Praxis Precision Medicines (PRAX) had the highest return between October 1, 2025 and December 31, 2025 by a mid-cap US stock, returning 458.9%.
| ASSET | DATE | % RETURN |
|---|---|---|
Praxis Precision Medicines (PRAX) | 10/1/2025 - 12/31/2025 | 458.85% |
Terns Pharmaceuticals (TERN) | 10/1/2025 - 12/31/2025 | 437.23% |
Capricor Therapeutics (CAPR) | 10/1/2025 - 12/31/2025 | 300.28% |
Hycroft Mining (HYMC) | 10/1/2025 - 12/31/2025 | 277.9% |
AXT (AXTI) | 10/1/2025 - 12/31/2025 | 264.14% |
PACS (PACS) | 10/1/2025 - 12/31/2025 | 183.32% |
Cogent Biosciences (COGT) | 10/1/2025 - 12/31/2025 | 151.91% |
Structure Therapeutics Inc American Depositary Shares (GPCR) | 10/1/2025 - 12/31/2025 | 148.57% |
Alumis (ALMS) | 10/1/2025 - 12/31/2025 | 146.46% |
Vicor (VICR) | 10/1/2025 - 12/31/2025 | 123.13% |
Babcock & Wilcox Enterprises (BW) | 10/1/2025 - 12/31/2025 | 120.14% |
Central Puerto (CEPU) | 10/1/2025 - 12/31/2025 | 116.58% |
Belite Bio Inc ADR (BLTE) | 10/1/2025 - 12/31/2025 | 116.58% |
BBVA Banco Frances SA ADR (BBAR) | 10/1/2025 - 12/31/2025 | 111.94% |
Banco Macro SA B ADR (BMA) | 10/1/2025 - 12/31/2025 | 110.33% |
Celcuity LLC (CELC) | 10/1/2025 - 12/31/2025 | 103.22% |
Sigma Lithium Resources (SGML) | 10/1/2025 - 12/31/2025 | 101.99% |
Victoria's Secret (VSCO) | 10/1/2025 - 12/31/2025 | 97.63% |
Grupo Financiero Galicia SA ADR (GGAL) | 10/1/2025 - 12/31/2025 | 96.76% |
Spyre Therapeutics (SYRE) | 10/1/2025 - 12/31/2025 | 95.82% |
Arrowhead Pharmaceuticals (ARWR) | 10/1/2025 - 12/31/2025 | 92.21% |
Apogee Therapeutics, Inc Common Stock (APGE) | 10/1/2025 - 12/31/2025 | 90.8% |
Immunome (IMNM) | 10/1/2025 - 12/31/2025 | 87.11% |
Fluence Energy (FLNC) | 10/1/2025 - 12/31/2025 | 79.82% |
Amicus Therapeutics (FOLD) | 10/1/2025 - 12/31/2025 | 78.67% |
Mid-cap stocks are treated as having a market cap between $2B and $10B.
