Jake Peavy has fanned the most career hitters for the Padres, with 1,348 strikeouts.

	NAME	SO	G	W	L	W%	GS	ERA	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Jake Peavy J. Peavy	1,348	212	92	68	.575	212	3.29	7	3	0	1342.2	1,158	491	522	135	435	45	0	31	5,551	26	9.04	2.92	3.10	0.90	24.3	7.8	1.19	.285	3.50	83	3.46	83	7.76	112
2	Andy Benes A. Benes	1,036	187	69	75	.479	186	3.57	15	8	0	1235.0	1,128	490	539	115	402	20	1	30	5,163	27	7.55	2.93	2.58	0.84	20.1	7.8	1.24	.282	3.93	93	3.47	88	8.22	67.1
3	Trevor Hoffman T. Hoffman	1,029	902	54	64	.458	0	2.76	0	0	552	952.1	738	292	323	85	255	8	761	46	3,821	42	9.72	2.41	4.04	0.80	26.9	6.7	1.04	.267	3.05	68	2.92	69	6.97	142.7
4	Eric Show E. Show	951	309	100	87	.535	230	3.59	35	11	7	1603.1	1,464	639	703	166	593	46	31	48	6,737	34	5.34	3.33	1.60	0.93	14.1	8.8	1.28	.261	3.95	100	4.11	110	8.22	-68.1
5	Andy Ashby A. Ashby	829	187	70	62	.530	185	3.59	18	6	0	1212.0	1,186	484	553	130	324	37	2	31	5,053	35	6.16	2.41	2.56	0.97	16.4	6.4	1.25	.283	4.11	89	4.03	95	8.81	29.2
6	Clay Kirby C. Kirby	802	177	52	81	.391	170	3.73	34	7	0	1128.0	1,026	468	534	118	505	21	4	50	4,832	48	6.40	4.03	1.59	0.94	16.6	10.5	1.36	.268	4.26	107	3.84	113	8.19	-63.8
7	Ed Whitson E. Whitson	767	227	77	72	.517	208	3.69	22	6	1	1354.1	1,314	555	596	148	350	14	4	23	5,600	15	5.10	2.33	2.19	0.98	13.7	6.3	1.23	.270	3.96	101	3.88	103	8.73	-15.8
8	Yu Darvish Y. Darvish	683	115	44	37	.543	115	3.97	0	0	0	651.0	551	287	295	94	165	37	0	1	2,653	20	9.44	2.28	4.14	1.30	25.7	6.2	1.10	.273	4.08	100	3.87	94	7.62	17.7
9	Clayton Richard C. Richard	678	178	58	68	.460	175	4.37	4	3	0	1046.1	1,120	508	559	122	356	30	1	20	4,487	29	5.83	3.06	1.90	1.05	15.1	7.9	1.41	.302	4.81	115	4.43	113	9.63	-57.6
10	Randy Jones R. Jones	677	264	92	105	.467	253	3.30	71	18	2	1766.0	1,720	648	759	110	414	13	7	84	7,292	16	3.45	2.11	1.64	0.56	9.3	5.7	1.21	.265	3.87	96	3.40	97	8.77	19.2
11	Joey Hamilton J. Hamilton	639	146	55	44	.556	142	3.83	7	4	0	934.2	912	398	442	80	343	46	2	23	3,994	33	6.15	3.30	1.86	0.77	16.0	8.6	1.34	.288	4.26	96	4.12	98	8.78	9.5
12	Tyson Ross T. Ross	638	122	32	44	.421	103	3.40	3	1	0	645.1	558	244	276	46	253	33	8	12	2,695	38	8.90	3.53	2.52	0.64	23.7	9.4	1.26	.297	3.85	93	3.40	90	7.78	26.7
13	Adam Eaton A. Eaton	623	133	47	41	.534	131	4.34	3	0	0	796.0	787	384	418	101	282	31	2	21	3,429	25	7.04	3.19	2.21	1.14	18.2	8.2	1.34	.287	4.73	108	4.31	102	8.90	-8.8
14	Bruce Hurst B. Hurst	616	131	55	38	.591	131	3.27	29	10	0	911.2	835	331	361	76	242	4	0	18	3,730	24	6.08	2.39	2.55	0.75	16.5	6.5	1.18	.272	3.56	90	3.34	89	8.24	41.2
15	Joe Musgrove J. Musgrove	585	98	37	24	.607	97	3.20	2	2	0	559.1	480	199	214	68	140	51	1	5	2,297	9	9.41	2.25	4.18	1.09	25.5	6.1	1.11	.284	3.44	81	3.67	90	7.72	27.1
16	Brian Lawrence B. Lawrence	579	162	49	61	.445	146	4.10	7	3	0	934.0	980	426	463	97	255	45	5	33	3,984	12	5.58	2.46	2.27	0.93	14.5	6.4	1.32	.294	4.46	105	4.08	99	9.44	3.6
17	Blake Snell B. Snell	575	83	29	25	.537	83	3.15	0	0	0	436.2	319	153	159	42	219	8	0	1	1,827	26	11.85	4.51	2.63	0.87	31.5	12.0	1.23	.282	3.28	79	3.36	80	6.57	40
18	Sterling Hitchcock S. Hitchcock	548	122	34	42	.447	106	4.47	4	1	1	649.0	656	322	346	100	216	24	4	11	2,796	38	7.60	3.00	2.54	1.39	19.6	7.7	1.34	.291	4.80	110	4.54	106	9.10	-19.6
19	Woody Williams W. Williams	528	132	51	45	.531	131	4.32	4	0	0	826.1	861	397	428	129	250	20	0	15	3,540	22	5.75	2.72	2.11	1.41	14.9	7.1	1.34	.280	4.66	105	4.82	112	9.38	-48.8
20	Andrew Cashner A. Cashner	505	130	28	43	.394	97	3.67	3	3	0	608.2	583	248	291	56	191	18	7	9	2,560	13	7.47	2.82	2.64	0.83	19.7	7.5	1.27	.294	4.30	100	3.67	97	8.62	6.3
21	Chris Young C. Young	489	97	33	25	.569	97	3.60	1	0	0	550.2	416	220	233	64	240	16	0	11	2,292	18	7.99	3.92	2.04	1.05	21.3	10.5	1.19	.237	3.81	90	4.28	101	6.80	-3.3
22	Andy Hawkins A. Hawkins	489	199	60	58	.508	172	3.84	19	7	0	1102.2	1,089	471	531	99	412	26	14	30	4,712	19	3.99	3.36	1.19	0.81	10.4	8.7	1.36	.269	4.33	108	4.22	114	8.89	-61.6
23	Greg Harris G. Harris	462	194	41	39	.513	71	2.95	9	2	15	673.1	591	221	250	61	205	12	60	36	2,782	11	6.18	2.74	2.25	0.82	16.6	7.4	1.18	.260	3.34	79	3.61	94	7.90	16.5
24	Dave Dravecky D. Dravecky	456	199	53	50	.515	119	3.12	23	6	10	900.1	812	312	354	83	270	13	37	23	3,701	8	4.56	2.70	1.69	0.83	12.3	7.3	1.20	.253	3.54	87	3.87	104	8.12	-14.8
25	Tim Lollar T. Lollar	454	119	36	42	.462	106	4.07	8	4	1	680.2	617	308	325	64	328	12	4	15	2,917	30	6.00	4.34	1.38	0.85	15.6	11.2	1.39	.269	4.30	118	4.11	115	8.16	-40.3