AngloGold Ashanti (AU) had the highest return between 1996 and 2002 by a large-cap US stock, returning 8,569,066.7%.

ASSET	YEARS	% RETURN
AngloGold Ashanti (AU)	1996-2002	8,569,066.67%
Booking (BKNG)	1996-2002	3,148,366.67%
NVR (NVR)	1996-2002	3,227.39%
Cognizant Technology Solutions Corp Class A (CTSH)	1996-2002	1,344.61%
Johnson Controls International (JCI)	1996-2002	1,161.51%
Jabil Circuit (JBL)	1996-2002	1,133.22%
Expeditors International of Washington (EXPD)	1996-2002	1,001.27%
Biogen (BIIB)	1996-2002	968.55%
Ross Stores (ROST)	1996-2002	949.22%
ResMed (RMD)	1996-2002	840.61%
Best Buy (BBY)	1996-2002	791.7%
Brown & Brown (BRO)	1996-2002	780.62%
TJX Companies (TJX)	1996-2002	778.22%
Amazon (AMZN)	1996-2002	674.82%
eBay (EBAY)	1996-2002	660.56%
Quest Diagnostics (DGX)	1996-2002	658.67%
SEI Investments (SEIC)	1996-2002	642.47%
Qualcomm (QCOM)	1996-2002	612.22%
Nokia (NOK)	1996-2002	581.39%
Cooper Companies (COO)	1996-2002	573.23%
Canadian National Railway (CNI)	1996-2002	539.47%
Ryanair Holdings PLC ADR (RYAAY)	1996-2002	514.26%
CACI International (CACI)	1996-2002	509.88%
Williams-Sonoma (WSM)	1996-2002	491.02%
Bio-Techne (TECH)	1996-2002	471.37%

Large-cap stocks are treated as having a market cap of $10B+.