best performing biotech companies from 1980 to 2025

Mesoblast (MESO) had the highest return between 1980 and 2025 by a US stock in the Biotechnology Industry, returning 18,039,900%.

ASSETYEARS% RETURN
Mesoblast (MESO)
1980-2025
18,039,900%
Forte Biosciences (FBRX)
1980-2025
2,097,592.31%
Avita Medical (RCEL)
1980-2025
862,400%
MDxHealth SA ADR (MDXH)
1980-2025
396,566.67%
Medicus Pharma Ltd Common Stock (MDCX)
1980-2025
218,471.43%
Immatics (IMTX)
1980-2025
209,900%
Evogene (EVGN)
1980-2025
157,042.86%
Amgen (AMGN)
1980-2025
139,659%
Lexaria Bioscience (LEXX)
1980-2025
138,034.33%
Altimmune (ALT)
1980-2025
124,382.76%
Gilead Sciences (GILD)
1980-2025
32,670.27%
Lixte Biotechnology (LIXT)
1980-2025
26,100%
Vertex Pharmaceuticals (VRTX)
1980-2025
9,836.66%
United Therapeutics (UTHR)
1980-2025
7,118.41%
MiMedx (MDXG)
1980-2025
6,670%
Regencell Bioscience (RGC)
1980-2025
6,549.78%
Alnylam Pharmaceuticals (ALNY)
1980-2025
6,418.85%
Biogen (BIIB)
1980-2025
5,766.33%
Incyte (INCY)
1980-2025
5,167.73%
Azitra (AZTR)
1980-2025
4,632.14%
argenx NV ADR (ARGX)
1980-2025
4,598.04%
Regeneron Pharmaceuticals (REGN)
1980-2025
3,427.96%
Alaunos Therapeutics (TCRT)
1980-2025
2,976.19%
Krystal Biotech (KRYS)
1980-2025
2,248%
Insmed (INSM)
1980-2025
2,009.58%