Tempus AI, Inc Class A Common Stock (TEM) had the highest return in January 2025 by a large-cap US stock, returning 69.3%.

ASSET	MONTH	% RETURN
Tempus AI, Inc Class A Common Stock (TEM)	January 2025	69.34%
Guardant Health (GH)	January 2025	50.34%
BrightSpring Health Services, Inc Common Stock (BTSG)	January 2025	37.21%
Nextpower (NXT)	January 2025	34.85%
Robinhood Markets (HOOD)	January 2025	34.8%
Harmony Gold Mining (HMY)	January 2025	33.85%
Twilio (TWLO)	January 2025	33.8%
Immunitybio (IBRX)	January 2025	33.72%
Celestica (CLS)	January 2025	33.01%
Constellation Energy (CEG)	January 2025	32.51%
Corcept Therapeutics (CORT)	January 2025	32.2%
Nu (NU)	January 2025	27.68%
Arm Holdings plc American Depositary Shares (ARM)	January 2025	27.65%
AngloGold Ashanti (AU)	January 2025	27.36%
CVS Health (CVS)	January 2025	26.8%
Atlassian (TEAM)	January 2025	25.46%
Grupo Cibest (CIB)	January 2025	24.92%
Guidewire Software (GWRE)	January 2025	24.31%
Royalty Pharma (RPRX)	January 2025	23.6%
Carvana (CVNA)	January 2025	23.31%
BeiGene (ONC)	January 2025	23.28%
BridgeBio Pharma (BBIO)	January 2025	23.1%
Futu (FUTU)	January 2025	22.84%
Gold Fields Ltd ADR (GFI)	January 2025	22.77%
Interactive Brokers (IBKR)	January 2025	22.45%

Large-cap stocks are treated as having a market cap of $10B+.