QMMM Holdings Limited Ordinary Shares (QMMM) has had the highest return between 2023 and 2025 by a mid-cap US stock, returning 3,880%.

ASSET	YEARS	% RETURN
QMMM Holdings Limited Ordinary Shares (QMMM)	2023-2025	3,880%
Cipher Mining (CIFR)	2023-2025	3,453.63%
Soleno Therapeutics (SLNO)	2023-2025	3,130.14%
Diginex Limited Ordinary Shares (DGNX)	2023-2025	2,859.62%
Dave (DAVE)	2023-2025	2,659.16%
Innodata (INOD)	2023-2025	2,475.97%
Regencell Bioscience (RGC)	2023-2025	2,140.77%
Terawulf (WULF)	2023-2025	1,935.82%
Sezzle (SEZL)	2023-2025	1,920.66%
Applied Opt (AAOI)	2023-2025	1,818.56%
Applied Digital (APLD)	2023-2025	1,717.46%
American Superconductor (AMSC)	2023-2025	1,450.94%
GeneDx (WGS)	2023-2025	1,366.44%
Nano Nuclear Energy Inc Common Stock (NNE)	2023-2025	1,109.44%
IES (IESC)	2023-2025	1,069.12%
Hut 8 Corp Common Stock (HUT)	2023-2025	1,067.64%
Eos Energy Enterprises (EOSE)	2023-2025	998.57%
Powell Industries (POWL)	2023-2025	992.4%
Centrus Energy (LEU)	2023-2025	990.09%
SoundHound AI (SOUN)	2023-2025	947.43%
Bitfarms (BITF)	2023-2025	941.28%
Quantum Computing (QUBT)	2023-2025	901.27%
BigBearai (BBAI)	2023-2025	891.62%
CleanSpark (CLSK)	2023-2025	861.9%
Tutor Perini (TPC)	2023-2025	801.84%

Mid-cap stocks are treated as having a market cap between $2B and $10B.