best performing large cap stocks 2016 to 2022

Madrigal Pharmaceuticals (MDGL) had the highest return between 2016 and 2022 by a large-cap US stock, returning 2,413%.

ASSETYEARS% RETURN
Madrigal Pharmaceuticals (MDGL)
2016-2022
2,412.99%
Advanced Micro Devices (AMD)
2016-2022
2,238.27%
argenx NV ADR (ARGX)
2016-2022
2,016.37%
Texas Pacific Land (TPL)
2016-2022
1,934.86%
NVIDIA (NVDA)
2016-2022
1,753.51%
Leonardo DRS, Inc Common Stock (DRS)
2016-2022
1,581.58%
Teck Resources Ltd Class B (TECK)
2016-2022
1,022.23%
Lattice Semiconductor (LSCC)
2016-2022
913.75%
Axon Enterprise (AXON)
2016-2022
876.06%
BioNTech SE (BNTX)
2016-2022
822.48%
Ubiquiti Networks (UI)
2016-2022
788.63%
Deckers Outdoor (DECK)
2016-2022
766.8%
Paycom Software (PAYC)
2016-2022
736.19%
Nova (NVMI)
2016-2022
730.08%
Moderna (MRNA)
2016-2022
716.45%
Vale SA ADR (VALE)
2016-2022
708.61%
Axsome Therapeutics (AXSM)
2016-2022
708.49%
Cadence Design Systems (CDNS)
2016-2022
703.2%
Tesla (TSLA)
2016-2022
700.84%
Fortinet (FTNT)
2016-2022
700.43%
Insulet (PODD)
2016-2022
691.37%
Sitime (SITM)
2016-2022
681.69%
Freedom (FRHC)
2016-2022
675.23%
BeiGene (ONC)
2016-2022
659.2%
MercadoLibre (MELI)
2016-2022
658.11%
Large-cap stocks are treated as having a market cap of $10B+.

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