Energy Transfer (ET) had the highest return in April 2016 by a large-cap US stock, returning 80.7%.

ASSET	MONTH	% RETURN
Energy Transfer (ET)	April 2016	80.67%
Kinross Gold (KGC)	April 2016	74.84%
Madrigal Pharmaceuticals (MDGL)	April 2016	66.67%
Teck Resources Ltd Class B (TECK)	April 2016	65.54%
Hecla Mining (HL)	April 2016	61.42%
Coeur Mining (CDE)	April 2016	49.72%
Pan American Silver (PAAS)	April 2016	48.81%
Targa Resources (TRGP)	April 2016	43.47%
Summit Therapeutics (SMMT)	April 2016	42.57%
Freeport-McMoran Copper & Gold (FCX)	April 2016	41.13%
Alamos Gold (AGI)	April 2016	40.85%
Hudbay Minerals (HBM)	April 2016	40.68%
Vale SA ADR (VALE)	April 2016	39.65%
Nebius (NBIS)	April 2016	37.66%
Petroleo Brasileiro Petrobras SA ADR (PBR)	April 2016	36.7%
Agnico Eagle Mines (AEM)	April 2016	34.54%
Newmont Goldcorp (NEM)	April 2016	34.5%
Globalstar, Inc Common Stock (GSAT)	April 2016	32.65%
Devon Energy (DVN)	April 2016	31.41%
Ovintiv (OVV)	April 2016	30.72%
Wheaton Precious Metals (WPM)	April 2016	29.4%
Suzano Papel e Celulose SA ADR (SUZ)	April 2016	28.73%
Advanced Micro Devices (AMD)	April 2016	27.24%
Gerdau SA ADR (GGB)	April 2016	26.72%
ONEOK (OKE)	April 2016	26.41%

Large-cap stocks are treated as having a market cap of $10B+.