Sandisk (SNDK) has had the highest return between 2025 and 2026 by a large-cap US stock, returning 3,431.2%.

ASSET	YEARS	% RETURN
Sandisk (SNDK)	2025-2026	3,431.18%
Micron Technology (MU)	2025-2026	936.8%
Lumentum (LITE)	2025-2026	798.49%
Bloom Energy (BE)	2025-2026	758.73%
Western Digital (WDC)	2025-2026	663.28%
Seagate Technology (STX)	2025-2026	639.39%
Nebius (NBIS)	2025-2026	464.31%
Guardant Health (GH)	2025-2026	441.06%
Moderna (MRNA)	2025-2026	374.17%
Frontline (FRO)	2025-2026	337.06%
Intel (INTC)	2025-2026	329.86%
Revolution Medicines (RVMD)	2025-2026	325.65%
Advanced Micro Devices (AMD)	2025-2026	322.59%
Dell Technologies (DELL)	2025-2026	307.46%
Grupo Cibest (CIB)	2025-2026	304.88%
ASE Industrial Holding Co Ltd ADR (ASX)	2025-2026	304.44%
Sasol (SSL)	2025-2026	285.26%
AngloGold Ashanti (AU)	2025-2026	283.42%
Ciena (CIEN)	2025-2026	276.47%
Millicom International Cellular (TIGO)	2025-2026	275.5%
HF Sinclair (DINO)	2025-2026	269.46%
Valero Energy (VLO)	2025-2026	255.95%
BrightSpring Health Services, Inc Common Stock (BTSG)	2025-2026	249.48%
Jfrog (FROG)	2025-2026	237.31%
Marathon Petroleum (MPC)	2025-2026	236.51%

Large-cap stocks are treated as having a market cap of $10B+.