Since 1937, Randy Johnson and Nolan Ryan are tied for playing the most seasons with 310+ strikeouts, with 5 seasons.
| NAME | SEAS | SO | G | W | L | W% | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | ERA- | FIP | FIP- | H/9 | PRAA | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | R. Johnson | 5 | 1,746 | 174 | 100 | 38 | .725 | 173 | 2.63 | 41 | 17 | 0 | 1274.1 | 990 | 373 | 429 | 121 | 374 | 60 | 1 | 8 | 5,123 | 27 | 12.33 | 2.64 | 4.67 | 0.85 | 34.1 | 7.3 | 1.07 | .308 | 3.03 | 58 | 2.59 | 57 | 6.99 | 271.4 |
| 2 |  | N. Ryan | 5 | 1,747 | 198 | 98 | 82 | .544 | 195 | 2.84 | 115 | 27 | 1 | 1526.0 | 1,016 | 481 | 547 | 75 | 908 | 40 | 3 | 18 | 6,369 | 68 | 10.30 | 5.36 | 1.92 | 0.44 | 27.4 | 14.3 | 1.26 | .261 | 3.23 | 83 | 2.79 | 80 | 5.99 | 122.2 |
| 3 |  | C. Schilling | 2 | 635 | 71 | 40 | 18 | .690 | 70 | 3.10 | 12 | 3 | 0 | 513.2 | 426 | 177 | 191 | 54 | 91 | 8 | 0 | 4 | 2,026 | 11 | 11.13 | 1.59 | 6.98 | 0.95 | 31.3 | 4.5 | 1.01 | .300 | 3.35 | 72 | 2.50 | 58 | 7.46 | 100.2 |
| 4 |  | S. Koufax | 2 | 699 | 84 | 53 | 17 | .757 | 82 | 1.89 | 54 | 13 | 2 | 658.2 | 457 | 138 | 164 | 45 | 148 | 5 | 2 | 8 | 2,571 | 18 | 9.55 | 2.02 | 4.72 | 0.61 | 27.2 | 5.8 | 0.92 | .246 | 2.24 | 58 | 2.00 | 63 | 6.24 | 89.7 |
| 5 |  | G. Cole | 1 | 326 | 33 | 20 | 5 | .800 | 33 | 2.50 | 0 | 0 | 0 | 212.1 | 142 | 59 | 66 | 29 | 48 | 3 | 0 | 0 | 817 | 4 | 13.82 | 2.03 | 6.79 | 1.23 | 39.9 | 5.9 | 0.89 | .275 | 2.80 | 55 | 2.63 | 58 | 6.02 | 45 |
| 6 |  | P. Martinez | 1 | 313 | 31 | 23 | 4 | .852 | 29 | 2.07 | 5 | 1 | 0 | 213.1 | 160 | 49 | 56 | 9 | 37 | 9 | 1 | 1 | 835 | 6 | 13.20 | 1.56 | 8.46 | 0.38 | 37.5 | 4.4 | 0.92 | .323 | 2.36 | 42 | 1.38 | 30 | 6.75 | 79.4 |
| 7 | | J.R. Richard | 1 | 313 | 38 | 18 | 13 | .581 | 38 | 2.71 | 19 | 4 | 0 | 292.1 | 220 | 88 | 98 | 13 | 98 | 3 | 0 | 5 | 1,175 | 19 | 9.64 | 3.02 | 3.19 | 0.40 | 26.6 | 8.3 | 1.09 | .277 | 3.02 | 78 | 2.19 | 62 | 6.77 | 45.6 |
| 8 |  | S. Carlton | 1 | 310 | 41 | 27 | 10 | .730 | 41 | 1.97 | 30 | 8 | 0 | 346.1 | 257 | 76 | 84 | 17 | 87 | 1 | 0 | 8 | 1,351 | 8 | 8.06 | 2.26 | 3.56 | 0.44 | 22.9 | 6.4 | 0.99 | .256 | 2.18 | 56 | 2.00 | 59 | 6.68 | 53.5 |
| 9 | | S. McDowell | 1 | 325 | 42 | 17 | 11 | .607 | 35 | 2.18 | 14 | 3 | 4 | 273.0 | 178 | 66 | 80 | 9 | 132 | 6 | 5 | 7 | 1,116 | 17 | 10.71 | 4.35 | 2.46 | 0.30 | 29.1 | 11.8 | 1.14 | .262 | 2.64 | 63 | 2.08 | 58 | 5.87 | 45.4 |
| 10 | | B. Feller | 1 | 348 | 48 | 26 | 15 | .634 | 42 | 2.18 | 36 | 10 | 4 | 371.1 | 277 | 90 | 101 | 11 | 153 | 3 | 5 | 1,512 | 3 | 8.43 | 3.71 | 2.27 | 0.27 | 23.0 | 10.1 | 1.16 | .267 | 2.45 | 65 | 2.16 | 65 | 6.71 | 48.3 |
Dodgers
Padres
Giants
Diamondbacks
Rockies
Phillies
Mets
Brewers
Cubs
Blue Jays
Yankees
Guardians
Tigers
Mariners
Astros
CIN
STL
ATL
WSH
ATH
BOS
TBR
