ASML Holding NV New York Registry Shares (ASML) had the highest return between 1995 and 1997 by a mega-cap US stock, returning 500%.

ASSET	YEARS	% RETURN
ASML Holding NV New York Registry Shares (ASML)	1995-1997	500.01%
Cisco Systems (CSCO)	1995-1997	377.89%
Eli Lilly and (LLY)	1995-1997	355.23%
Intel (INTC)	1995-1997	344.51%
Microsoft (MSFT)	1995-1997	320.32%
Gilead Sciences (GILD)	1995-1997	302.47%
Wells Fargo (WFC)	1995-1997	266.37%
Morgan Stanley (MS)	1995-1997	265.51%
Costco Wholesale (COST)	1995-1997	246.61%
JPMorgan Chase (JPM)	1995-1997	246.53%
American Express (AXP)	1995-1997	220.64%
GE Aerospace (GE)	1995-1997	208.95%
Bank of America (BAC)	1995-1997	204.75%
Merck (MRK)	1995-1997	197.88%
International Business Machines (IBM)	1995-1997	193.61%
Applied Materials (AMAT)	1995-1997	188.63%
Procter & Gamble (PG)	1995-1997	172.64%
Coca-Cola (KO)	1995-1997	167.79%
Johnson & Johnson (JNJ)	1995-1997	152.95%
Royal Bank of Canada (RY)	1995-1997	147.91%
RTX (RTX)	1995-1997	147.9%
Texas Instruments (TXN)	1995-1997	147.32%
LIN TV (LIN)	1995-1997	127.74%
ExxonMobil (XOM)	1995-1997	125.47%
Berkshire Hathaway (BRK.A)	1995-1997	124.39%

Mega-cap stocks are treated as having a market cap of $200B+.