 7.27 | 2.96 | 2.46 | 0.62 | 19.3 | 7.9 | 1.24 | .286 | 3.77 | 8.17 |
| 7 | | A. Pettitte | 87 | 56 | .608 | 183 | 183 | 3.83 | 905 | 3 | 1 | 0 | 1144.1 | 1,194 | 487 | 543 | 108 | 314 | 14 | 0 | 19 | 4,832 | 22 | 7.12 | 2.47 | 2.88 | 0.85 | 18.7 | 6.5 | 1.32 | .311 | 4.27 | 9.39 |
| 8 |  | CC Sabathia | 87 | 57 | .604 | 188 | 188 | 3.43 | 1,073 | 24 | 10 | 0 | 1269.0 | 1,194 | 484 | 529 | 114 | 340 | 42 | 0 | 12 | 5,242 | 18 | 7.61 | 2.41 | 3.16 | 0.81 | 20.5 | 6.5 | 1.21 | .294 | 3.75 | 8.47 |
| 9 | | J. Garland | 84 | 62 | .575 | 193 | 193 | 4.39 | 635 | 8 | 5 | 0 | 1245.1 | 1,320 | 608 | 660 | 156 | 353 | 33 | 0 | 17 | 5,275 | 22 | 4.59 | 2.55 | 1.80 | 1.13 | 12.0 | 6.7 | 1.34 | .284 | 4.77 | 9.54 |
| 10 | | D. Lowe | 84 | 67 | .556 | 201 | 201 | 4.02 | 775 | 8 | 2 | 0 | 1232.1 | 1,271 | 550 | 645 | 108 | 357 | 31 | 0 | 18 | 5,241 | 17 | 5.66 | 2.61 | 2.17 | 0.79 | 14.8 | 6.8 | 1.32 | .293 | 4.71 | 9.28 |
| 11 | | M. Buehrle | 83 | 66 | .557 | 199 | 199 | 3.91 | 786 | 14 | 3 | 0 | 1336.0 | 1,442 | 580 | 658 | 155 | 297 | 33 | 0 | 22 | 5,594 | 8 | 5.29 | 2.00 | 2.65 | 1.04 | 14.1 | 5.3 | 1.30 | .298 | 4.43 | 9.71 |
| 12 | | J. Moyer | 82 | 59 | .582 | 197 | 197 | 4.28 | 720 | 6 | 1 | 0 | 1221.0 | 1,287 | 581 | 620 | 168 | 356 | 48 | 0 | 18 | 5,240 | 12 | 5.31 | 2.62 | 2.02 | 1.24 | 13.7 | 6.8 | 1.35 | .283 | 4.57 | 9.49 |
| 13 | | T. Hudson | 82 | 51 | .617 | 181 | 181 | 3.53 | 738 | 12 | 7 | 0 | 1204.1 | 1,166 | 472 | 514 | 89 | 342 | 50 | 0 | 40 | 5,031 | 29 | 5.52 | 2.56 | 2.16 | 0.67 | 14.7 | 6.8 | 1.25 | .283 | 3.84 | 8.71 |
| 14 |  | G. Maddux | 82 | 75 | .522 | 205 | 205 | 4.13 | 730 | 7 | 1 | 0 | 1258.0 | 1,326 | 577 | 633 | 143 | 194 | 36 | 0 | 30 | 5,205 | 20 | 5.22 | 1.39 | 3.76 | 1.02 | 14.0 | 3.7 | 1.21 | .288 | 4.53 | 9.49 |
| 15 | | J. Lackey | 82 | 59 | .582 | 188 | 188 | 3.83 | 992 | 12 | 7 | 0 | 1215.1 | 1,228 | 517 | 566 | 124 | 361 | 60 | 0 | 18 | 5,155 | 70 | 7.35 | 2.67 | 2.75 | 0.92 | 19.2 | 7.0 | 1.31 | .305 | 4.19 | 9.09 |
| 16 | | T. Lilly | 81 | 61 | .570 | 188 | 188 | 4.28 | 928 | 2 | 1 | 0 | 1094.1 | 1,031 | 521 | 548 | 161 | 405 | 28 | 0 | 16 | 4,685 | 31 | 7.63 | 3.33 | 2.29 | 1.32 | 19.8 | 8.6 | 1.31 | .275 | 4.51 | 8.48 |
| 17 | | J. Beckett | 81 | 53 | .604 | 168 | 168 | 3.80 | 993 | 5 | 2 | 0 | 1056.0 | 974 | 446 | 477 | 110 | 316 | 39 | 0 | 11 | 4,395 | 35 | 8.46 | 2.69 | 3.14 | 0.94 | 22.6 | 7.2 | 1.22 | .294 | 4.07 | 8.30 |
| 18 | | J. Peavy | 80 | 55 | .593 | 182 | 182 | 3.14 | 1,166 | 6 | 3 | 0 | 1163.1 | 983 | 406 | 430 | 117 | 374 | 41 | 0 | 27 | 4,786 | 20 | 9.02 | 2.89 | 3.12 | 0.91 | 24.4 | 7.8 | 1.17 | .280 | 3.33 | 7.60 |
| 19 | | J. Suppan | 79 | 59 | .572 | 191 | 191 | 4.28 | 640 | 4 | 2 | 0 | 1157.0 | 1,270 | 550 | 612 | 141 | 380 | 46 | 0 | 30 | 5,040 | 35 | 4.98 | 2.96 | 1.68 | 1.10 | 12.7 | 7.5 | 1.43 | .295 | 4.76 | 9.88 |
| 20 | | L. Hernandez | 78 | 70 | .527 | 201 | 201 | 4.33 | 796 | 22 | 2 | 0 | 1335.0 | 1,477 | 643 | 683 | 166 | 424 | 45 | 0 | 37 | 5,768 | 17 | 5.37 | 2.86 | 1.88 | 1.12 | 13.8 | 7.4 | 1.42 | .302 | 4.60 | 9.96 |
| 21 | | C. Lee | 76 | 38 | .667 | 154 | 154 | 4.17 | 707 | 7 | 2 | 0 | 949.0 | 966 | 440 | 484 | 116 | 280 | 33 | 0 | 8 | 4,041 | 25 | 6.70 | 2.66 | 2.53 | 1.10 | 17.5 | 6.9 | 1.31 | .293 | 4.59 | 9.16 |
| 22 | | J. Vazquez | 76 | 73 | .510 | 196 | 196 | 4.28 | 1,178 | 11 | 2 | 0 | 1270.1 | 1,232 | 604 | 643 | 173 | 328 | 47 | 0 | 17 | 5,326 | 43 | 8.35 | 2.32 | 3.59 | 1.23 | 22.1 | 6.2 | 1.23 | .294 | 4.56 | 8.73 |
| 23 | | B. Zito | 76 | 76 | .500 | 203 | 203 | 4.15 | 882 | 4 | 1 | 0 | 1269.2 | 1,166 | 585 | 639 | 140 | 542 | 49 | 0 | 24 | 5,446 | 24 | 6.25 | 3.84 | 1.63 | 0.99 | 16.2 | 10.0 | 1.35 | .268 | 4.53 | 8.27 |
| 24 | | K. Rogers | 74 | 49 | .602 | 170 | 170 | 4.43 | 545 | 3 | 2 | 0 | 1039.0 | 1,146 | 511 | 559 | 114 | 324 | 46 | 0 | 11 | 4,499 | 18 | 4.72 | 2.81 | 1.68 | 0.99 | 12.1 | 7.2 | 1.41 | .297 | 4.84 | 9.93 |
| 25 | | T. Wakefield | 73 | 63 | .537 | 180 | 180 | 4.44 | 750 | 5 | 0 | 0 | 1120.0 | 1,074 | 553 | 611 | 153 | 376 | 66 | 0 | 8 | 4,784 | 53 | 6.03 | 3.02 | 1.99 | 1.23 | 15.7 | 7.9 | 1.29 | .268 | 4.91 | 8.63 |
StatMuse has game-level data for pitcher wins going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
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