Chicago White Sox (65-60, first in the AL Central) vs. Chicago Cubs (74-53, second in the NL Central)

Chicago; Wednesday, 2:20 p.m. EDT

PITCHING PROBABLES: White Sox: TBD; Cubs: Clay Holmes (5-5, 2.56 ERA, 1.07 WHIP, 49 strikeouts)

LINE: Cubs -175, White Sox +152; over/under is 9 1/2 runs

BOTTOM LINE: The Chicago Cubs meet the Chicago White Sox looking to sweep their three-game series.

Chicago has a 74-53 record overall and a 38-26 record in home games. Cubs hitters have a collective .419 slugging percentage to rank third in the NL.

Chicago is 65-60 overall and 28-36 in road games. The White Sox have gone 45-24 in games when they record eight or more hits.

The matchup Wednesday is the sixth time these teams meet this season. The Cubs hold a 3-2 advantage in the season series.

TOP PERFORMERS: Alex Bregman has 24 doubles, a triple, 16 home runs and 63 RBIs while hitting .257 for the Cubs. Nico Hoerner is 13 for 40 with two doubles over the last 10 games.

Miguel Vargas has 28 doubles, a triple and 28 home runs for the White Sox. Chase Meidroth is 13 for 42 with four doubles, three home runs and nine RBIs over the past 10 games.

LAST 10 GAMES: Cubs: 6-4, .259 batting average, 5.36 ERA, outscored opponents by one run

White Sox: 6-4, .259 batting average, 3.89 ERA, outscored opponents by 12 runs

INJURIES: Cubs: Kevin Gausman: day-to-day (hand), Dansby Swanson: 10-Day IL (side), Edward Cabrera: 15-Day IL (blister), Daniel Palencia: 60-Day IL (elbow), Hoby Milner: 15-Day IL (appendicitis), Gavin Hollowell: 15-Day IL (shoulder), Matt Shaw: 10-Day IL (hand), Riley Martin: 60-Day IL (elbow), Christopher Austin: 60-Day IL (knee), Phil Maton: 15-Day IL (knee), Ben Brown: 60-Day IL (neck), Justin Steele: 60-Day IL (elbow), Hunter Harvey: 60-Day IL (tricep), Porter Hodge: 60-Day IL (elbow), Cade Horton: 60-Day IL (forearm), Shelby Miller: 60-Day IL (elbow)

White Sox: Drew Thorpe: 60-Day IL (elbow), Jordan Leasure: 60-Day IL (flexor), Davis Martin: 15-Day IL (finger), Prelander Berroa: 60-Day IL (elbow), Ky Bush: 60-Day IL (elbow), Chris Murphy: 15-Day IL (flexor), Joey Bart: 10-Day IL (hand), Kyle Teel: 10-Day IL (ankle), Tanner Murray: 60-Day IL (shoulder), Brooks Baldwin: 60-Day IL (elbow), Mike Vasil: 60-Day IL (elbow)

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The Associated Press created this story using technology provided by Data Skrive and data from Sportradar.