Palantir Technologies (PLTR) had the highest return between 2023 and 2025 by a mega-cap US stock, returning 2,601.4%.

ASSET	YEARS	% RETURN
Palantir Technologies (PLTR)	2023-2025	2,601.37%
NVIDIA (NVDA)	2023-2025	1,157.06%
Sandisk (SNDK)	2023-2025	577.07%
Broadcom (AVGO)	2023-2025	540.69%
GE Aerospace (GE)	2023-2025	497.29%
Micron Technology (MU)	2023-2025	472.71%
GE Vernova LLC (GEV)	2023-2025	469.67%
Facebook (META)	2023-2025	441.2%
Banco Santander SA ADR (SAN)	2023-2025	336.77%
Arista Networks (ANET)	2023-2025	326.43%
Taiwan Semiconductor Manufacturing (TSM)	2023-2025	318.07%
Lam Research (LRCX)	2023-2025	311.04%
Tesla (TSLA)	2023-2025	279.61%
Alphabet Inc Class A (GOOGL)	2023-2025	252.01%
Dell Technologies (DELL)	2023-2025	230.41%
KLA (KLAC)	2023-2025	225.88%
Advanced Micro Devices (AMD)	2023-2025	224.48%
Netflix (NFLX)	2023-2025	214.57%
HSBC Holdings PLC ADR (HSBC)	2023-2025	202.38%
Eli Lilly and (LLY)	2023-2025	200.47%
Citigroup (C)	2023-2025	184.45%
Goldman Sachs (GS)	2023-2025	174.32%
Amazon (AMZN)	2023-2025	170.09%
Applied Materials (AMAT)	2023-2025	164.62%
Palo Alto Networks (PANW)	2023-2025	160.68%

Mega-cap stocks are treated as having a market cap of $200B+.