United Therapeutics (UTHR) had the highest return in Q3 2014 by a large-cap US stock, returning 44.4%.

ASSET	QUARTER	% RETURN
United Therapeutics (UTHR)	Q3 2014	44.37%
Arista Networks (ANET)	Q3 2014	31.9%
XPO Logistics (XPO)	Q3 2014	31.12%
Advanced Drainage Systems (WMS)	Q3 2014	30.53%
Monster Beverage (MNST)	Q3 2014	29.31%
Ulta Beauty (ULTA)	Q3 2014	28.96%
CyberArk Software (CYBR)	Q3 2014	28.04%
Gilead Sciences (GILD)	Q3 2014	27.68%
Regeneron Pharmaceuticals (REGN)	Q3 2014	26.28%
Tenet Healthcare (THC)	Q3 2014	26.01%
Steel Dynamics (STLD)	Q3 2014	25.82%
Burlington Stores (BURL)	Q3 2014	24.84%
Southwest Airlines (LUV)	Q3 2014	24.49%
HCA (HCA)	Q3 2014	24.31%
Alnylam Pharmaceuticals (ALNY)	Q3 2014	23.62%
America Movil SAB de CV ADR (AMX)	Q3 2014	22.72%
Dr Reddy’s Laboratories Ltd ADR (RDY)	Q3 2014	21.71%
Royal Caribbean Cruises (RCL)	Q3 2014	21.58%
ICON (ICLR)	Q3 2014	20.48%
Broadcom (AVGO)	Q3 2014	20.47%
Korea Electric Power Corp ADR (KEP)	Q3 2014	20.13%
Texas Pacific Land Trust (TPL)	Q3 2014	20.03%
Vertex Pharmaceuticals (VRTX)	Q3 2014	19.64%
Edwards Lifesciences (EW)	Q3 2014	18.66%
Amgen (AMGN)	Q3 2014	18.21%

Large-cap stocks are treated as having a market cap of $10B+.