Jack Henry & Associates (JKHY) had the highest return between 1990 and 1993 by a large-cap US stock, returning 3,340.5%.

ASSET	YEARS	% RETURN
Jack Henry & Associates (JKHY)	1990-1993	3,340.47%
Suncor Energy (SU)	1990-1993	2,866.36%
Johnson Controls International (JCI)	1990-1993	2,450%
Cisco Systems (CSCO)	1990-1993	2,335.22%
Aegon NV ADR (AEG)	1990-1993	1,326.5%
Electronic Arts (EA)	1990-1993	1,271.49%
UnitedHealth (UNH)	1990-1993	1,143.25%
Best Buy (BBY)	1990-1993	1,015.88%
PTC (PTC)	1990-1993	1,007.15%
Lam Research (LRCX)	1990-1993	807.19%
Bio-Techne (TECH)	1990-1993	665.15%
Magna International (MGA)	1990-1993	619.04%
Southwest Airlines (LUV)	1990-1993	610.33%
Constellation Brands Inc Class A (STZ)	1990-1993	608.75%
Waste Management (WM)	1990-1993	574.06%
Amgen (AMGN)	1990-1993	476.67%
Toll Brothers (TOL)	1990-1993	447.95%
Charles Schwab (SCHW)	1990-1993	438.45%
Teva Pharma Industries Ltd ADR (TEVA)	1990-1993	432.06%
Applied Materials (AMAT)	1990-1993	429.9%
Royal Gold (RGLD)	1990-1993	426.93%
Microchip Technology (MCHP)	1990-1993	424.38%
Home Depot (HD)	1990-1993	388.83%
Micron Technology (MU)	1990-1993	386.9%
IDEXX Laboratories (IDXX)	1990-1993	337.36%

Large-cap stocks are treated as having a market cap of $10B+.