Celsius (CELH) had the highest return between 2016 and 2023 by a large-cap US stock, returning 8,330.5%.

ASSET	YEARS	% RETURN
Celsius (CELH)	2016-2023	8,330.49%
NVIDIA (NVDA)	2016-2023	6,184.58%
Advanced Micro Devices (AMD)	2016-2023	5,221.66%
Shopify Inc Class A Subordinate Voting Shares (SHOP)	2016-2023	2,964.52%
Leonardo DRS, Inc Common Stock (DRS)	2016-2023	2,536.95%
Trade Desk (TTD)	2016-2023	2,402.96%
argenx NV ADR (ARGX)	2016-2023	2,025.31%
Kinsale Capital (KNSL)	2016-2023	1,813.37%
Tesla (TSLA)	2016-2023	1,515.47%
Builders FirstSource (BLDR)	2016-2023	1,441.46%
Axon Enterprise (AXON)	2016-2023	1,419.59%
Deckers Outdoor (DECK)	2016-2023	1,351.53%
MercadoLibre (MELI)	2016-2023	1,307.87%
Texas Pacific Land Trust (TPL)	2016-2023	1,275.61%
Cadence Design Systems (CDNS)	2016-2023	1,261.85%
Ares Management (ARES)	2016-2023	1,248.06%
Petróleo Brasileiro SA - Petrobras (PBR.A)	2016-2023	1,198.02%
Teck Resources Ltd Class B (TECK)	2016-2023	1,179.89%
Fair Isaac (FICO)	2016-2023	1,148.27%
MongoDB (MDB)	2016-2023	1,138.94%
Arista Networks (ANET)	2016-2023	1,110.08%
Super Micro Computer (SMCI)	2016-2023	1,090.37%
Synopsys (SNPS)	2016-2023	1,041.45%
Lam Research (LRCX)	2016-2023	1,037.78%
Quanta Services (PWR)	2016-2023	998.96%

Large-cap stocks are treated as having a market cap of $10B+.