Jack Henry & Associates (JKHY) had the highest return between 1990 and 1992 by a US stock with a market cap of $10B+, returning 2,690.3%.

ASSET	YEARS	% RETURN
Jack Henry & Associates (JKHY)	1990-1992	2,690.29%
Cisco Systems (CSCO)	1990-1992	1,381.34%
Aegon NV ADR (AEG)	1990-1992	950.32%
UnitedHealth (UNH)	1990-1992	831.1%
Electronic Arts (EA)	1990-1992	804.26%
Johnson Controls International (JCI)	1990-1992	800%
Waste Management (WM)	1990-1992	759.22%
Amgen (AMGN)	1990-1992	722.86%
PTC (PTC)	1990-1992	657.14%
Home Depot (HD)	1990-1992	524.82%
Best Buy (BBY)	1990-1992	523.83%
Toll Brothers (TOL)	1990-1992	345.8%
Microsoft (MSFT)	1990-1992	332.85%
Lattice Semiconductor (LSCC)	1990-1992	292.16%
Lam Research (LRCX)	1990-1992	288.75%
Teva Pharma Industries Ltd ADR (TEVA)	1990-1992	284.44%
Constellation Brands Inc Class A (STZ)	1990-1992	282.52%
Magna International (MGA)	1990-1992	280.7%
Jacobs Solutions (J)	1990-1992	280.6%
Southwest Airlines (LUV)	1990-1992	273.24%
Raymond James Financial (RJF)	1990-1992	238.58%
Nike (NKE)	1990-1992	216.54%
Stryker (SYK)	1990-1992	216.32%
Lennar (LEN)	1990-1992	213.5%
Medtronic (MDT)	1990-1992	196.98%