Celestica (CLS) had the highest return between 2021 and 2024 by a large-cap US stock, returning 1,032.5%.

ASSET	YEARS	% RETURN
Celestica (CLS)	2021-2024	1,032.52%
Permian Resources (PR)	2021-2024	941.38%
NVIDIA (NVDA)	2021-2024	927.38%
Super Micro Computer (SMCI)	2021-2024	858.49%
Modine Manufacturing (MOD)	2021-2024	818.62%
Sterling Infrastructure (STRL)	2021-2024	801.77%
Enlight Renewable Energy Ltd Ordinary Shares (ENLT)	2021-2024	780.61%
YPF Sociedad Anonima (YPF)	2021-2024	780.12%
FTAI Aviation (FTAI)	2021-2024	749.88%
Comfort Systems USA (FIX)	2021-2024	720.24%
Vistra (VST)	2021-2024	676.26%
Targa Resources (TRGP)	2021-2024	620.16%
MicroStrategy (MSTR)	2021-2024	595.65%
Antero Resources (AR)	2021-2024	529.26%
Globalstar, Inc Common Stock (GSAT)	2021-2024	527.27%
Carpenter Technology (CRS)	2021-2024	518.17%
Arista Networks (ANET)	2021-2024	508.23%
Vertiv (VRT)	2021-2024	507.35%
Constellation Energy (CEG)	2021-2024	505.45%
Broadcom (AVGO)	2021-2024	481.3%
Credo Technology (CRDO)	2021-2024	455.45%
Viper Energy Ut (VNOM)	2021-2024	440.28%
Embraer (EMBJ)	2021-2024	431.59%
EMCOR (EME)	2021-2024	400.39%
Texas Pacific Land (TPL)	2021-2024	393.83%

Large-cap stocks are treated as having a market cap of $10B+.