QXO (QXO) had the highest return in August 2007 by a large-cap US stock, returning 550%.

ASSET	MONTH	% RETURN
QXO (QXO)	August 2007	550%
Regeneron Pharmaceuticals (REGN)	August 2007	31.4%
Booking (BKNG)	August 2007	30.84%
Suzano Papel e Celulose SA ADR (SUZ)	August 2007	28.43%
Wynn Resorts (WYNN)	August 2007	28.18%
MercadoLibre (MELI)	August 2007	27.82%
Coherent (COHR)	August 2007	26.21%
Insulet (PODD)	August 2007	26.04%
GameStop (GME)	August 2007	24.63%
Tyler Technologies (TYL)	August 2007	23.48%
Vertex Pharmaceuticals (VRTX)	August 2007	20.99%
Biomarin Pharmaceutical (BMRN)	August 2007	19.2%
Ionis Pharmaceuticals (IONS)	August 2007	18.88%
Jefferies Financial (JEF)	August 2007	18.28%
Monolithic Power Systems (MPWR)	August 2007	17.36%
Encompass Health (EHC)	August 2007	17.13%
Nokia (NOK)	August 2007	16.35%
Exelixis (EXEL)	August 2007	15.86%
CACI International (CACI)	August 2007	15.56%
Dick’s Sporting Goods (DKS)	August 2007	15.34%
DexCom (DXCM)	August 2007	15%
Las Vegas Sands (LVS)	August 2007	14.88%
Royal Gold (RGLD)	August 2007	14.19%
Heico (HEI)	August 2007	14.15%
Caseys General Stores (CASY)	August 2007	14.12%

Large-cap stocks are treated as having a market cap of $10B+.