Connexa Sports Technologies (YYAI) had the highest return between 2020 and 2021 by a US stock, returning 13,759,900%.

ASSET	YEARS	% RETURN
Connexa Sports Technologies (YYAI)	2020-2021	13,759,900%
BioNexus Gene Lab Corp Common stock (BGLC)	2020-2021	6,234,046.34%
MDxHealth SA ADR (MDXH)	2020-2021	865,354.55%
Integra Resources (ITRG)	2020-2021	358,233.33%
INVO Fertility (IVF)	2020-2021	277,400.01%
Guardforce AI (GFAI)	2020-2021	207,592.31%
Bone Biologics (BBLG)	2020-2021	126,620%
Applied Digital (APLD)	2020-2021	58,094.44%
Diversified Energy (DEC)	2020-2021	44,900%
CIMG (IMG)	2020-2021	23,105.53%
DeFi Technologies (DEFT)	2020-2021	9,963.03%
COSCIENS Biopharma (CSCI)	2020-2021	8,035.59%
Firefly Neuroscience (AIFF)	2020-2021	3,707.69%
HIVE Blockchain Technologies (HIVE)	2020-2021	3,541.38%
Novavax (NVAX)	2020-2021	3,485.71%
American Battery Technology Company Common Stock (ABAT)	2020-2021	3,243.75%
374Water Inc Common Stock (SCWO)	2020-2021	3,066.67%
Graf Industrial Corp Warrants (each warrant exercisable for one-half of one share of common stock each at an exercise price of $1150 per share) (GRAF.WT)	2020-2021	2,944.83%
Ascent Solar Technologies, Inc Common Stock (ASTI)	2020-2021	2,400%
GameStop (GME)	2020-2021	2,316.78%
Vivid Seats (SEAT)	2020-2021	2,113.02%
Galaxy Digital (GLXY)	2020-2021	2,095.09%
Iqstel (IQST)	2020-2021	2,062.85%
Lightwave Logic (LWLG)	2020-2021	2,025.71%
CPI Card (PMTS)	2020-2021	1,961.11%