Expedia (EXPE) had the highest return between 2004 and 2007 by a large-cap US stock, returning 7,722.8%.

ASSET	YEARS	% RETURN
Expedia (EXPE)	2004-2007	7,722.81%
Monster Beverage (MNST)	2004-2007	4,108.44%
Intuitive Surgical (ISRG)	2004-2007	1,788.89%
Apple (AAPL)	2004-2007	1,738.64%
Banco Bradesco SA ADR (BBD)	2004-2007	1,084.14%
First Solar (FSLR)	2004-2007	990.37%
Vale SA ADR (VALE)	2004-2007	941.18%
ArcelorMittal SA ADR (MT)	2004-2007	911.55%
Suzano Papel e Celulose SA ADR (SUZ)	2004-2007	896.21%
CME (CME)	2004-2007	871.36%
Petroleo Brasileiro Petrobras SA ADR (PBR)	2004-2007	859.34%
Illumina (ILMN)	2004-2007	711.78%
HF Sinclair (DINO)	2004-2007	665.21%
Elbit Systems (ESLT)	2004-2007	664.36%
Grupo Cibest (CIB)	2004-2007	656.75%
Ambev SA ADR (ABEV)	2004-2007	648.98%
Tenaris SA ADR (TS)	2004-2007	643.43%
Deckers Outdoor (DECK)	2004-2007	628%
America Movil SAB de CV ADR (AMX)	2004-2007	622.18%
Alphabet Inc Class A (GOOGL)	2004-2007	591.48%
Trip Group Ltd ADR (TCOM)	2004-2007	588.11%
CF Industries (CF)	2004-2007	582.53%
Allegheny Technologies (ATI)	2004-2007	579.6%
Credicorp (BAP)	2004-2007	561.84%
Booking (BKNG)	2004-2007	536.32%

Large-cap stocks are treated as having a market cap of $10B+.