NVIDIA (NVDA) had the highest return between 2018 and 2024 by a large-cap US stock, returning 2,673.5%.

ASSET	YEARS	% RETURN
NVIDIA (NVDA)	2018-2024	2,673.47%
Trade Desk (TTD)	2018-2024	2,472.34%
Axon Enterprise (AXON)	2018-2024	2,141.03%
MicroStrategy (MSTR)	2018-2024	2,100.09%
Tesla (TSLA)	2018-2024	1,841.54%
Natera (NTRA)	2018-2024	1,643.39%
Deckers Outdoor (DECK)	2018-2024	1,439.93%
Super Micro Computer (SMCI)	2018-2024	1,358.37%
Fair Isaac (FICO)	2018-2024	1,197.78%
Vertiv (VRT)	2018-2024	1,075.27%
Advanced Micro Devices (AMD)	2018-2024	1,059.21%
Ares Management (ARES)	2018-2024	1,059.04%
Broadcom (AVGO)	2018-2024	1,002.03%
Fortinet (FTNT)	2018-2024	979.52%
Carvana (CVNA)	2018-2024	961.38%
Leonardo DRS, Inc Common Stock (DRS)	2018-2024	949.03%
Kinsale Capital (KNSL)	2018-2024	948.6%
Shopify Inc Class A Subordinate Voting Shares (SHOP)	2018-2024	946.66%
Chipotle Mexican Grill (CMG)	2018-2024	936.44%
Eli Lilly and (LLY)	2018-2024	922.09%
Comfort Systems USA (FIX)	2018-2024	911.64%
Dick’s Sporting Goods (DKS)	2018-2024	877.78%
argenx NV ADR (ARGX)	2018-2024	868.81%
Celestica (CLS)	2018-2024	779.05%
Vistra Energy (VST)	2018-2024	777.77%

Large-cap stocks are treated as having a market cap of $10B+.