Cisco Systems (CSCO) had the highest return between 1993 and 1997 by a mega-cap US stock, returning 749.5%.

ASSET	YEARS	% RETURN
Cisco Systems (CSCO)	1993-1997	749.54%
Applied Materials (AMAT)	1993-1997	608.91%
Micron Technology (MU)	1993-1997	591.4%
Intel (INTC)	1993-1997	554.37%
Microsoft (MSFT)	1993-1997	508.22%
ASML Holding NV New York Registry Shares (ASML)	1993-1997	500.01%
Eli Lilly and (LLY)	1993-1997	437.05%
Oracle (ORCL)	1993-1997	433.16%
American Express (AXP)	1993-1997	357.99%
International Business Machines (IBM)	1993-1997	337.72%
Wells Fargo (WFC)	1993-1997	311.95%
Texas Instruments (TXN)	1993-1997	307.47%
Morgan Stanley (MS)	1993-1997	301.1%
Berkshire Hathaway (BRK.A)	1993-1997	292.32%
Caterpillar (CAT)	1993-1997	289.85%
GE Aerospace (GE)	1993-1997	287.85%
JPMorgan Chase (JPM)	1993-1997	246.72%
RTX (RTX)	1993-1997	244.17%
Coca-Cola (KO)	1993-1997	240.57%
Procter & Gamble (PG)	1993-1997	227.99%
Thermo Fisher Scientific (TMO)	1993-1997	215.13%
Shell PLC ADR (SHEL)	1993-1997	196.56%
Johnson & Johnson (JNJ)	1993-1997	188.73%
LIN TV (LIN)	1993-1997	187.36%
Bank of America (BAC)	1993-1997	185.73%

Mega-cap stocks are treated as having a market cap of $200B+.