best performing biotech stocks past 10 years with a 1 billion dollar market cap

Immatics (IMTX) has had the highest return between November 8, 2015 and November 8, 2025 by a US stock in the Biotechnology Industry with a market cap of $1B+, returning 180,900%.

ASSETDATE% RETURN
Immatics (IMTX)
11/8/2015 - 11/8/2025
180,900%
180 Life Sciences (ATNF)
11/8/2015 - 11/8/2025
65,782.35%
argenx NV ADR (ARGX)
11/8/2015 - 11/8/2025
4,674.58%
Regencell Bioscience (RGC)
11/8/2015 - 11/8/2025
4,022.86%
Natera (NTRA)
11/8/2015 - 11/8/2025
2,085.87%
Madrigal Pharmaceuticals (MDGL)
11/8/2015 - 11/8/2025
2,050.59%
Krystal Biotech (KRYS)
11/8/2015 - 11/8/2025
1,785.05%
Vericel Corp Ord (VCEL)
11/8/2015 - 11/8/2025
1,702.78%
Insmed (INSM)
11/8/2015 - 11/8/2025
1,046.92%
Ascendis Pharma A-S (ASND)
11/8/2015 - 11/8/2025
1,012.15%
BeiGene (ONC)
11/8/2015 - 11/8/2025
1,004.49%
Merus (MRUS)
11/8/2015 - 11/8/2025
876.72%
Abivax SA American Depositary Shares (ABVX)
11/8/2015 - 11/8/2025
807.5%
Belite Bio Inc ADR (BLTE)
11/8/2015 - 11/8/2025
805.52%
Arrowhead Pharmaceuticals (ARWR)
11/8/2015 - 11/8/2025
637.41%
Viking Therapeutics (VKTX)
11/8/2015 - 11/8/2025
623.82%
EXACT Sciences (EXAS)
11/8/2015 - 11/8/2025
585.09%
Catalyst Pharmaceuticals (CPRX)
11/8/2015 - 11/8/2025
568.44%
Protagonist Therapeutics (PTGX)
11/8/2015 - 11/8/2025
562.83%
Exelixis (EXEL)
11/8/2015 - 11/8/2025
552.96%
BioNTech SE (BNTX)
11/8/2015 - 11/8/2025
525.09%
Celcuity LLC (CELC)
11/8/2015 - 11/8/2025
503.4%
Veracyte (VCYT)
11/8/2015 - 11/8/2025
497.42%
Cytokinetics (CYTK)
11/8/2015 - 11/8/2025
439.55%
Mirum Pharmaceuticals (MIRM)
11/8/2015 - 11/8/2025
423.92%