Ty Cobb has the fewest career strikeouts when making 13,000+ plate appearances, with 681 strikeouts.
| NAME | SO | PA | G | AB | R | H | 2B | 3B | HR | RBI | BB | HBP | SB | CS | TB | XBH | SH | SF | IBB | GIDP | AVG | OBP | SLG | OPS | WRC | WRAA | WOBA | WRC+ | BRAA | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | T. Cobb | 681 | 13,068 | 3,034 | 11,434 | 2,244 | 4,189 | 724 | 295 | 117 | 1,933 | 1,249 | 94 | 897 | 5,854 | 1,136 | 291 | .366 | .433 | .512 | .945 | 2534 | 1,093.6 | .445 | 165 | 975.1 | ||||
| 2 |  | P. Rose | 1,143 | 15,861 | 3,562 | 14,053 | 2,165 | 4,256 | 746 | 135 | 160 | 1,314 | 1,566 | 107 | 198 | 149 | 5,752 | 1,041 | 56 | 79 | 167 | 247 | .303 | .375 | .409 | .784 | 2190 | 480.1 | .354 | 121 | 368.7 |
| 3 |  | H. Aaron | 1,383 | 13,940 | 3,298 | 12,364 | 2,174 | 3,771 | 624 | 98 | 755 | 2,297 | 1,402 | 32 | 240 | 73 | 6,856 | 1,477 | 21 | 121 | 293 | 328 | .305 | .374 | .555 | .928 | 2453 | 936.4 | .403 | 153 | 858.5 |
| 4 |  | C. Yastrzemski | 1,393 | 13,991 | 3,308 | 11,988 | 1,816 | 3,419 | 646 | 59 | 452 | 1,844 | 1,845 | 40 | 168 | 116 | 5,539 | 1,157 | 13 | 105 | 190 | 323 | .285 | .379 | .462 | .841 | 2155 | 643.2 | .375 | 130 | 469.8 |
| 5 |  | A. Pujols | 1,404 | 13,041 | 3,080 | 11,421 | 1,914 | 3,384 | 686 | 16 | 703 | 2,218 | 1,373 | 123 | 117 | 43 | 6,211 | 1,405 | 1 | 123 | 316 | 426 | .296 | .374 | .544 | .918 | 2233 | 685 | .385 | 141 | 673 |
| 6 |  | R. Henderson | 1,694 | 13,346 | 3,081 | 10,961 | 2,295 | 3,055 | 510 | 66 | 297 | 1,115 | 2,190 | 98 | 1,406 | 335 | 4,588 | 873 | 30 | 67 | 61 | 172 | .279 | .401 | .419 | .820 | 2074 | 509.6 | .372 | 132 | 507.9 |
StatMuse has season-level data for strikeouts going back to the 1891 season.
Tigers 
Guardians 
Royals 
Twins 
White Sox 
Phillies 
Mets 
Brewers 
Cubs 
Dodgers 
Padres 
Blue Jays 
Red Sox 
Astros 
Mariners 
WSH 
STL 
LAA 
SFG 
BAL 
CIN 
MIA 
NYY 
